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  • 1
    Publication Date: 2022-10-05
    Description: The spatial and angular emission patterns of artificial and natural light emitted, scattered, and reflected from the Earth at night are far more complex than those for scattered and reflected solar radiation during daytime. In this commentary, we use examples to show that there is additional information contained in the angular distribution of emitted light. We argue that this information could be used to improve existing remote sensing retrievals based on night lights, and in some cases could make entirely new remote sensing analyses possible. This work will be challenging, so we hope this article will encourage researchers and funding agencies to pursue further study of how multi‐angle views can be analyzed or acquired.
    Description: Plain Language Summary: When satellites take images of Earth, they usually do so from directly above (or as close to it as is reasonably possible). In this comment, we show that for studies that use imagery of Earth at night, it may be beneficial to take several images of the same area at different angles within a short period of time. For example, different types of lights shine in different directions (street lights usually shine down, while video advertisements shine sideways), and tall buildings can block the view of a street from some viewing angles. Additionally, since views from different directions pass through different amounts of air, imagery at multiple angles could be used to obtain information about Earth's atmosphere, and measure artificial and natural night sky brightness. The main point of the paper is to encourage researchers, funding agencies, and space agencies to think about what new possibilities could be achieved in the future with views of night lights at different angles.
    Description: Key Points: Remote sensing using the visible band at night is more complex than during the daytime, especially due to the variety of artificial lights. Views of night lights intentionally taken from multiple angles provide several advantages over near‐nadir or circumstantial view geometries. Night lights remote sensing would benefit from greater consideration of the role viewing geometry plays in the observed radiance.
    Description: EC H2020 H2020 Societal Challenges http://dx.doi.org/10.13039/100010676
    Description: Helmholtz Association http://dx.doi.org/10.13039/501100009318
    Description: Slovak Research and Development Agency
    Description: Xunta de Galicia (Regional Government of Galicia) http://dx.doi.org/10.13039/501100010801
    Description: National Aeronautics and Space Administration http://dx.doi.org/10.13039/100000104
    Description: University of Hong Kong http://dx.doi.org/10.13039/501100003803
    Description: Fonds de recherche du Québec
    Description: EC Emprego, Assuntos Sociais e Inclusão European Social Fund http://dx.doi.org/10.13039/501100004895
    Description: Natural Environment Research Council http://dx.doi.org/10.13039/501100000270
    Description: City of Cologne, Germany
    Keywords: ddc:551.5
    Language: English
    Type: doc-type:article
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  • 2
    Publication Date: 2013-01-17
    Description: [1]  Different turbulent entrainment-mixing processes (e.g., homogeneous and inhomogeneous) occur in clouds; accurate representation of these processes is critical for improving cloud-related parameterizations in large-scale models, but poorly understood and quantified. Using in situ aircraft observations over the U. S. Department of Energy's Atmospheric Radiation Measurement Southern Great Plains site during the March 2000 Cloud Intensive Observation Period and numerical simulations with the Explicit Mixing Parcel Model (EMPM), here we explore the potential of using degree of homogeneous mixing as a measure to quantify these different mechanisms and examine various microphysical measures of homogeneous mixing degree and their relationships to entrainment-mixing dynamics as measured by transition scale numbers. Three different microphysical measures for the homogeneous mixing degree are newly defined and each is coupled with one of two different transition scale numbers. Both observations and simulations show that all the combinations have positive correlated relationships; simulations further show that the tightest relationship is between the measure of homogeneous mixing degree considering adiabatic number concentration and the transition scale number accounting for mixing fraction of dry air. A parameterization of the entrainment-mixing processes is advanced according to the relationships of homogeneous mixing degree measures to transition scale numbers.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
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  • 3
    Publication Date: 2014-11-22
    Description: This work empirically examines the dependence of entrainment-mixing mechanisms on the averaging scale in cumulus clouds using in situ aircraft observations during the RACORO field campaign. A new measure of homogeneous mixing degree is defined that can encompass all types of mixing mechanisms. Analysis of the dependence of the homogenous mixing degree on the averaging scale shows that, on average, the homogenous mixing degree decreases with increasing averaging scales, suggesting that apparent mixing mechanisms approach gradually from homogeneous mixing to extreme inhomogeneous mixing with increasing scales. The scale dependence can be well quantified by an exponential function, providing first attempt at developing a scale-dependent parameterization for the entrainment-mixing mechanism. Further examined are the influences of three factors on the scale dependence: droplet-free filament properties (size and fraction), microphysical properties (mean volume radius and liquid water content of cloud droplet size distributions adjacent to droplet-free filaments), and relative humidity of entrained dry air. It is found that the decreasing rate of homogeneous mixing degree with increasing averaging scales becomes larger with larger droplet-free filament size and fraction, larger mean volume radius and liquid water content, or higher relative humidity. The results underscore the necessity and possibility of considering averaging scale in representation of entrainment-mixing processes in atmospheric models.
