ISSN:
1573-9171
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Conclusions 1. Oxidative cyclization of N-unsubstituted aliphatic thioamides in the Na2S2O8-CuCl2 system leads to 3,5-dialkyl-1,2,4-thiadiazoles in a yield of 50–60%. 2. N-Monoalkyl- and N,N-dialkyl-substituted thioamides quantitatively convert in this system into the corresponding O-amides. 3. The principal difference in the oxidative reactions of aliphatic thioamides and their oxygen analogs in a Na2S2O8-CuCl2 system is determined by the tendency of the S atom of the. thiocarbonyl group to add radicals formed in the oxidation process.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00955376
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