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  • 1
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    Development of microsatellite markers in the toxic dinoflagellate Alexandrium minutum (Dinophyceae) (2006)
    Details
    Publication Date: 2022-05-25
    Description: Author Posting. © Blackwell, 2006. This is the author's version of the work. It is posted here by permission of Blackwell for personal use, not for redistribution. The definitive version was published in Molecular Ecology Notes 6 (2006): 756-758, doi:10.1111/j.1471-8286.2006.01331.x.
    Description: Outbreaks of paralytic shellfish poisoning caused by the toxic dinoflagellate Alexandrium minutum (Dinophyceae) are a worldwide concern from both the economic and human health points of view. For population genetic studies of A. minutum distribution and dispersal, highly polymorphic genetic markers are of great value. We isolated 12 polymorphic microsatellites from this cosmopolitan, toxic dinoflagellate species. These loci provide one class of highly variable genetic markers, as the number of alleles ranged from 4 to 12, and the estimate of gene diversity was from 0.560 to 0.862 across the 12 microsatellites; these loci have the potential to reveal genetic structure and gene flow among A. minutum populations.
    Description: Support for this research provided in part (to DMA) by U.S. National Science Foundation grants OCE-0136861 and OCE-0430724, and the National Institute of Environmental Health Sciences Grant 1 P50 ES012742-01.
    Keywords: Alexandrium minutum ; Microsatellite ; Paralytic shellfish poisoning ; Phytoplankton ; SSR ; Toxic dinoflagellate
    Repository Name: Woods Hole Open Access Server
    Type: Preprint
    Format: 189512 bytes
    Format: application/pdf
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  • 2
    Electronic Resource
    Electronic Resource
    Structures of 2,2'-polymethylene-1,1'-biisoquinolinium dibromides (1992)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 48 (1992), S. 894-897 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270191011885
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Structure of diiodide salts of N-heteroaromatic dications (1993)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 49 (1993), S. 1398-1401 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270193000393
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    SOS-inducing activity of mono- and sesquiterpene-glucosides
    Amsterdam : Elsevier
    Mutation Research/Environmental Mutagenesis and Related Subjects 272 (1992), S. 273-274 
    Details
    ISSN: 0165-1161
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0165-1161(92)91598-L
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Ge(Li) summing spectrometers of special type
    Amsterdam : Elsevier
    Nuclear Instruments and Methods 128 (1975), S. 53-60 
    Details
    ISSN: 0029-554X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0029-554X(75)90773-9
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Idiopathic spinal cord herniation (1996)
    Springer
    Neuroradiology 38 (1996), S. 155-156 
    Details
    ISSN: 1432-1920
    Keywords: Key words Spinal cord ; herniation ; Dura Mater ; duplication ; Magnetic resonance imaging ; Computed tomographic myelography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Idiopathic spinal cord herniation is a rare disease, few cases having been reported. We encountered a case of idiopathic spinal cord herniation presenting with severe spasticity in the right leg and urinary dysfunction. The spinal cord was herniated into a cavity created by duplication of the dura mater and resection of the inner layer improved the neurological deficits. MRI, myelography, and CT myelography were useful for diagnosing this disease. Four radiological signs of spinal cord herniation are described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00604805
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Idiopathic spinal cord herniation (1996)
    Springer
    Neuroradiology 38 (1996), S. 155-156 
    Details
    ISSN: 1432-1920
    Keywords: Spinal cord, herniation ; Dura Mater, duplication ; Magnetic resonance imaging ; Computed tomographic myelography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Idiopathic spinal cord herniation is a rare disease, few cases having been reported. We encountered a case of idiopathic spinal cord herniation presenting with severe spasticity in the right leg and urinary dysfunction. The spinal cord was herniated into a cavity created by duplication of the dura mater and resection of the inner layer improved the neurological deficits. MRI, myelography, and CT myelography were useful for diagnosing this disease. Four radiological signs of spinal cord herniation are described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00604805
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    A note on stochastic modeling of shunting inhibition (1976)
    Springer
    Biological cybernetics 24 (1976), S. 139-145 
    Details
    ISSN: 1432-0770
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Computer Science , Physics
    Notes: Abstract Stochastic modeling of a neuron with a shunting inhibition is considered. The shunting inhibition divides a neuron potential, and in this case, the neuron has a state-dependent noise. The effect of this state-dependency is discussed by means of a comparison with a subtractive inhibition which was treated in a previous paper. Attention is focused on the firing statistics of both inhibitions described by the first passage time of a neuron potential. These statistics differ depending on the reset value of the potential. This is due to the fact that the shunting inhibition is effective when the potential is close to a threshold. Numerical examples illustrating this effect are given.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00364116
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  • 9
    Electronic Resource
    Electronic Resource
    Second cancers after adjuvant tamoxifen therapy for breast cancer in Japan (2000)
    Springer
    Annals of oncology 11 (2000), S. 1539-1544 
    Details
    ISSN: 1569-8041
    Keywords: adjuvant therapy ; breast cancer ; second cancer ; tamoxifen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background:Women treated with tamoxifen for breast cancer are atincreased risk of endometrial cancer. We conducted a retrospective cohortstudy to evaluate the risk of second primary cancers after adjuvant tamoxifentherapy for breast cancer in Japan. Patients and methods:The subjects of the study were 6148 womenwho had been diagnosed with stage I, II, or IIIA unilateral primary breastcancer and had received surgical treatment during the period from January 1982through December 1990 at nine institutions in Japan. The information on eachpatient was obtained from medical records or a prospectively compiled computerdatabase at each institution. Results:Of the 6148 women, 3588 (58.4%) were administeredtamoxifen as an adjuvant treatment and 2560 (41.6%) were notadministered. Median follow-up periods were 7.64 years for tamoxifen-treatedpatients and 8.10 years for non-tamoxifen-treated patients, respectively. Theduration of tamoxifen treatment was mostly two years or less (80.7%),and few patients received tamoxifen for more than five years. The cumulativeincidence rates of all second cancers at 10 years were 4.61% and4.09% among tamoxifen-treated and non-tamoxifen-treated patients(P = 0.62), respectively, and the incidence rate ratio (IRR) forall second cancers was 1.06 (95% confidence interval (CI):0.77–1.47) after adjustment of several covariates. The numbers ofendometrial cancers was 9 and 3 among tamoxifen-treated andnon-tamoxifen-treated patients, respectively, and the IRR was 2.37 (95%CI: 0.64–8.77, P = 0.20). Of the 12 patients who developedendometrial cancer, 4 died of cancer (for 3 of them, the cause of death wasbreast cancer), and the other 8 patients were alive as of March 1996. Stomachcancer was the most frequent second cancer and the IRR was 1.34 (95%CI: 0.76–2.38, P = 0.31). There was no substantialincrease in any other type of gastrointestinal cancer such as colorectal andliver cancers among tamoxifen-treated patients. Conclusions:The incidence and risk of second primary cancersassociated with tamoxifen therapy is low. The potential benefit of adjuvanttamoxifen therapy in breast cancer patients outweighs the risk of secondprimary cancers for Japanese breast cancer patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008383804811
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  • 10
    Electronic Resource
    Electronic Resource
    Donor-Acceptor-Wechselwirkungen in Polymer-Systemen. 2. Mitt. Polyester aus N-[5,5-Bis(hydroxy-methyl)hexyl]carbazol (1977)
    Springer
    Colloid & polymer science 255 (1977), S. 826-826 
    Details
    ISSN: 1435-1536
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01664578
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