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  • 1
    Electronic Resource
    Electronic Resource
    Relationship Between Essential Hypertension and Cognitive Functioning II: Effects of Biofeedback Training Generalize to Non-Laboratory Environment (1977)
    Oxford, UK : Blackwell Publishing Ltd
    Psychophysiology 14 (1977), S. 0 
    Details
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: Eight male essential hypertensives underwent 9 weekly 2-hr biofeedback training sessions in which feedback (i.e., lights and tones) was contingent upon decreases in systolic pressure. Three weekly control sessions (with no feedback) preceded feedback training. Outside the laboratory, patients recorded blood pressure 5 times per day both at home and at work. Patients continued monitoring their blood pressure for up to 4 months after termination of feedback training. Both prior to and following the 9 weeks of biofeedback training, patients were given the Category Test (a subtest of the Halstead-Reitan Neuropsychological Test Battery). Feedback training resulted in significant reductions in blood pressure both within and outside of the laboratory. The reduction in non-laboratory pressure readings persisted for up to 4 months after feedback training was terminated. A significant positive correlation was found between systolic pressure and number of errors on the Category Test given prior to biofeedback training, and between magnitude of decrease in systolic pressure recorded during biofeedback training and improvement in Category Test performance measured subsequent to training. After completion of the study, patients were rated (on the basis of structured interview data obtained following weekly feedback sessions) as to overall level of stress (i.e., general stressfulness of life style, accidents, illnesses, emotional problems, etc.). Patients rated high in overall stress had significantly higher blood pressure readings during the control period. However, magnitude of decrease in blood pressure recorded during feedback training was essentially the same regardless of rated stress level.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1469-8986.1977.tb03375.x
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  • 2
    Electronic Resource
    Electronic Resource
    AN ACCURATE ONE CHANNEL BASAL LEVEL/RESPONSE SIGNAL SEPARATOR FOR SKIN RESISTANCE, INCORPORATING PULSE CODING OF THE BASAL LEVEL (1969)
    Oxford, UK : Blackwell Publishing Ltd
    Psychophysiology 6 (1969), S. 0 
    Details
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: We have developed a method for measuring SR which combines the accuracy of DC measurement of basal SR level with the convenience gained from the AC coupling of SR responses for purposes of separating the total signal into basal SR level and SR responses. Our circuitry accomplishes (1) amplification of total DC signal, (2) post-amplification signal separation and display of SR responses and, on the same display channel, (3) pulse coding of basal SR.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1469-8986.1969.tb02902.x
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  • 3
    Electronic Resource
    Electronic Resource
    Relationship Between Essential Hypertension and Cognitive Functioning: Effects of Biofeedback (1975)
    Oxford, UK : Blackwell Publishing Ltd
    Psychophysiology 12 (1975), S. 0 
    Details
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: Seven malt essential hypertensives underwent 9 weekly 2-hr biofeedback training sessions in an attempt to produce decreases in blood pressure. Feedback, contingent Upon heart bent by heart beat decreases in systolic pressure, was provided by an automated blood pressure monitoring system. The subjects were administered the Category Test (a subtest of the HaLstead-Reitan Neuropsychological test Battery) both before and after biofeedback training. As controls, 4 male hypertensives underwent 3 weekly sessions in which blood pressure was monitored without feedback being provided. Prior to training, a significant positive correlation was otained between systolic blood pressure and number of errors made on the Category Test, Biofeedback training produced significant decreases in systolic pressure within sessions and in diastolic pressure between sessions, in the control subjects, no significant changes in pressure were observed. For both systolic and diastolic pressures, significant correlations w-ere obtained between magnitude of decrease during biofeedback training and improvement in Category Test scores subsequent to training.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1469-8986.1975.tb00049.x
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  • 4
    Electronic Resource
    Electronic Resource
    Ethanol and Methanol Metabolites in Alcohol Withdrawal (1973)
    [s.l.] : Nature Publishing Group
    Nature 244 (1973), S. 234-235 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] All participating subjects received chlordiazepoxide, flura-zepam and a high potency vitamin B complex and C in a fixed schedule5,6. About one-half of the subjects had initial blood levels of ethanol of less than 100 mg/100 ml, while those of the remainder were well above 100 mg/100 ml. We ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/244234a0
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  • 5
    Electronic Resource
    Electronic Resource
    Pharmacological Investigation of a New Psychoactive Agent (1966)
    [s.l.] : Nature Publishing Group
    Nature 209 (1966), S. 1249-1250 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Neither the chemical structure nor the reported pharmacological action of this compound was typical of the iminodibenzyl- or phenothiazine-type psycho therapeutic agents. The results of the clinical investigation are reported elsewhere1. This compound was investigated because it significantly ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/2091249a0
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  • 6
    Electronic Resource
    Electronic Resource
    Controlled release of diltiazem hydrochloride (1995)
    New York, NY [u.a.] : Wiley-Blackwell
    Polymer International 38 (1995), S. 311-317 
    Details
    ISSN: 0959-8103
    Keywords: drug-delivery systems ; poly(2-hydroxyethyl methacrylate) ; poly(ethylene glycol) ; diltiazem hydrochloride ; reservoir-matrix systems ; zero-order release kinetics ; membrane barriers ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A new type of complex reservoir-matrix system for the controlled delivery of diltiazen hydrochloride was developed. This capsule-type device was designed for oral administration to humans and/or animals. It contained (i) an appropriate amount of the drug in a compartment; (ii) a swelling-controlled membrane which was prepared by mixing polymeric materials with another appropriate amount of the drug; and (iii) a water-soluble gelatin capsule as container. The swelling-controlled membranes were prepared from poly(2-hydroxyethyl methacrylate) hydrogels. The effect of pH on the swelling of the hydrogels was studied. In-vitro dissolution testing was carried out to evaluate the release of the drug using a continuous-flow method. Zero-order release kinetics was obtained over a period of 12 h.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pi.1995.210380401
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