    Print ISSN: 0148-0227
    Topics: Geosciences , Physics
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  • 4
    Publication Date: 2014-01-04
    Description: Background: Hylocereus polyrhizus and Hylocereus undatus are two varieties of the commonly called pitaya fruits, and pitaya fruits have gained popularity in many countries all over the world. However, studies on chemical composition and the nutritional quality of pitaya flesh peel are limited. Results: Extracts of pitaya (H. polyrhizus and H. undatus) peel were extracted by supercritical carbon dioxide extraction, and analyzed by gas chromatography-mass spectrometry analysis. Their cytotoxic and antioxidant activities were investigated. The main components of H. polyrhizus extract were beta-amyrin (15.87%), alpha-amyrin (13.90%), octacosane (12.2%), gamma-sitosterol (9.35%), octadecane (6.27%), 1-tetracosanol (5.19%), stigmast-4-en-3-one (4.65%), and campesterol (4.16%), whereas H. undatus were beta-amyrin (23.39%), gamma-sitosterol (19.32%), and octadecane (9.25%), heptacosane (5.52%), campesterol (5.27%), nonacosane (5.02%), and trichloroacetic acid, hexadecyl ester (5.21%). Both of the two extracts possessed good cytotoxic activities against PC3, Bcap-37, and MGC-803 cells (IC50 values ranging from 0.61 to 0.73 mg/mL), and the activities of their main components were also studied. Furthermore, these extracts also presented some radical scavenging activities, with IC50 values of 0.83 and 0.91 mg/mL, respectively. Conclusion: This paper provides evidence for studying the chemical composition of supercritical carbon dioxide extracts of pitaya peel and their biological activity.
    Electronic ISSN: 1752-153X
    Topics: Chemistry and Pharmacology
    Published by Chemistry Central
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  • 5
    Publication Date: 2016-01-06
    Description: Recent investigations have highlighted that therapeutic artificial microRNAs could be promising candidates for cancer therapy through the modulation of tumor promoter or suppressor. MEK kinase 1 (MEKK1) is expressed by mitogen-activated kinase kinase kinase 1 (MAP3K1), an important kinase that links Ras activation to MAPK signaling. In the present study, we showed that synthetic MAP3K1-targeting artificial miRNA may provide considerable beneficial effects in the prevention of breast cancer growth and metastasis. We showed that MEKK1 was highly expressed in human breast cancer specimens, compared with adjacent normal tissues. Using a miRNA-expressing lentivirus system, we delivered a artificial miRNA (Map3k1 amiRNA) that targets MAP3K1 into 4T1 breast cancer cells and investigated the impact of MAP3K1-targeting miRNA on the growth and invasive behavior of breast cancer in vitro and in vivo. We found that overexpression of Map3k1 amiRNA led to impaired activities of p-ERK and p-p38. In addition, Map3k1 amiRNA induced marked proliferative impairment and invasive attenuation in breast cancer cells. However, Map3k1 amiRNA did not have evident influence on the apoptotic response of 4T1 cells. Moreover, using in vivo nude mice model, we identified that Map3k1 amiRNA attenuated tumor growth and lung metastasis of breast cancer cells. Taken together, our findings explicitly indicated that MEKK1 exerted important oncogenic property in breast cancer development, and MAP3K1-targeting artificial miRNA may provide promising therapeutic effects in the treatment of breast cancer.
