Publication Date:
2016-09-23
Description:
Nature Chemistry 8, 958 (2016). doi:10.1038/nchem.2554 Authors: Shigeki Kiyonaka, Ryou Kubota, Yukiko Michibata, Masayoshi Sakakura, Hideo Takahashi, Tomohiro Numata, Ryuji Inoue, Michisuke Yuzaki & Itaru Hamachi The controlled activation of proteins inside living cells is an important goal in protein design research. Now, a strategy for allosteric activation using coordination chemistry has been demonstrated for two different kinds of neurotransmitter receptors, an ion-channel and a G-protein coupled glutamate receptor.
Print ISSN:
1755-4330
Electronic ISSN:
1755-4349
Topics:
Chemistry and Pharmacology
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