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  • 1
    Publication Date: 2023-12-12
    Description: 〈title xmlns:mml="http://www.w3.org/1998/Math/MathML"〉Abstract〈/title〉〈p xmlns:mml="http://www.w3.org/1998/Math/MathML" xml:lang="en"〉The Canadian Arctic Southern Beaufort Sea is characterized by prominent relict submarine permafrost and gas hydrate occurrences formed by subaerial exposure during extensive glaciations in Pliocene and Pleistocene. Submarine permafrost is still responding to the thermal change as a consequence of the marine transgression that followed the last glaciation. Submarine permafrost is still underexplored and is currently the focus of several research projects as its degradation releases greenhouse gases that contribute to climate change. In this study, seismic reflection indicators are used to investigate the presence of submarine permafrost and gas hydrates on the outer continental shelf where the base of permafrost is expected to cross‐cut geological layers. To address the challenges of marine seismic data collected in shallow water environments, we utilize a representative synthetic model to assess the data processing and the detection of submarine permafrost and gas hydrate by seismic data. The synthetic model allows us to minimize the misinterpretation of acquisition and processing artifacts. In the field data, we identify features along with characteristics arising from the top and base of submarine permafrost and the base of the gas hydrate stability zone. This work shows the distribution of the present submarine permafrost along the southern Canadian Beaufort Sea region and confirms its extension to the outer continental shelf. It supports the general shape suggested by previous works and previously published numerical models.〈/p〉
    Description: Plain Language Summary: Submarine permafrost, ground beneath the seafloor that perennially remains below 0°C, is present on the continental shelf of the Canadian Beaufort Sea. During the Late Pleistocene (∼1 Million years ago), the continental shelf was subaerially exposed to the cold Arctic air causing the formation of ice in the ground. This period was followed by a sea level rise that flooded the continental shelf with warmer waters, resulting in an intensive change of the thermal regime. The relict permafrost still reacts to this thermal change and is continuously thawing. Associated with the presence of relict permafrost, extensive gas hydrates exist to >1,000 m below the seafloor. Climate warming threatens both the stability of permafrost and associated gas hydrates. Their thawing and decomposition can cause a release of greenhouse gases which in turn amplifies climate warming. This study uses marine seismic reflection data to identify permafrost and gas hydrate in the southern Canadian Beaufort Sea. We find indicators of the top and base of permafrost and the base of the gas hydrate stability zone in the outer continental shelf area. Our work shows that the permafrost and gas hydrates still extend to the outer continental shelf and thereby supports previously published numerical models.〈/p〉
    Description: Key Points: 〈list list-type="bullet"〉 〈list-item〉 〈p xml:lang="en"〉Seismic reflection data reveal occurrences and extent of submarine permafrost and associated gas hydrates at the Canadian Beaufort Shelf〈/p〉〈/list-item〉 〈list-item〉 〈p xml:lang="en"〉Synthetic modeling of permafrost and gas hydrate is required to assess seismic processing minimizing the potential for misinterpretation〈/p〉〈/list-item〉 〈list-item〉 〈p xml:lang="en"〉Indicators of top and base of permafrost and the base of gas hydrate stability support previously published numerical models〈/p〉〈/list-item〉 〈/list〉 〈/p〉
    Description: Deutsche Forschungsgemeinschaft http://dx.doi.org/10.13039/501100001659
    Description: Korean Ministry of Oceans and Fisheries
    Description: Environmental Geoscience Program of the Geological Survey of Canada
    Description: https://dx.doi.org/doi:10.22663/KOPRI-KPDC-00001958.3
    Keywords: ddc:551 ; submarine permafrost ; gas hydrate ; marine seismic ; Canadian Beaufort Sea ; seismic reflection
    Language: English
    Type: doc-type:article
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  • 2
    Publication Date: 2019-07-17
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , peerRev
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  • 3
    Publication Date: 2014-07-16
