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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of medicine & science in sports 3 (1993), S. 0 
    ISSN: 1600-0838
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Sports Science
    Notes: During one year 4398 injured athletes were treated at the casualty wards of Aarhus, Denmark; 156 were practicing track and field disciplines. In the same period 54 track athletes of a Danish sport club were followed in order to register any lesion incurred during sports activity. Thirty-one athletes (57%) had 35 injuries, giving an injury incidence of 1.8 per 1000 hours of practice. At follow-up after 1 year, 13% of all athletes still had complaints, and none of them had returned to former sports activity. Jumpers had overuse symptoms correlated to take-off, and sprains or fractures related to downstrokes. Runners had a higher risk of overuse injuries than jumpers, especially involving the Achilles tendon and the plantar aponeurosis. Young athletes had a higher injury incidence per time than older participants; and women had higher injury risk than men.
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  • 2
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Fourty-three patients with oral mucosal lesions were divided into 3 groups based on the relationship between lesions and amalgam restorations. Group I consisted of patients with contact lesions confined to mucosal areas in contact with amalgam fillings. Group II patients had lichen planus lesions exceeding the area of contact with an amalgam filling and Group III comprised patients with lichen planus lesions without relation to amalgam fillings. Biopsies were embedded in epon and subjected to autometallography in order to demonstrate a possible accumulation of mercury in the affected mucosa. In 20 our of 21 patients in Group I, 4 of 11 patients in Group II and 4 of 11 patients in Group III, mercury was found in the lysosomes of macrophages and fibroblasts. In Group I the number of celles loaded with mercury was much higher than in Group II and in particular Group III. In the latter groups autometallographically demonstrated mercury was found almost exclusively in macrophages. Nineteen biopsies taken from patients with normal mucosa served as controls. Ten had occlusal (Group IV) and seven buccal fillings (Group V). The biopsies from the latter group were taken from areas opposing amalgam restorations. Two patients had no amalgam fillings (Group VI). The histochemical technique showed that three biopsies in Group IV (occlusal fillings only) and two in Group V (opposing buccal fillings) contained traces of mercury in the juxtaepithelial connective tissue. The silver enhanced mercury was found in macrophages. The two controls (Group VI) without amalgam fillings were devoid of precipitates. Thus, the present study documents for the first time 1) that mercury is taken up by the lesioned oral mucosal membrane, 2) that under certain, at present unknown, conditions mercury can also penetrate the intact oral mucosa without causing clinical or histopathologic changes.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Rheumatology international 7 (1987), S. 47-48 
    ISSN: 1437-160X
    Keywords: Gold toxicology ; Human liver, hepatocytes ; Human placenta, fibroblasts ; Lysosomes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    International journal of legal medicine 97 (1986), S. 141-146 
    ISSN: 1437-1596
    Keywords: Alcohol and violence ; Violence, influence of alcohol ; Alkoholeinfluß und Gewaltkriminalität ; Wochenendkriminalität
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Description / Table of Contents: Zusammenfassung Über einen Zeitraum von 1 Jahr wurden alle Fälle von Gewalttätigkeit (n=1639) in einem genau definierten Gebiet registriert. In 488 Fällen (29%) wurden positive Alkoholtests (‰〉0,2) festgestellt. Weitere 216 Patienten (13%) standen nach klinischer Beurteilung unter Alkoholeinfluß. In neun von zehn Fällen von Totschlag und Mord war Alkoholeinfluß festzustellen. Junge Männer im Alter von 19–29 Jahren bildeten einen hohen Anteil unter den Opfern. Sechsundsechzig Prozent der Gewalttätigkeiten ereigneten sich am Wochenende. In 250 Fällen lag die Alkoholkonzentration über 1,5‰. Fünfzig Prozent der Fälle von Gewaltanwendung geschahen in oder in der Nähe von Gaststätten. Stumpfe Gewalt betraf 73% der Fälle. Schußwaffengebrauch war in fünf und scharfe Gewalt in zwei Fällen festzustellen.
