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  • 1
    Electronic Resource
    Electronic Resource
    Phase contrast magnetic resonance of the spinal cord preliminary results in spinal cord arterio-venous malformations (1993)
    Springer
    Acta neurochirurgica 123 (1993), S. 57-63 
    Details
    ISSN: 0942-0940
    Keywords: Magnetic resonance imaging ; angio MR ; phase contrast magnetic resonance ; spinal cord arteriovenous malformations
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In spite of the recent advances in neuroradiology including the CT scan and the spin-echo-magnetic resonance (MR), accurate diagnosis of arteriovenous malformations (AVMs) involving the spinal cord is still based on selective angiography. This last procedure is invasive and needs to be repeated during the follow up. Phase contrast angio MR was performed with a 0.5 Tesla unit on 12 patients with an AVM involving the spinal cord (7 intramedullary AVMs, 4 perimedullary fistulas, and 1 dural fistula with perimedullary venous drainage); 4 of these were investigated before and after treatment. Angio MR showed abnormal vascular patterns within the spinal canal in all cases, without distinguishing between arteries and veins; the nidus of the intramedullary AVMs was displayed in all cases. Angio MR provided images of the whole AVMs comparable to the angiographic pictures, in contrast to the spin-echo MR, which provided only discontinued images of the vessels. The efficient range of velocity providing images varied, according to the type of the malformation (slow for dural fistulas, rapid for intra-medullary AVMs). In the 4 patients investigated after treatment, comparison of the images obtained before and after treatment permitted assessment of the degree of occlusion of the malformation. Finally, angio MR as a complement of spin-echo MR can now be used as a reliable tool for detection of spinal cord AVMs, assessing the indication for angiography, and, furthermore, it can probably replace most of the postoperative control angiographies. The value of the efficient imaging velocity is disputable but seems to depend on the haemodynamic characteristics of the malformation and may then serve as a guide to angiography.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01476287
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  • 2
    Electronic Resource
    Electronic Resource
    Oblique transcorporeal approach to anteriorly located lesions in the cervical spinal canal (1993)
    Springer
    Acta neurochirurgica 121 (1993), S. 187-190 
    Details
    ISSN: 0942-0940
    Keywords: Cervical spine ; surgical technique ; transcorporeal approach ; vertebral artery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The technique of obliquely drilling out the postero-lateral part of the cervical vertebral bodies is described. It uses the antero-lateral (retro carotico-jugular) approach to control and displace the vertebral artery postero-laterally and to expose the lateral aspect of the vertebral bodies. It provides, through a wide field and with minimal retraction of the carotid artery and the internal jugular vein, an extensive view of the anterior aspect of the spinal cord. It has already been used to treat 15 anterior lesions compressing the spinal cord including neurinomas and osteophytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01809273
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  • 3
    Electronic Resource
    Electronic Resource
    Pyogenic parenchymatous and nidus infection after embolization of an arteriovenous malformation (1993)
    Springer
    Acta neurochirurgica 122 (1993), S. 130-133 
    Details
    ISSN: 0942-0940
    Keywords: Arterio-venous malformations ; embolization ; infectious complications ; brain abscess ; angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Infectious complications of cerebral angiography and of therapeutic angiographic procedures are very seldom reported. The case of an infected embolized arteriovenous malformation (AVM) by staphylococcus aureus is reported. Abscess formation became manifest seven months after the endovascular procedures. Antibiotherapy was initially started after puncturing the abscess, but finally the cure of the lesion could only be obtained by radical excision of the infected and embolized AVM, as if the persisting embolization material was promoting the infection. The modalities of infection after cerebral endovascular procedures are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01447000
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  • 4
    Electronic Resource
    Electronic Resource
    The Extent of Drilling in Lateral Approaches to the Cranio-Cervical Junction Area from a Series of 125 Cases (1999)
    Springer
    Acta neurochirurgica 141 (1999), S. 111-118 
    Details
    ISSN: 0942-0940
    Keywords: Keywords: Cranio-cervical junction; foramen magnum; lateral approaches; occipital condyle.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary  The trans-condylar approach to the craniocervical junction area (CCJA) requires a more or less extensive drilling of the two first cervical joints (C0–C1 and C1–C2). The extent of drilling necessary to resect a lesion at the CCJA was analyzed from a series of 125 cases including 114 tumours and 11 non-tumoural processes treated using a lateral approach (postero-lateral or antero-lateral) over a 15-year period (1980–1995)  The extent of drilling was estimated on CT scanner axial views from the reduction of the joints surface and three groups were determined: A/less than one third B/between one third and one half, and C/more than one half. The extent of drilling was compared with the lesion location in relation to the bone limits of the CCJA: within these limits, outside them and into the bony structures. It was also analyzed with regard to pathology when separated into three groups: non-osseous tumours, osseous tumours and chordomas, and non-tumoural processes.  Only 26 cases had a significant drilling, i-e more than one third of the joint surfaces and of these, 14 were more than one half. In all these 14 cases, the bone structures were already invaded and 13 of them were, to some extent, beyond the bone limits of the CCJA. Of the 12 cases with drilling between one third and one half, 11 involved the bone structures and 1 was located inside the CCJA bone limits. Drilling of more than one third was required only in the case of bone lesions: 10 out of 23 bone tumours, all the 14 cases of chordomas, one case of rheumatoïd arthritis and one case of C1–C2 joint spondylosis. In the other cases including mostly non-osseous tumours, drilling was limited to less than one third, though a high rate of complete removal was achieved (98%). Stabilization by arthrodesis with posterior grafting (N=10) or by lateral bone grafting (N=5) was achieved in all cases involving more than one half drilling, and in one case of tuberculosis.  By adequately choosing the surgical approach, the extent of drilling can always be minimal. Extensive bone resection is only necessary when the tumour has already destroyed the joints. In that case, lateral or posterior fusion is an efficient technique.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007010050274