    Description: Vascular remodeling and smooth muscle cell proliferation are hallmark pathogenic features of pulmonary artery hypertension. MicroRNAs, endogenously expressed small noncoding RNAs, regulate gene expression at the posttranscriptional level. It has previously been shown that miR-17 overexpression in cultured human pulmonary artery smooth muscle cell (hPASMC) resulted in increased viable cell number. Previously, we have found that arginase II promotes hypoxia-induced proliferation in hPASMC. Therefore, we hypothesized that miR-17 would be upregulated by hypoxia in hPASMC and would result in greater arginase II expression. We found that levels of miR-17-5p and arginase II were significantly greater in cultured hPASMC exposed to 1% O 2 for 48 h than in hPASMC exposed to 21% O 2 for 48 h. Furthermore, inhibiting miR-17-5p expression decreased hypoxia-induced arginase II protein levels in hPASMC. Conversely, overexpressing miR-17-5p resulted in greater arginase II protein levels. Somewhat surprisingly, arginase II inhibition was associated with lower miR-17-5p expression in both normoxic and hypoxic hPASMC, whereas overexpressing arginase II resulted in greater miR-17-5p expression in hPASMC. These findings suggest that hypoxia-induced arginase II expression is not only regulated by miR-17-5p but also that there is a feedback loop between arginase II and miR-17-5p in hPASMC. We also found that the arginase II-mediated regulation of miR-17-5p was independent of either p53 or c- myc . We also found that l -arginine, the substrate for arginase II, and l -ornithine, the amino acid product of arginase II, were not involved in the regulation of miR-17-5p expression.
    Print ISSN: 1040-0605
    Electronic ISSN: 1522-1504
    Topics: Medicine
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  • 4
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: We report here the positional cloning and molecular characterization of the unc-24 gene of Caenorhabditis elegans. This gene is required for normal locomotion and interacts with genes that affect the worm's response to volatile anesthetics. The predicted gene product contains a domain similar to part of two ion channel regulators (the erythrocyte integral membrane protein stomatin and the C. elegans neuronal protein MEC-2) juxtaposed to a domain similar to nonspecific lipid transfer protein (nsLTP; also called sterol carrier protein 2). Sequence analysis suggests that the nsLTP-like domain of UNC-24 provides lipid carrier function and is tethered to the plasma membrane by the stomatin-like domain, which may be regulatory. We postulate that UNC-24 may be involved in lipid transfer between closely apposed membranes.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 80 (1996), S. 464-469 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Electroluminescence spectroscopy of short gate high-electron-mobility transistors (HEMTs) on InP substrates is performed at cryogenic temperatures. Electroluminescence is a reliable tool to investigate impact ionization as compared to studies based on gate current which depend on the weakness of the intrinsic gate current intensity. In on-state biased devices, a low energy (0.7–0.9 eV) recombination band is observed which is related to radiative recombination of carriers created by impact ionization in the low band gap InGaAs channel. The evolution of the luminescence intensity versus bias applied to the device shows that the electroluminescence intensity and impact ionization depend on two competing parameters: the electric field in the gate–drain access area and the drain current intensity. We show that the so-called "kink'' effect, which is a noticeable increase of the output conductance and which is observed at relatively moderate drain bias (600–750 mV) in our devices, is not correlated with impact ionization. The electroluminescence of the device in the off state is also investigated. This study allows the direct observation of impact ionization in the off-biased channel of InP-based HEMTs. In this low current regime, the electroluminescence intensity follows the electric field, i.e., the drain–gate voltage until breakdown of the device occurs. The voltage breakdown of the device in the off state is discussed in terms of impact ionization in the InGaAs channel due to hot carriers originating from the gate leakage current. Finally, a method for reducing or avoiding impact ionization in these devices, i.e., for increasing the device reliability, is discussed. