Note: Intro -- Contents -- Preface -- Chapter 1 -- Pathogenic Intestinal Entamoeba Species in Humans: Epidemiology, Pathogenesis and Management -- Abstract -- Introduction -- Entamoeba Species Infecting Humans -- Epidemiology -- Developed World -- Developing Countries -- Pathogenicity -- Luminal Amoebiasis -- Amebic Colitis -- Extra-Intestinal Amoebiasis -- Diagnostic Approaches -- Microscopy -- Culture -- Isoenzyme Analysis -- Antigen Detection Test -- Antibody Detection Test -- Conventional Polymerase Chain Reaction (PCR) -- Real Time PCR -- Loop Mediated Isothermal Amplification Assay (LAMP) -- Microarray -- Treatment -- Prevention -- Future Challenges -- References -- Chapter 2 -- Pathogenic and Non-Pathogenic Species of Entamoeba -- Abstract -- 1. Introduction and Classification -- 2. Various Species of Genus Entamoeba -- 2.1. Entamoeba histolytica (E. histolytica) -- 2.2. Entamoeba gingivalis (E. gingivalis) -- 2.3. Entamoeba invadens (E. invadens) -- 2.4. Entamoeba dispar (E. dispar) -- 2.5. Entamoeba moshkovskii (E. moshkovskii) -- 2.6. Entamoeba polecki (E. polecki) -- 2.7. Entamoeba hartmani (E. hartmani) -- 2.8. Entamoeba coli (E. coli) -- 2.9. Entamoeba bangladeshi (E. bangladeshi) -- 2.10. Entamoeba nuttali (E. nuttali) -- 2.11. Entamoeba antilocapra (E. antilocapra) -- 2.12. Entamoeba bovis (E. bovis) -- 2.13. Entamoeba apis (E. apis) -- 2.14. Entamoeba struthionis (E. struthionis) -- 2.15. Entamoeba gallinarum (E. gallinarum) -- 2.16. Entamoeba anatis (E. anatis) -- 2.17. Entamoeba muris (E. muris) -- 2.18. Entamoeba suis (E. suis) -- 2.19. Entamoeba cobaye (E. cobaye) -- 2.20. Entamoeba chattoni (E. chattoni) -- 2.21. Entamoeba citelli (E. citelli) -- 2.22. Entamoeba criceti (E. criceti) -- 2.23. Entamoeba cuniculi (E. cuniculi) -- 2.24. Entamoeba chiropteris (E. chiropteris) -- 2.25. Entamoeba dipodomysi (E. dipodomysi). , 2.26. Entamoeba funambulae (E. funambulae) -- 2.27. Entamoeba flaviviridis (E. flaviviridis) -- 2.28. Entamoeba polypodia (E. polypodia) -- 2.29. Entamoeba marmotae (E. marmotae) -- 2.30. Entamoeba wenyoni (E. wenyoni) -- 2.31. Entamoeba ranarum (E. ranarum) -- 2.32. Entamoeba aulastomi (E. aulastomi) -- 2.33. Entamoeba lagopodis (E. lagopodis) -- 2.34. Entamoeba ecuadoriensis (E. ecuadoriensis) -- 2.35. Entamoeba marina (E. marina) -- Conclusion -- References -- Chapter 3 -- Infection by Entamoeba histolytica and Immunity against This Enteric Parasite -- Abstract -- Introduction -- Entamoeba histolytica Life Cycle -- Clinical Manifestations -- Luminal Amoebiasis -- Disseminated Amoebic Disease -- Laboratory Diagnosis -- Pathogenic Mechanisms of Entamoeba histolytica -- Microbiome and Dysbiosis -- Amoeba Adhesion to Intestinal Epithelium -- Epithelial Cell Lysis -- Phagocytosis and Trogocytosis -- Opening of Tight Junctions and Tissue Invasion -- Immune Response to Entamoeba histolytica -- Innate Immune Mechanisms -- Humoral Immune Response -- Cellular Immune Response -- Conclusion -- Acknowledgments -- Conflict of Interest -- References -- Chapter 4 -- Programmed Cell Death (PCD) in Entamoeba histolytica -- Abstract -- Introduction -- PCD -- PCD in Protozoans -- PCD in Entamoeba histolytica -- Conclusion -- References -- Chapter 5 -- Structural and Functional Studies of Serine Biosynthetic Pathway Enzymes in E. histolytica -- Abstract -- Introduction -- D-Phosphoglycerate Dehydrogenase from Entamoeba histolytica (EhPGDH) -- Structural Details of EhPGDH -- EhPGDH Is a Dimeric Enzyme -- Ligand Binding Induces Domain Movement That Leads to Cleft Closure -- Phosphoserine Aminotransferase from Entamoeba histolytica (EhPSAT) -- Structure of EhPSAT -- The Functional Unit of EhPSAT Is a Dimer -- The Active Site. , EhPGDH and EhPSAT Display Novel Interaction Mode -- Phosphoserine Phosphatase from Entamoeba histolytica (EhPSP) -- EhPSP: Structural Insights -- The Conserved Active Site Pocket -- Phosphoserine Phosphatase Safeguards Entamoeba histolytica during Oxidative Stress -- Regulation of Serine Biosynthetic Pathway in Entamoeba histolytica -- Conclusion -- References -- Index -- Blank Page -- Blank Page.