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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Steroid Biochemistry 25 (1986), S. 71 
    ISSN: 0022-4731
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Steroid Biochemistry 25 (1986), S. 71 
    ISSN: 0022-4731
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Location Call Number Limitation Availability
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  • 3
    ISSN: 1432-0584
    Keywords: Calcitriol ; Vitamin D ; Lymphocytes ; Monocytes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The possible role played by monocytes in the inhibitory effect of calcitriol on phytohemagglutinin (PHA)-stimulated lymphocyte proliferation was assessed by testing the effect of this sterol under different cell culture conditions. Calcitriol had a dose-dependent inhibitory effect on lymphocyte proliferation in concentrations ranging from 10−10 up to 10−8 M. The effect of 10−9 M calcitriol was almost completely abolished by: a) monocyte depletion, b) inhibition of prostaglandin (PG) synthesis by indomethacin, and c) addition of exogenous interleukin-2 (IL-2). These results suggested that the inhibitory effect of calcitriol was mediated through monocytes. This possibility was substantiated by the following observations: a) the calcitriol inhibitory effect was restored when autologous adherent cells were added to monocyte-depleted PBM cells; b) the supernatant of adherent cells cultured for 24 hours in the presence of calcitriol exerted a marked inhibitory effect on lymphocyte proliferation; and c) this effect was not longer evident when adherent cells were cultured in the presence of calcitriol plus indomethacin. These data support the hypothesis that calcitriol acts, at least partially, through the monocytes, inducing an increased release of PG, with subsequent inhibition of IL-2 synthesis, then resulting in a decreased lymphocyte proliferation.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Aquaculture 25 (1981), S. 59-65 
    ISSN: 0044-8486
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    International urogynecology journal 11 (2000), S. 45-47 
    ISSN: 1433-3023
    Keywords: Key words:Calculus; Diverticulum; Urethra
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: Urethral diverticula with calculi are rare. This 5 × 6 cm calculus presented in a patient with recurrent urinary tract infections. Local excision was effective.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0819
    Keywords: Key words Mexican Active Volcanoes ; Chichon Volcano ; Phreatomagmatic eruptions ; Wet and dry surge deposits
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract  Additional data from proximal areas enable a reconstruction of the stratigraphy and the eruptive chronology of phases III and IV of the 1982 eruption of El Chichón Volcano. Phase III began on 4 April at 0135 GMT with a powerful hydromagmatic explosion that generated radially fast-moving (∼100 ms–1) pyroclastic clouds that produced a surge deposit (S1). Due to the sudden reduction in the confining pressure the process continued by tapping of magma from a deeper source, causing a new explosion. The ejected juvenile material mixed with large amounts of fragmented dome and wall rock, which were dispersed laterally in several pulses as lithic-rich block-and-ash flow (F1). Partial evacuation of juvenile material from the magmatic system prompted the entrance of external water to generate a series of hydromagmatic explosions that dispersed moisture-rich surge clouds and small-volume block-and-ash flows (IU) up to distances of 3 km from the crater. The eruption continued by further decompression of the magmatic system, with the ensuing emission of smaller amounts of gas-rich magma which, with the strong erosion of the volcanic conduit, formed a lithic-rich Plinian column that deposited fallout layer B. Associated with the widening of the vent, an increase in the effective density of the uprising column took place, causing its collapse. Block-and-ash flows arising from the column collapse traveled along valleys as a dense laminar flow (F2). In some places, flow regime changes due to topographic obstacles promoted transformation into a turbulent surge (S2) which attained minimum velocities of approximately 77 ms–1 near the volcano. The process continued with the formation of a new column on 4 April at 1135 GMT (phase IV) that emplaced fall deposit C and was followed by hydromagmatic explosions which produced pyroclastic surges (S3).