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 77 (1995), S. 2184-2189 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Electroluminescence of pseudomorphic InGaAs high-electron-mobility transistors (HEMTs) on GaAs and of standard AlGaAs/GaAs HEMTs with ultrashort gate lengths is investigated at room and cryogenic temperatures. The spectral distribution of the emitted radiation is analyzed in the 0.7–1.6 eV energy range. In the case of pseudomorphic transistors, three different recombination lines originating from distinct layers are observed: a broad luminescence band around 0.8–0.9 eV; a doublet arising from confined subbands in the InGaAs layer; and a single peak coming from the GaAs substrate. The energy position and the temperature dependence of these different lines under various biases give valuable information on the physical mechanisms which occur under high-electric-field nonstationary transport: lattice self-heating (≈150 K at high-bias conditions), origin of the impact ionization in the channel of the quantum-well layer, and perpendicular transfer of hot holes which recombine with the barrier DX centers thus leading to the broad luminescence band. These characteristics are supported by comparison with analog standard HEMTs and with electrical measurements. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 68 (1997), S. 1575-1581 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A dynamic pulsed plasma reactor (DPPR) capable of chemical vapor deposition of advanced materials on substrates located in a supersonic expansion nozzle is described. The DPPR combines plasma, shock tube, and supersonic expansion nozzle techniques in obtaining vapor phase quenching rates of 107–108 K/s for nanometric particle size formation. Deposition of Ti(s) and TiN(s) from Ar–TiCl4, Ar–H2–TiCl4, and N2–H2–TiCl4 reactants were experimentally investigated with deposition products characterized by scanning electron microscopy, atomic force microscopy, and energy dispersive x-ray analytical techniques. Theoretical gas dynamics describing wave motion and propagation of reactants in the DPPR are presented and resulted in identifying deposition mechanisms of homogeneous and heterogeneous nucleation for Ti(s) and TiN(s) on Pyrex substrates, respectively. This article describes reactor design, operating characteristics, and theoretical wave dynamics in the experimental system. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 67 (1996), S. 3675-3678 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A microwave compatible electromagnetic valve capable of discharging saturated vapors in vacuum for shock wave formation and subsequent pulsed plasma deposition is presented. The valve discharges vapors of 1–5 atm and 75 °C with open duration times of 36–178 μs into vacuum. A theoretical model describing rarefaction wave motion coupled with a valve dynamic model was used to determine critical open duration time required for driving a shock wave in the experimental system. Valve design, operating characteristics, and rarefaction wave dynamics for H2, He, Ar, and CO2 internal to the valve are described. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 92 (2002), S. 1065-1068 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We report a method to fabricate carbon nanotubes (CNT)/conducting polymer composite films for the application of CNTs to field emission displays. The composite was prepared by a combination of electrochemical polymerization of pyrrole and electrophoretic deposition of CNTs. We obtained a uniform CNT/conducting polypyrrole polymer composite film. The CNTs were mainly coated on protrusions of the polypyrrole film and emitted electrons without rubbing and stretching. We realized a triode-type field emission array (FEA) using the CNT/polypyrrol composite. This FEA showed that the emission current was modulated by gate voltage of 30 V. The film morphology and emission characteristics of the CNT/conducting polymer composite were studied using optical microscopy, scanning electron microscopy, and an emission test in vacuum. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 70 (1991), S. 4113-4120 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The propagation of the lowest-order symmetric (S0) and antisymmetric (A0) Lamb wave modes in a piezoelectric plate is investigated both theoretically as well as experimentally. The characteristics of the modes and their relation to the surface acoustic wave is modified by electrical boundary conditions on the plate surfaces. It is found that when both surfaces are either metallized or unmetallized, the surface acoustic wave is obtained by a linear superposition of the A0 and S0 modes. On the other hand, if only one surface is metallized, then the surface acoustic wave is equivalent to just one of modes (either the A0 or S0 mode, depending on which surface is metallized). The beating phenomenon, whereby wave energy launched on one surface transfers periodically back and forth between opposite plate surfaces, is present when both surfaces are either metallized or unmetallized, but is absent if only one surface is metallized. Experimental measurements performed on Lamb wave devices fabricated on Y-cut, Z-propagating lithium niobate plates are found to be in good agreement with theoretical calculations.
    Type of Medium: Electronic Resource
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