    Notes: Summary All cases of assaults with violence (n=1639) from a well defined area were registered for 1 year. A positive alcolmeter test (‰〉0.2) was registered in 488 cases (29%). A further 216 patients (13%) were found under the influence of alcohol according to a simple clinical judgment. In nine of ten manslaughter and murder cases alcohol was involved. Young men, 19–29 years of age, comprised the majority of victims. Of the episodes of violence 66% took place during the weekend. In 250 cases the alcohol concentration surpassed 1.5‰. Almost 50% of the violence episoded took place in or around restaurants. Blunt violence was concerned in 73% of the episodes. Gunshot was registered in five cases, stabbings in two cases.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1434-0879
    Keywords: Benign prostatic hypertrophy ; Age ; Symptoms ; Urodynamics ; Cystoscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To evaluate influence of age on symptomatology and objective parameters in benign prostatic hypertrophy, preoperative findings in 199 unselected patients during one year were analysed. Symptoms of bladder instability increased with age, as did incidence of uninhibited detrusor contractions and bladder trabeculation, whereas maximum urine flow and obstructive complaints decreased, although prostatic size was the same. In the oldest age groups only was increasing prostatic size associated with increasing bladder trabeculation. Age related changes in neurological control and in the structure of the bladder may be involved, and the present results suggest age to be an important factor in the interpretation of symptoms and objective findings in prostatic hypertrophy.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 81 (1991), S. 434-442 
    ISSN: 1432-0533
    Keywords: Rats ; Spinal cord ; Mercuric chloride ; Autometallography ; Lysosomes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The autometallographic method has been used in conjunction light and electron microscopy to determine the exact localization of mercury in the rat spinal cord. Adult male Wistar rats were treated intraperitoneally with accumulative doses of mercuric chloride (100–200 μg HgCl2 daily). Transverse sections of the first cervical segment (C1), fifth cervical segment (C5), sixth thoracic segment (T6), and first lumbar segment (L1) of the spinal cord were examined. The distribution pattern of mercury was dose dependent. In ventral horn motoneurons and neurons of nucleus dorso-medialis (C1) pronounced staining was found after a total dosage of 1200 μg HgCl2. In nucleus intermedio-lateralis (T6, L1) and nucleus cervicalis centralis (C1) stained neurons were first seen after 2600 μg HgCl2. Ultrastructurally, mercury deposits were exclusively located in lysosomes of neurons, astrocytes, endothelial cells, and ependymal cells.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Histochemistry and cell biology 81 (1984), S. 283-285 
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Rats were treated intraperitoneally with the gold-containing compounds sodium aurothiomalate (Myocrisin), sodium aurothiosulfate (Sanocrysin), and aurothioglucose. Using stem energy dispersive X-ray analysis, gold and silver were shown to be located at the same point in lysosomes of proximal tubular cells of the kidney, in hepatocytes and in macrophages of lymph glands, spleen and liver. This result indicates that, after exposure to ultraviolet radiation, chemically bound tissue gold is transformed to metallic gold that subsequently can catalyze the reduction of silver ions to silver when subjected to physical development, i.e. exposed to a photographic developer containing silver ions in addition to the reducing molecules.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Archives of toxicology 66 (1992), S. 79-89 
    ISSN: 1432-0738
    Keywords: Mercury vapor ; Autometallography ; Rats ; Central nervous system ; Lysosomes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The autometallographical technique has been used to determine the distribution and cellular localization of mercury deposits in the Wistar rat CNS after exposure to elemental mercury vapor (50–550 μg Hg/m3 of air for 4–24 h). In animals exposed to 50 μg Hg/m3 for 8 h, silver-enhanced mercury grains were confined to the capillary walls. Increasing the concentration of mercury to 500 μg Hg/m3 caused mercury staining to appear in neurons in the corpus striatum, mesencephalic nucleus of the trigeminal nerve and cerebellar deep nuclei. In the spinal cord, mercury appeared primarily in the motoneurons of lamina IX. Following exposure to 550 μg Hg/m3 for 12 h mercury was additionally detected in the ependyma. Animal exposure to 550 μg Hg/m3 for 24 h resulted in visible mercury deposits in the cerebellar and cerebral cortices. In the cerebral cortex, mercury was present in neurons populating lamina III in the isocortex. No mercury was detected in the allocortex. In the cerebellar cortex, mercury staining was limited to the Purkinje cells. Neurons in the thalamus contained heavy accumulations of mercury. Heavy staining for mercury was detected in lung alveolar macrophages in sections prepared from animals exposed to 550 μg Hg/m3 for 24 h. In animals exposed to 500 μg Hg/m3 or more, the primary target cells were the neurons, but glia cells also contained scattered mercury deposits. Ultrastructurally, mercury deposits were detected in the lysosomes.
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  • 9
    ISSN: 1573-6865
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The autometallographic technique was used to demonstrate the localization of mercury in dorsal root ganglia of adult Wistar rats. The animals were either exposed to mercury vapour, 100 μg Hg m−3, 6 h day−1, 5 days per week, or treated with organic mercury in the drinking water, 20 mg CH3HgCl per litre, for 4 weeks. The effect of orally administered sodium selenite on the pattern of intracellular distribution of mercury in these two situations was investigated. In rats exposed to mercury vapour alone, faint staining was present in ganglion cells. The selenite induced a conspicuous incre ase in the number of stained cells and in the intracellular staining intensity. In rats treated with organic mercury, mercury deposits were detected within ganglion cells and macrophages. The number of mercury-containing cells was increased by co- administration of selenite. In addition, satellite cells, the capsule and vessel walls were faintly stained. Twenty weeks after cessation of the organic mercury treatmen t, mercury staining was reduced. Again, selenite treatment enhanced staining intensity. When studied using the electron microscope, mercury was restricted to lysosomes, irrespective of treatments. The present study shows that the deposition of autometallographic mercury in the dorsal root ganglia depends on the chemical type of mercury, the co-administration of selenite and the length of the survival period.
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