Publication Date:
2018-10-09
Description:
Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control, Published online: 08 October 2018; doi:10.1038/s41467-018-06611-5 Spatial mapping of genomic programs in tissue cells is an important step in the understanding of organ function and disease. Here, the authors provide a spatially resolved epigenomic and transcriptomic map of human liver and show porto-central gradients in metabolic and morphogen networks and transcription factor binding sites as a basis to better understand liver regeneration and function.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics
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