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Magnetic pulse compressor for prepulse discharge in spiker-sustainer excitation technique for XeCl lasers (1994)

Giordano, G. ; Letardi, T. ; Muzzi, F. ; [et al.]

[S.l.] : American Institute of Physics (AIP)

Review of Scientific Instruments 65 (1994), S. 2475-2481

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ISSN: 1089-7623

Source: AIP Digital Archive

Topics: Physics , Electrical Engineering, Measurement and Control Technology

Notes: A high-voltage pulse output modulator using a step-up transformer with two stages of magnetic pulse compression circuits has been developed as a spiker for the purpose of obtaining the breakdown of the gas mixture when using the spiker-sustainer excitation technique for pumping XeCl discharge lasers. When the transformer input is fed by a current pulse with a peak value and a full width of 1.16 kA and 1.6 μs, respectively, formed by a discharge of an initially charged 19-kV, 57-nF capacitance in series in the transformer primary loop, the 2.7-nF output capacitor bank (Cp) of the spiker can be charged up to 67 kV with a (10%–90%) rise time of 59 ns. The modulator has been tested at a repetition rate of up to 600 Hz in burst mode using a resistor in parallel with Cp as the load.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1063/1.1144705

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Ultrasound-guided percutaneous laser ablation of liver tissue in a rabbit model (1993)

Pacella, C. M. ; Rossi, Z. ; Bizzarri, G. ; [et al.]

Springer

European radiology 3 (1993), S. 26-32

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ISSN: 1432-1084

Keywords: Liver, interventional procedures ; Lasers ; Liver, US studies ; Liver neoplasms, therapy ; Hyperthermia

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract The present report evaluates the efficacy and safety of percutaneous interstitial laser tissue ablation of the liver in nine New Zealand rabbits. A Nd: YAG laser was coupled to a quartz fibreoptic guide (600 μm) with a flat tip. The fibre and a thermocouple were placed in the lumen of two Chiba needles (18G) and these were inserted into the liver 10 mm apart under ultrasound guidance. The laser was fired for 5 min at 1, 3 and 5 W power, respectively, in three groups of rabbits. There were no acute complications and all the rabbits except one survived until the established time of sacrifice. The procedure induced a cavity surrounded by a zone (about 10 mm) of coagulative necrosis. After 2 weeks a strong peripheral inflammatory response was evident and after 4 weeks a capsule of connective tissue enclosed the lesions. Our study seems to offer a safe and rapid technique producing a “guaranteed kill radius” for the treatment of small hepatic neoplasms.