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  • 1
    Electronic Resource
    Electronic Resource
    Moessbauer spectroscopy of organometallic compounds. Alkyl- and aryltin cyanates and related molecules (1971)
    s.l. : American Chemical Society
    Inorganic chemistry 10 (1971), S. 1020-1025 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic50099a033
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  • 2
    Electronic Resource
    Electronic Resource
    Proposed structure of bis(tri-n-butyltin) sulfate and related molecules (1970)
    s.l. : American Chemical Society
    Inorganic chemistry 9 (1970), S. 970-972 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic50086a059
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Laparoscopic-assistedvs. open surgery for colorectal cancer (1998)
    Springer
    Diseases of the colon & rectum 41 (1998), S. 901-909 
    Details
    ISSN: 1530-0358
    Keywords: Colorectal cancer ; Laparoscopic surgery ; Immune response
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract PURPOSE: Our aim was to test the hypothesis that laparoscopic-assisted resection for colorectal cancer has an immunologic advantage over traditional open surgery. METHODS: Sixteen patients with colorectal cancer were randomized to undergo laparoscopic-assisted resection or open surgery. Basic patient data were recorded, and serum interleukin-6 levels, relative proportions of lymphocytes, and human leukocyte antigen-DR expression on monocytes were determined at specific time intervals. RESULTS: Operating time was longer for laparoscopic-assisted resection (P=0.02), but analgesic requirements were less (P=0.04). All patients exhibited the following: interleukin-6 levels increased to a maximum at 4 hours and returned to preoperative levels within 48 hours. This response appeared greater for open resection (mean peak level, 313vs. 173 pg/ml;P=0.25). Relative granulocytosis (P〈0.001) was seen within 48 hours, which was offset by a decrease in percentage of lymphocytes (P〈0.001). Changes in lymphocyte subfractions were most significant seven days post-surgery: natural killer cells decreased (P=0.003); T cells increased (P=0.008), with elevation in the CD4/CD8 ratio (P=0.003). B cells were largely unchanged at all time periods. Human leukocyte antigen-DR expression on monocytes was significantly less at 48 hours postsurgery (P〈0.001). All changes were reversed within three weeks of surgery. There were no differences when comparing laparoscopic-assisted resection with open surgery. CONCLUSIONS: Both laparoscopic-assisted resection and open surgery affect the immune response. It would appear that laparoscopic-assisted resection does not have an immunologic advantage over open surgery in patients with colorectal cancer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02235376
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  • 4
    Electronic Resource
    Electronic Resource
    Laparoscopic-assisted resection of colorectal carcinoma (1999)
    Springer
    Diseases of the colon & rectum 42 (1999), S. 327-332 
    Details
    ISSN: 1530-0358
    Keywords: Laparoscopic assisted ; Colectomy ; Colorectal carcinoma ; Audit
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract INTRODUCTION: The place of laparoscopic-assisted colectomy for colorectal carcinoma is controversial. This study reviewed a consecutive series of patients who underwent laparoscopic-assisted resection of colorectal carcinoma in the past five years. METHODS: Two hundred seventeen laparoscopic-assisted resections of colorectal carcinoma were attempted starting in April 1992. Initially, we only selected patients with metastatic disease or patients who were older than 65 years. Subsequently, both palliative and curative resections were attempted in patients with a suitable tumor, with no age limitation. Thus, all suitable patients were randomly assigned to received either laparoscopic-assisted or conventional open surgery. RESULTS: Data collection was completed in 201 patients. In 22 patients open surgery was performed after a diagnostic laparoscopy. In the remaining 179 patients (90 males) in whom laparoscopic dissection was actually performed, the mean follow-up was 19.8 months, and the mean age was 66.3 years. The procedures performed included right hemicolectomy or extended right hemicolectomy (30 patients), transverse colectomy (2 patients), left hemicolectomy (3 patients), sigmoidectomy (48 patients), anterior resection (59 patients), and abdominoperineal resection (37 patients). Thirty-two (17.7 percent) procedures were converted to open surgery. The mean operation time was 203 minutes. The median blood loss was negligible, and the median requirement of transfusion was zero. The median number of postoperative parenteral analgesic injections was three. The median time to resume diet and hospital discharge were four and six days, respectively. The operative mortality was 1.7 percent. The survival rates at four years were 100, 88.3, and 64.5 percent for patients with Dukes A, B, and C disease, respectively. There was only one (0.65 percent) port-site recurrence. CONCLUSION: Laparoscopic-assisted resection of colorectal carcinoma was technically feasible and safe. It allowed early postoperative recovery with satisfactory long-term survival. This is at the expense of a long operation. Its benefits over the conventional open technique await the results of the randomized trials.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02236347
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  • 5
    Electronic Resource
    Electronic Resource
    Invited editorial (1999)
    Springer
    Diseases of the colon & rectum 42 (1999), S. 332-333 
    Details
    ISSN: 1530-0358
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02236348
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  • 6
    Electronic Resource
    Electronic Resource
    Laparoscopic resection of splenic artery aneurysm (1998)
    Springer
    Surgical endoscopy and other interventional techniques 12 (1998), S. 53-53 
    Details
    ISSN: 1432-2218
    Keywords: Key words: Splenic artery aneurysm—Laparoscopic ligation—Lateral position
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. A new, lateral approach was used for the laparoscopic resection of splenic artery aneurysm. This approach was found to be convenient and straightforward.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004649900592
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  • 7
    Electronic Resource
    Electronic Resource
    Laparoscopic-assisted abdominoperineal resection for low rectal adenocarcinoma (2000)
    Springer
    Surgical endoscopy and other interventional techniques 14 (2000), S. 67-70 
    Details
    ISSN: 1432-2218
    Keywords: Key words: Abdominoperineal resection — Adenocarcinoma — Rectal adenocarcinoma — Colorectal surgery — Rectum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Background: Laparoscopic-assisted resection for colorectal lesions is feasible, but most reported series are heterogeneous and noncomparative. The aim of this study was to investigate whether laparoscopic-assisted resection was better than open abdominoperineal resection for low rectal adenocarcinoma. Methods: Twenty-five (study group) of 59 consecutive patients who were considered suitable were selected for laparoscopic-assisted abdominoperineal resection based on the availability of informed consent, laparoscopic instruments, and experienced surgeons. The results in these patients were compared with the other 34 patients operated on by the open method (control group). Results: The median follow-up times for the study and control groups were 30.1 and 28.3 months, respectively. The operation time was significantly longer (t-test, p 〈 0.001), while operative blood loss (Mann-Whitney U test, p= 0.02), postoperative analgesic requirement (Mann-Whitney U test, p= 0.02), time to resume normal diet (Mann-Whitney U test, p= 0.04), and total hospital stay (Mann-Whitney U test, p= 0.02) were significantly less in the study than in the control group. The oncological clearance, complication rate, disease-free interval, and survival were comparable in the two groups. Conclusions: Laparoscopic-assisted abdominoperineal resection allowed earlier postoperative recovery, with equal oncological clearance, morbidity, mortality, disease-free interval, and survival.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004649900014
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