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  • 1
    Electronic Resource
    Electronic Resource
    Fertilization in Trypsin–Treated Oocytes (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 541 (1988), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1988.tb22298.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A self-programmable in vitro fertilization/gamete intrafallopian transfer patient database management system for MacIntosh Computers (1993)
    Springer
    Journal of assisted reproduction and genetics 10 (1993), S. 58-66 
    Details
    ISSN: 1573-7330
    Keywords: database ; in vitro fertilization ; gamete intrafallopian transfer ; computers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Results A database management system was successfully constructed on an Apple MacIntosh computer which met the above criteria. The key elements of this database were its user-friendly features (MacIntosh-based system), adaptability (user was constantly able to update and revise the program as informational needs changed), and ability to perform complex searches and data analyses imposed by the individual operators.
    Abstract: Conclusions The software and hardware described in this report were found to be highly effective in meeting the ever-changing administrative and clinical needs of our IVF/GIFT program.
    Notes: Purpose Our purpose was to develop a data processing system for a large in Vitro Fertilization/Gamete Intrafallopian Transfer (IVF/GIFT) practice which would (1) require minimal data entry time, (2) be easy to operate, (3) be simple to construct (no knowledge of procedural language or programming necessary), and (4) quickly collate and reduce data.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01204442
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  • 3
    Electronic Resource
    Electronic Resource
    Effects of Endometriomas on Ooccyte Quality, Embryo Quality, and Pregnancy Rates in In Vitro Fertilization Cycles: A Prospective, Case-Controlled Study (1998)
    Springer
    Journal of assisted reproduction and genetics 15 (1998), S. 193-197 
    Details
    ISSN: 1573-7330
    Keywords: embryos ; endometriosis ; in vitro fertilization ; spontaneous abortion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Purpose: The effect of endometriomas on oocyte quality, embryo quality, and pregnancy rates in in vitro fertilization (IVF) cycles was evaluated. Methods: Forty-five women had “chocolate” cysts aspirated at the time of oocyte retrieval, and cyst fluid CA 125 levels were measured to ascertain presence of “true” endometriomas. Fifty-seven women without any complex cysts at the time of oocyte retrieval served as controls. IVF cycle outcome parameters were compared between the two groups. Results: Women with endometriomas experienced a significantly higher rate of early pregnancy loss compared to controls (47 vs 14%). There was also a trend toward fewer oocytes retrieved and fewer embryos reaching at least the four-cell stage 48 hr after retrieval in patients with true endometriomas vs controls. Conclusions: The presence of endometriomas at the time of oocyte retrieval is associated with increased rates of early pregnancy losses. The number of oocytes retrieved and the embryo quality may also be affected adversely in the presence of endometriomas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1023048318719
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  • 4
    Electronic Resource
    Electronic Resource
    The effect of elevated serum progesterone during ovulation induction in in vitro fertilization-embryo transfer (1996)
    Springer
    Journal of assisted reproduction and genetics 13 (1996), S. 617-624 
    Details
    ISSN: 1573-7330
    Keywords: in vitro fertilization ; progesterone ; embryo transfer ; fertilization ; follicles ; estradiol ; clinical pregnancy ; assisted reproductive technology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: Our purpose was to determine whether elevated progesterone (P) during ovulation induction in IVF-ET cycles is a poor prognostic factor for achieving pregnancy. Design: We retrospectively reviewed 672 consecutive IVF-ET cycles in which ovulation was performed using luteal LA downregulation and hMG. Setting: The ART program at the Brigham & Women's Hospital, a tertiary care institution, was the study setting. Main Outcome Measures: Patients were divided into groups by serum P levels at baseline, on stimulation day 5, on the day of hCG injection, and, on the day after hCG injection and the following parameters were compared: duration of luteal LA treatment, number of ampoules of hMG used, estradiol (E2) levels, number of follicles ≥12 mm, number of follicles ≥15 mm, number of oocytes, number of normal embryos, number of polyspermic embryos, fertilization rate, implantation rate, and clinical and ongoing/live birth pregnancy rates. Results: Based on serum P level, patients were divided into three groups: Group I, ≤0.31 ng/ml (conversion factor to SIU, 3.180); Group II, and 〉0.3 and 〈1.0 ng/ml and Group III, ≥1.0 ng/ml. Measureable P at baseline was associated with a higher cancellation rate, but no difference in other cycle outcome parameters. Progesterone 〉0.31 ng/ml on stimulation day 5 was associated with a higher fertilization rate in Groups II and III, but there was no difference in the clinical pregnancy or ongoing/live birth rates among the three groups. Based on P on the day of hCG administration, Groups II and III had significantly more oocytes and higher fertilization rates than did Group I, however, clinical pregnancy and ongoing/live birth rates were not significantly different. On the day after hCG, there was a trend toward a higher clinical pregnancy rate in Group III, which had younger patients, better follicular recruitment, and more embryos than Groups I or II, but these differences did not reach statistical significance. Conclusions: Serum P 〉0.31 ng/ml during ovulation induction reflects good follicular recruitment, and is not a predictor of IVF outcome.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02069639
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  • 5
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    Rope trauma, sedation, disentanglement, and monitoring-tag associated lesions in a terminally entangled North Atlantic right whale (Eubalaena glacialis) (2013)
    John Wiley & Sons
    Details
    Publication Date: 2022-05-25
    Description: Author Posting. © Society for Marine Mammalogy, 2012. Re-use of this article is permitted in accordance with the Terms and Conditions set out at http://wileyonlinelibrary.com/onlineopen#OnlineOpen_Terms. The definitive version was published in Marine Mammal Science 29 (2013): E98–E113, doi:10.1111/j.1748-7692.2012.00591.x.