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  • 5
    Electronic Resource
    Electronic Resource
    Combined Management of Intracranial Aneurysms by Surgical and Endovascular Treatment. Modalities and Results from a Series of 395 Cases (1999)
    Springer
    Acta neurochirurgica 141 (1999), S. 557-562 
    Details
    ISSN: 0942-0940
    Keywords: Keywords: Aneurysms; embolization; Guglielmi detachable coil; clinical outcome.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary  The selective occlusion of saccular intracranial aneurysms may be achieved by two techniques: microsurgical clipping and endovascular coiling. Each of them have particular indications which need to be defined. We report on a series in which both techniques were applied.  From September 1992 to June 1996, 395 consecutive patients with small or large aneurysm were treated either by surgery (N=102) or by endovascular coiling (N=293). Coiling was chosen each time the shape of the aneurysm seemed to be appropriate for this treatment: narrow neck and ratio neck diameter by sac diameter less than one third.  Satisfactory results with complete or subtotal obliteration and no recanalization on the following controls at 1, 6, 12 and 36 months, were obtained in 92% before retreatment and in 98.8% after retreatment. Unsatisfactory results were observed after surgery in 7 cases and in 25 cases after embolization. After retreatment, it remains 3 post-surgical and 2 post-endovascular cases.  In the overall series, good and excellent clinical outcome was noted in 90% for small aneurysms and in 86.5% for large ones; mortality was of 4.8%.  In a series in which were applied both types of treatment, surgery in 25% and endovascular technique in 75%, good results in terms of aneurysm occlusion and clinical results were achieved. These results are as good as the best series in which surgery was the only choice. Therefore with appropriate selection, endovascular treatment is a good alternative for treatment of the majority of saccular aneurysms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007010050343
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  • 6
    Electronic Resource
    Electronic Resource
    Arteriovenous malformations of the posterior fossa (1992)
    Springer
    Acta neurochirurgica 116 (1992), S. 119-127 
    Details
    ISSN: 0942-0940
    Keywords: Arteriovenous malformation ; cavernous angioma ; MRI ; surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary AVMs of the posterior fossa are reviewed on the basis of personal experience of 47 cases including 2 venous angiomas, 7 cavernous angiomas, 5 arteriovenous fistulas and 33 true arteriovenous malformations and of the few series reported in the literature. MRI is now an indispensable tool to define the exact localization of any malformation. Combined with angiography, it permits one to choose the most adequate therapeutic strategy and the best surgical approach. Radical cure is to be contemplated in most cases considering the often dramatic consequences of bleeding at the infratentorial level. Deep AVMs and moreover cavernous angiomas, even those located in highly functional structures such as the brain stem, can now be discussed for treatment. Encouraging results have already been obtained using, alone or in association, the recently advanced modalities of treatment: interventional neuroradiology, radiosurgery, and microsurgery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01540864
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  • 7
    Electronic Resource
    Electronic Resource
    AC/GT and AG/CT microsatellite repeats in peach [Prunus persica (L) Batsch]: isolation, characterisation and cross-species amplification in Prunus (1999)
    Springer
    Theoretical and applied genetics 99 (1999), S. 65-72 
    Details
    ISSN: 1432-2242
    Keywords: Key words Simple sequence repeat (SSR) ; Microsatellites ; Molecular markers ; Genetics ; Fingerprinting
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  We report the sequences of 17 primer pairs of microsatellite loci, which we have cloned and sequenced from two genomic libraries of peach [Prunus persica (L) Batsch] ‘Redhaven’, enriched for AC/GT and AG/CT repeats respectively. For ten of these microsatellite loci we were able to demonstrate Mendelian inheritance in a segregating back-cross population; the remainder did not segregate. The polymorphism of the microsatellites was evaluated in a panel of ten peach genotypes, including true-to-type peaches, nectarines and one canning-peach. Fifteen microsatellites (88%) were polymorphic showing 2–4 alleles each. The mean heterozygosity, averaged over all loci, was 0.32 and significantly higher than that reported in the literature for isozymes and molecular markers, such as RFLPs and RAPDs. We have also assayed the cross-species transportability and found that ten microsatellite (59%) gave apparently correct amplification in all Prunus species surveyed, namely P. domestica (European plum), P. salicina (Japanese plum), P. armeniaca (apricot), P. dulcis (almond), P. persica var. vulgaris (peach), P. persica var. laevis (nectarine), P. avium (sweet cherry) and P. cerasus (sour cherry), with three of them also being amplified in Malus (apple). The remaining microsatellites gave less-extensive amplification. Because of their appreciable polymorphism and wide cross-species transportability, most of these new markers can be integrated into the linkage maps which are currently being constructed in peach, as well as in other stone fruit crops, such as almond, apricot, cherry and plum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001220051209
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