    Electronic ISSN: 2193-1801
    Topics: Natural Sciences in General
    Published by SpringerOpen
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  • 6
    Publication Date: 2013-04-05
    Description: [1]  The relationships between fractional entrainment rate and key microphysical quantities (e.g., liquid water content, droplet number concentration, volume-mean radius, standard deviation of cloud droplet size distributions) in shallow cumuli are empirically examined using in situ aircraft observations from the RACORO field campaign over the ARM SGP site. The result shows that the microphysical quantities examined generally exhibit strong relationships with entrainment rate, and that the relationships collectively suggest the dominance of homogeneous entrainment mixing, which is unfavorable to the formation of large droplets and the initiation of warm rain in these clouds. The dominance of the homogeneous mixing mechanism is further substantiated by the dependency on entrainment rate of relationships among various microphysical variables and of cloud droplet size distributions. The dominance of homogeneous mixing mechanism is also quantitatively confirmed by examining the degree of homogeneous mixing in these clouds. The dominance of homogeneous mixing may be an important reason why none of these cumulus clouds were drizzling.
    Print ISSN: 0094-8276
    Electronic ISSN: 1944-8007
    Topics: Geosciences , Physics
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  • 7
    Publication Date: 2012-11-08
    Description: The simultaneous measurements of vertical velocity and cloud droplet size distributions in cumuli collected during the RACORO field campaign over the Atmospheric Radiation Measurement Program's Southern Great Plains site near Lamont, Oklahoma, US, are analyzed to determine the effects of vertical velocity on droplet number concentration, relative dispersion (the ratio of standard deviation to mean radius), and their relationship. The results show that with increasing vertical velocity the droplet number concentration increases while the relative dispersion decreases. The data also exhibit a negative correlation between relative dispersion and droplet number concentration. These empirical relationships can be fitted well with power law functions. This observational study confirms the theoretical and numerical expectations of the effects of vertical velocity on cloud microphysics by analyzing the data of vertical velocity directly. The effects of vertical velocity on relative dispersion and its relationship with droplet number concentration are opposite to that associated with aerosol loading, posing a confounding challenge for separating aerosol indirect effects from dynamical effects.
    Print ISSN: 0094-8276
    Electronic ISSN: 1944-8007
    Topics: Geosciences , Physics
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  • 8
    Publication Date: 2012-10-30
    Description: Entrainment processes in convective clouds often occur stochastically and entrainment rate estimates depend on the distance from the cloud from which the dry air is entrained. However, no observational studies exist on either the distance dependence or probability density function of entrainment rate, hindering understanding and the parameterization of convection. Here entrainment rate in cloud cores is estimated using a recently developed mixing fraction approach that is applied to in situ aircraft measurements of cumuli from the RACORO field program. The results are used to examine, for the first time, probability density functions of entrainment rate and their dependence on the distance from the edge of the cloud core from which the dry air is entrained. The estimated entrainment rate decreases when the dry air is entrained from increasing distance from the edge of the cloud core; this is because the air farther from the edge of the cloud core is drier than the neighboring air that is within the humid shell around the cumulus cloud core. Probability density functions of entrainment rate vary with the distance and height above the cloud-base, and all are well fitted by lognormal distributions. The implications of the results for convection parameterizations are discussed.
    Print ISSN: 0094-8276
    Electronic ISSN: 1944-8007
    Topics: Geosciences , Physics
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