Note: General and Synthetic Methods -- Contents -- Chapter 1 Saturated and Unsaturated Hydrocarbons -- 1 Saturated Hydrocarbons -- 2 Olefinic Hydrocarbons -- 3 Stereoselective, Simultaneous Formation of sp3 and sp2 Centres -- Claisen Rearrangements -- [2,3] Wittig Rearrangements -- 4 Conjugated Dienes -- 5 Non-conjugated Dienes -- 6 Polyenes -- 7 Allenes -- 8 Alkynes -- 9 Enynes -- References -- Chapter 2 Aldehydes and Ketones -- 1 Synthesis of Aldehydes and Ketones -- Oxidative Methods -- Reductive Methods -- Methods Involving Umpolung -- Other Methods -- Cyclic Ketones -- 2 Synthesis of Functionalised Aldehydes and Ketones -- Unsaturated Aldehydes and Ketones -- α-Substituted Aldehydes and Ketones -- Dicarbonyl Compounds -- 3 Protection and Deprotection of Aldehydes and Ketones -- 4 Reactions of Aldehydes and Ketones -- Reactions of Enolates -- Aldol Reactions -- Conjugate Addition Reactions -- References -- Chapter 3 Carboxylic Acids and Derivatives -- 1 Carboxylic Acids -- General Synthesis -- Diacids -- Hydroxy-acids -- Keto-acids -- Unsaturated Acids -- Aromatic Acids -- Halo-acids -- Carboxylic Acid Protection -- 2 Carboxylic Acid Esters -- Esterification -- General Synthesis -- Diesters -- Hydroxy-esters -- Keto-esters -- Unsaturated Esters -- Halo-esters -- Thioesters -- 3 Carboxylic Acid Amides -- General Synthesis -- Hydroxy-amides -- Keto-amides -- Unsaturated Amides -- Thioamides -- 4 Lactones -- General Synthesis -- Butyrolactones -- α-Methylene- and α-Alkylidenebutyrolactones -- γ-Alkylidinebutyrolactones -- Butenolides -- Tetronic Acids -- Phthalides -- Valerolactones -- Macrolides -- 5 Amino Acids -- α-Amino acids -- Dehydroamino acids -- Hydroxy α-amino acids -- β-Amino acids -- Amino-acid Coupling -- Amino-acid Protection -- References -- Chapter 4 Alcohols, Halogeno Compounds, and Ethers -- 1 Alcohols -- Preparation. , By Addition to Olefins -- By Reduction of Carbonyl Compounds -- By Nucleophilic Alkylation -- Non Stereoselective Addition -- Selective Addition -- By Opening of Epoxides -- Miscellaneous Methods -- Protection and Deprotection -- Oxidation and Deoxygenation -- 2 Halogeno Compounds -- 3 Ethers and Thioethers -- References -- Chapter 5 Amines, Nitriles, and Other Nitrogen-containing Functional Groups -- 1 Amines -- Acyclic Amines -- Aromatic Amines -- Allylic Amines -- Cyclic Amines -- Protecting Groups -- Enamines -- Alkyldiamines -- 2 Amino-alcohols -- 1,2-Amino-alcohols -- 1,3-Amino-alcohols -- 1,2-Amino-thiols, 1,2-Aminoketones, and α-Aminophosphonic Acids -- Azo Compounds -- Nitriles -- Nitro Compounds -- Nitroxyl and Nitroso Compounds -- Alkyl Nitrates and Nitramines -- Hydroxylamines -- Imines -- Amidines -- Oximes and Hydrazones -- Thiodiimides -- Azides -- Thiocyanates, Isothiocyanates, and Isocyanides -- References -- Chapter 6 Organometallics in Synthesis -- Part I: The Transition Elements -- 1 Introduction -- 2 Reduction -- 3 Oxidation -- 4 Isomerisations and Rearrangements -- 5 Carbon-Carbon Bond-Forming Reactions -- Via Organometallic Electrophiles -- Via Organometallic Nucleophiles -- Via Coupling and Cycloaddition Reactions -- Via Carbonylation Reactions -- 6 Miscellaneous Reactions -- References -- Part II: Main Group Elements -- 1 Group I -- Lithium Amides -- Lithium Enolates -- Non-stabilized Organolithium Reagents -- Lithiated Aromatic and Heteroaromatic Rings -- Benzylic and Allylic Lithium Anions -- Alkenyl and Alkynyl Lithium Anions -- Di- and Trilithiated Anions -- Sodium and Potassium -- Anions Stabilised by Sulphur, Silicon, and Selenium -- 2 Group II -- Magnesium -- Zinc and Mercury -- 3 Group III -- Boron -- Aluminium and Thallium -- 4 Group IV -- Silicon and Germanium. , Allyl, Benzyl, and Alkenyl Silanes and their Derivatives -- Tin and Lead -- 5 Group V -- Phosphorus -- Arsenic, Antimony, and Bismuth -- 6 Group VI -- Sulphur -- Selenium and Tellurium -- References -- Chapter 7 Saturated Carbocyclic Ring Synthesis -- 1 Three-membered Rings -- 2 Four-membered Rings -- 3 Five-membered Rings -- Transition Metal Mediated Cyclisations -- Radical Cyclisations -- Other Routes to Five-membered Rings -- 4 Six-membered Rings -- Diels-Alder Reactions -- Other Routes to Six-membered Rings -- 5 Seven-membered, Medium, and Large Rings -- Seven and Eight-membered Rings -- Large Rings -- Ring Expansions -- References -- Chapter 8 Saturated Heterocyclic Ring Synthesis -- 1 Oxygen-containing Heterocycles -- Three-membered Rings -- Four-membered Rings -- Five-membered Rings -- Tetrahydrofurans -- Dihydrofurans and Benzofurans -- Five-membered Rings with More than One Oxygen -- Six-membered Rings -- Tetrahydropyrans -- Dihydropyrans -- Six-membered Rings with More than One Oxygen -- Medium- and Large-ring Ethers -- 2 Sulphur-containing Heterocycles -- 3 Heterocycles Containing More than One Heteroatom -- Nitrogen- and Oxygen-containing Rings -- Five-membered Rings -- Six- and Seven-membered Rings -- Nitrogen- and Sulphur, and Sulphur- and Oxygen- containing Rings -- 4 Nitrogen-containing Heterocycles -- Three- and Four-membered Rings -- Five-membered Rings -- Six-membered Rings Containing One Nitrogen -- Five- and Six-membered Rings with Two Nitrogen Atoms -- Seven-membered and Larger Rings -- β-Lactam -- References -- Chapter 9 Highlights in the Total Synthesis of Natural Products -- 1 Terpenes -- 2 Alkaloids -- 3 Spiroacetals -- 4 Macrolides -- 5 Polyether Antibiotics -- 6 Tetronolides -- 7 Enediynes -- 8 Other Natural Products -- References -- Chapter 10 Reviews on General and Synthetic Methods. , 1 Saturated and Unsaturated Hydrocarbons -- 2 Halogeno Compounds -- 3 Sulphur Compounds -- 4 Carbonyl Compounds -- 5 Carboxylic Acids and Derivatives -- 6 Carbocyclic Ring Synthesis -- 7 Heterocyclic Ring Synthesis and Alkaloids -- 8 Organometallics -- 9 Asymmetric Synthesis and Stereoselective Processes -- 10 Natural Products Synthesis -- 11 Nucleosides -- 12 Radicals in Synthesis -- 13 Carbohydrates -- 14 Cycloaddition Reactions -- 15 Pressure Reactions -- 16 Photochemistry and Electrochemistry -- 17 General -- Author Index.