    Description: A chronically entangled North Atlantic right whale, with consequent emaciation was sedated, disentangled to the extent possible, administered antibiotics, and satellite tag tracked for six subsequent days. It was found dead 11 d after the tag ceased transmission. Chronic constrictive deep rope lacerations and emaciation were found to be the proximate cause of death, which may have ultimately involved shark predation. A broadhead cutter and a spring-loaded knife used for disentanglement were found to induce moderate wounds to the skin and blubber. The telemetry tag, with two barbed shafts partially penetrating the blubber was shed, leaving barbs embedded with localized histological reaction. One of four darts administered shed the barrel, but the needle was found postmortem in the whale with an 80º bend at the blubber-muscle interface. This bend occurred due to epaxial muscle movement relative to the overlying blubber, with resultant necrosis and cavitation of underlying muscle. This suggests that rigid, implanted devices that span the cetacean blubber muscle interface, where the muscle moves relative to the blubber, could have secondary health impacts. Thus we encourage efforts to develop new tag telemetry systems that do not penetrate the subdermal sheath, but still remain attached for many months.
    Description: Funding from NOAA Cooperative Agreement NA09OAR4320129, PO EA133F09SE4792, M. S. Worthington Foundation, North Pond Foundation, Sloan and Hardwick Simmons, and Woods Hole Oceanographic Institution Marine Mammal Center.
    Keywords: Right whale ; Eubalaena glacialis ; Entanglement ; Trauma ; Shark predation ; Tag
    Repository Name: Woods Hole Open Access Server
    Type: Article
    Format: application/pdf
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  • 6
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    Behavioral impacts of disentanglement of a right whale under sedation and the energetic cost of entanglement (2014)
    Details
    Publication Date: 2022-05-25
    Description: Author Posting. © The Author(s), 2013. This is the author's version of the work. It is posted here by permission of Society for Marine Mammalogy for personal use, not for redistribution. The definitive version was published in Marine Mammal Science 30 (2014): 282–307, doi:10.1111/mms.12042.
    Description: Protracted entanglement in fishing gear often leads to emaciation through reduced mobility and foraging ability, and energy budget depletion from the added drag of towing gear for months or years. We examined changes in kinematics of a tagged entangled North Atlantic right whale (Eg 3911), before, during and after disentanglement on 15 Jan 2011. To calculate the additional drag forces and energetic demand associated with various gear configurations, we towed three sets of gear attached to a load-cell tensiometer at multiple speeds. Tag analyses revealed significant increases in dive depth and duration; ascent, descent and fluke stroke rates; and decreases in root mean square fluke amplitude (a proxy for thrust) following disentanglement. Conservative drag coefficients while entangled in all gear configurations (mean ± SD Cd,e,go = 3.4x10-3 ± 0.0003, Cd,e,gb = 3.7x10-3 ± 0.0003, Cd,e,sl = 3.8x10-3 ± 0.0004) were significantly greater than in the nonentangled case (Cd,n = 3.2x10-3±0.0003; P = 0.0156, 0.0312, 0.0078 respectively). Increases in total power input (including standard metabolism) over the nonentangled condition ranged 1.6%-120.9% for all gear configurations tested; locomotory power requirements increased 60.0%-164.6%. These results highlight significant alteration to swimming patterns, and the magnitude of energy depletion in a chronically entangled whale.
    Description: Funding sources include NOAA Cooperative Agreement NA09OAR4320129, PO EA133F09SE4792, the M.S. Worthington Foundation, the North Pond Foundation, Sloan and Hardwick Simmons.
    Description: 2014-05-21
    Keywords: Disentanglement ; Dtag ; Drag ; Energetics ; Entanglement ; Sedation ; Right whale ; Eubalaena glacialis
    Repository Name: Woods Hole Open Access Server
    Type: Preprint
    Format: application/pdf
    Format: image/jpeg
    Format: application/postscript
    Format: image/tiff
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