ISSN:
1662-9779
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Physics
Notes:
Crucumin (diferuloylmethane) is a major active component of turmeric, but itsbioavailability of oral administration is very low. In order to improve its pharmaceuticalefficiency in oral use, poly (d,l-lactide) (PDLLA) nanospheres containing curcumin aresuccessfully fabricated using a modified spontaneous emulsification solvent diffusion (SESD)method. The morphology, size and distribution of the resulting nanospheres are characterizedby TEM and laser light scattering method. Drug contents in the nanospheres are calculatedthrough UV spectrophotometer method. As a result, regular spherical PDLLA nanospherescontaining curcumin are obtained and their effective diameters are 289 nm with narrowdistribution (Pd=0.118)
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/02/23/transtech_doi~10.4028%252Fwww.scientific.net%252FSSP.121-123.767.pdf
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