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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 27 (1955), S. 1848-1848 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of environmental contamination and toxicology 52 (1994), S. 734-741 
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Der Unfallchirurg 100 (1997), S. 547-551 
    ISSN: 1433-044X
    Keywords: Schlüsselwörter Riesenzelltumor ; Qualitätssicherung ; Adjuvante Therapie ; Key words Giant-cell tumor ; Quality assurance ; Adjuvant therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Giant-cell bone tumors display a locally aggressive growth pattern, frequently recur if no adjuvant treatment is given, and may potentially metastasize. By virtue of their biological behavior and typically juxta-articular localization, giant-cell bone tumors require specific surgical management. Thus, an intralesional tumor excision must be supplemented by adjuvant bone cementing, possibly combined with instillation of phenol or cryotherapy. These combined treatment modalities assure a high-quality procedure, defined as the actual way medical care is delivered, by promoting the quality of the outcome, defined as the effect of a medical procedure on the patient's state of health.
    Notes: Der Riesenzelltumor des Knochens zeigt ein lokal aggressives Wachstum, rezidiviert ohne adjuvante Maßnahmen häufig und kann sich potentiell systemisch absiedeln. Aufgrund dieser biologischen Eigenschaften und der typischerweise gelenknahen Lokalisation bedarf der Riesenzelltumor eines speziellen chirurgischen Managements. Eine intraläsionale Tumorexzision muß dabei durch eine adjuvante Knochenzementplombierung, u. U. kombiniert mit Phenolinstillation oder Kryotherapie, ergänzt werden. Diese Kombinationstherapie sichert eine hohe Prozeßqualität (definiert als Art und Weise der Durchführung einer medizinischen Versorgungsleistung), indem sie die Ergebnisqualität (definiert als Auswirkung einer medizinischen Versorgungsleistung auf den Gesundheitszustand des Patienten) fördert.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Der Orthopäde 28 (1999), S. 243-249 
    ISSN: 1433-0431
    Keywords: Key words Preoperative information • Computer based information system ; Schlüsselwörter Aufklärungsgespräch • Computergestützte Patienteninformation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Verschuldete Defizite der ärztlichen Aufklärung machen einen ärztlichen Eingriff insgesamt rechtswidrig und führen deshalb im Grundsatz zur Haftung für alle Schäden. Zur Verminderung dieser Haftungsgefahren wurde ein computergestütztes Aufklärungskonzept entwickelt, mit dessen Hilfe eine individuell auf den Patienten bezogene Arbeitsunterlage erstellt wird. Anhand dieser Unterlage wird das eigentliche Aufklärungsgespräch geführt. Nach Unterschrift des Patienten steht das Schriftstück dem für die Aufklärung beweispflichtigen Arzt zum Nachweis des Aufklärungsinhalts zur Verfügung. Der langjährige Einsatz des Konzepts hat gezeigt, daß damit das Vergessen wesentlicher Punkte und Verständnisschwierigkeiten beim Patienten weitgehend ausgeschlossen werden können und damit eine hohe Aufklärungsqualität erreicht wird.
    Notes: Summary Culpable deficits of the preoperative information cause a complete illegality of the whole medical intervention and lead to liability for any resulting damage. In cases of controversy it's the physician's due to prove the correct preoperative information. To reduce these liability-risks a computer based information system has been developed. With its help an working sheet is provided which is individually adjusted for the patient. Based upon this record the real preoperative information takes place. After the patient signed the record the physician keeps it at his disposal for proving the contents of the preoperative information. The conception's use over many years shows that overlooking essential aspects and misunderstanding can grossly be excluded for the patient and a high quality of information can be reached.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Archives of orthopaedic and trauma surgery 113 (1994), S. 149-152 
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We examined the impact of standardisation of allogenous bone transplantation according to the HIV protection guidelines on procedure quality using a questionnaire. As far as preparation, storage temperature and safety of the transplant are concerned, we showed an improvement in comparison to previous records. Hepatitis C testing has fallen although it is currently being recommended. According to the risk estimate for donors over 60 years the 3-months HIV test was considered unnecessary and was carried out in only 50% of transplants. In 4.5% of transplants no precautions against HIV transmission were taken.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Archives of orthopaedic and trauma surgery 117 (1997), S. 43-46 