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0819
    Keywords: Stratigraphy ; Evolution ; El Chichón ; México
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: 2 abundance and depletion in MgO, CaO, TiO2, as well as trace and rare earth elements. This suggests segregation of olivine and orthopyroxene from the melt. Since human settlements in southeast Mexico and Central America can be traced as far back as approximately 2500 years BP, most of these events probably affected human activity. In fact, there are reports of pottery shards and other artifacts in deposits from the eruption of 1250 BP. Pottery fragments in deposits of an eruption that took place 2500 BP are also reported in this paper. Thus, the impact of the volcano on human activities has been frequent, with most of the repose intervals lasting between 100 to 600 years. The impact of the eruptions was probably of greater than local extent, because airfall tephra could reach distant sites and possibly even affect weather. The eruptive history of El Chichón also offers clues in the investigation of the Maya civilization. Several researchers have considered the volcano as an important factor in the answer to some intriguing questions such as the extensive use of volcanic ash in Late Classic Maya ceramics or, of greater importance, the causes of the collapse of the Classic Maya civilization.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 24 (1983), S. 109-112 
    ISSN: 1432-1041
    Keywords: cefroxadine ; haemodialysis ; pharmacokinetics ; terminal renal impairment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The pharmacokinetics of cefroxadine was studied in 17 patients with terminal renal impairment, 10 of whom were undergoing 5 h dialysis sessions. The antibiotic was administered as a single oral dose of 500 mg. Cefroxadine followed a single compartment open kinetic model. During the interdialysis period in patients with terminal renal impairment, an average Cmax of 26.59 µg/ml and a tmax of 3.65 h were reached, which are greater than in patients with normal renal function. The serum half-life was reduced from 23.55 h in the interdialysis periods to 3.40 h during the dialysis sessions. The average extraction coefficient was 0.249. It is recommended that a 500 mg dose cefroxadine should be administered at the end of each dialysis session if the interdialysis period is 48 h.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Geriatric nephrology and urology 5 (1995), S. 93-96 
    ISSN: 1573-7306
    Keywords: free radicals ; age ; hemodialysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A prospective study of 32 patients on periodic hemodialysis for at least 6 months, clinically stable and with parameters of adequate dialysis (KTV〉1.2; PCR 〉 1) was made. Patients, all of them dialyzed with cuprophan, were divided into two groups, depending on whether they were younger or older than 65. Venous blood samples were obtained at the beginning of hemodialysis and sequentially along the dialytic session, processed immediately to determine the production of free radicals with and without stimulation with phorbol myristate acetate (PMA). Free radicals production increases during the period of dialysis in both groups, although in old patients reached statistically significantly higher values than in the younger group.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1435-4373
    Keywords: Key words HIV-1 infection ; Chronic viral hepatitis ; Hepatitis C virus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The aims of this study were to analyze the mortality directly attributable to chronic viral hepatitis in HIV-1 infected patients and to investigate the influence of hepatitis virus infections on the survival of this population. A cohort of 328 HIV-1 infected, antiretroviral-treated patients, followed up from 1989 to 1996, was investigated in the study. The median follow-up period of the cohort was 120 weeks. The median baseline CD4+ cell count of the cohort was 303 cells/mm3. Hepatitis C virus, hepatitis B virus and hepatitis D virus infections were present in 214 (65%), 16 (4.9%) and 9 (2.7%) patients, respectively. Sixty-seven (20.4%) subjects died but there was no information on the vital status of 36 patients (11%). The causes of mortality were AIDS in 49 (73%), liver failure in 3 (4.5%) and other causes in 15 (22.4%). The cohort was divided into two groups for survival analysis, the groups consisting of persons infected by a hepatitis virus and persons without hepatitis virus infection. There was no difference in survival between the two groups (p=0.31, log-rank). It is concluded that mortality among HIV-1/hepatitis virus coinfected patients with moderate to severe immunosuppression is mostly due to AIDS, and that the survival of these subjects is not influenced by the presence of hepatitis virus infections, particularly hepatitis C virus.
    Type of Medium: Electronic Resource
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