ISSN:
1365-2133
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
Eighty-five patients with widespread psoriasis were treated with daily short-term applications of dithranol and salicylic acid in yellow soft paraffin. Two different schedules were used: (1)‘3-h’ therapy using increasing dithranol concentrations (0.1, 0.25, 0.5, 1, 2%) for 3 h; (2)‘minutes’ therapy using high dithranol concentrations (1, 2, 3%) for only 10–20 min. In comparison with the standard dithranol therapy, applied for 24 h each day, the‘3-h’ therapy showed equal efficacy clinically and histologically, and the‘minutes’ therapy was significantly hotter than the standard therapy, reducing the mean clearing time by 6.8 days. Daily short-term (‘minutes’) therapy combines all the advantages of dithranol with a convenient and readily acceptable mode of application for home use.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1365-2133.1982.tb00922.x
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