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Because of the typical metaphyseal-epiphyseal growth of giant cell tumors and chondroblastomas, the optimal result of an en bloc resection can usually only be achieved by a loss of joint function. For this reason, intralesional excision has prevailed, though it leads to a high rate of relapses. Adjuvant therapy involving irrigation of the remaining bone cavity with phenol can distinctly decrease the rate of relapse. Little is known about the amount of phenol applied that is absorbed. This study investigated the urinary excretion of phenol following the instillation of 102 ml of a 5% phenol solution. The method consisted of urine collection from 11 patients treated by phenol instillation preoperatively, and at 1, 3, 6, 12 and 24 h postoperatively. The urine specimens were analysed for phenol by mass spectrometry. Preoperatively, the value was 5.1 mg/l on average. The maximum concentration of 62 mg/l was found 1 h after instillation, with an average value of 41.5 mg/l, and after 3 h of 18.9 mg/l. A further rapid decrease in the excretion rate was recorded, with normal values being reached after 12 h. This means a maximum of 9% and an average of 2% of the instilled amount of phenol were excreted in the urine within 24 h postoperatively. By comparing these urinary concentrations to published standards, we conclude that the instillation of a 5% phenol solution into bony lesions is associated with a relatively low risk of systemic toxicity.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Archives of orthopaedic and trauma surgery 118 (1998), S. 75-77 
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A discontinuous or thin cement mantle of a socket is associated with increased polyethylene wear and cement fractures. In a retrospective radiological analysis we examined the quality of the cement mantle in cups without (group I = 100 Charnley-Mueller cups) and with (group II = 100 Contemporary cups, Howmedica) bone cement spacers. Under-filling (0–2 mm) and over-filling (〉 8 mm) of the cement mantle were noted and classified. Statistics show significantly less under-filling of the cement mantle in group II than in group I (P = 0.001), in particular when comparing separate cup regions (thirds; P 〈〈 0.001). Furthermore, there is no significant difference in the frequency of overfilling with cement between groups I and II (P = 0.108). To sum up, utilization of an acetabular component with preformed bone cement spacers considerably improves the quality of the cement mantle without additional cost.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Archives of orthopaedic and trauma surgery 116 (1997), S. 334-337 
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The shear and tensile strength of a hydroxyapatite (HA) coating on a femoral component was studied after physiological loading conditions in 8 German Shepherds. A proximal macrostructure on the stem was used to protect this region from shear stresses. Another four implantations with uncoated components were used as controls. In vitro testing of the HA layer demonstrated excellent tensile strength and stability to surface deformation. The loaded implants were tested at 6, 12, and 24 weeks. At 6 weeks the HA-coated components could easily be removed by axial loading, whereas the HA layer remained undamaged on the metal. However, pull out tests of implants older than 12 weeks showed complete debonding of the HA layer from the non-macrostructured surface due to shear forces in all cases. Debonding of the HA layer was also observed with microradiography. The macrostructured surface prevented dislodging of the component from this area at pull out test by distributing shear forces. Unlike in uncoated implants, considerable amounts of bone remained attached onto the HA macrostructure when the surrounding femur was pulled out. Shear forces cause debonding of the HA layer, while tensile stress affects failure within the bone. Physiological loading partially produces gaps at the interface so direct transmission of tensile forces onto the bone is lost, and the coating-metal interface becomes the weak point in the system.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Archives of orthopaedic and trauma surgery 119 (1999), S. 133-138 
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The shear strength of the cement-metal interface using rods with different surface treatments and a clinical standardized cementing technique was studied. Under “dry” conditions, a low interface shear strength can be obtained with polished and smooth CoCrMo surfaces (peak-to-valley height R t : 1 μm, average 0.2 MPa; 5 μm, 0.38 MPa). Grit-blasted and polymethylmethacrylate (PMMA)-precoated surfaces achieved higher values (PMMA precoat: average 5.16 MPa; CoCrMo peak-to-valley height R t : 20 μm, average 8.61 MPa; 60 μm, average 7.8 MPa). After immersion in physiological saline solution for 60 days, the PMMA-precoated rods kept their initial stability whereas all the other test rods had lost their stability completely. A microscopic analysis of cross-sections revealed gap formations at the cement-metal interface to varying degrees (1–16 μm). PMMA-precoated rods rarely showed any gap formation at all. The above-mentioned gap formation was seen independently of the porosity at the cement-metal interface and corresponds to the clinical and postmortem observed debonding of the interface.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Archives of orthopaedic and trauma surgery 108 (1989), S. 359-362 
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The Girdlestone hip is a possible alternative in cases where reconstruction and reimplantation appear hopeless. Only a minority of the 22 patients we followed for up to 16 years have had results ranging from good to satisfactory.
    Type of Medium: Electronic Resource
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