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  • 1
    ISSN: 1436-2813
    Keywords: Turner's syndrome ; aortic dissection ; cystic medionecrosis ; horseshoe-shaped patch plasty
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report herein the successful surgical management of a 42-year-old patient with Turner's syndrome (TS) complicated by Stanford type B aortic dissection. The patient had a single entry in the proximal descending aorta with dissection extending from the entry point to the abdominal aorto-left iliac bifurcation. A patch plasty using felt reinforcement was performed through a left 4th intercostal space thoracotomy. Her postoperative course was uneventful and she has been well during the 3 years since her operation. There have been only nine reports of patients with TS complicated by aortic dissection for whom operations were performed; however, the details of surgical treatment have not been well documented. This paper reports the course of aortic dissection and the surgical methods employed in the treatment of our patient.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-2568
    Keywords: zinc ; zincl-carnosine ; gastric mucosa ; prostaglandin ; indomethacin ; cytoprotection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of zincl-carnosine on ethanol-induced damage and the correlation of these effects with endogenous prostaglandin E2 were evaluated in rat gastric mucosain vivo andin vivo. When given either intragastrically or intraperitoneally, zincl-carnosine (10 or 30 mg/kg) prevented gross visible damage to gastric mucosa caused by ethanol without affecting the mucosal prostaglandin E2 level. This protective effect of zincl-carnosine was not inhibited by indomethacin. Histological assessment showed that zincl-carnosine inhibited deep mucosal necrosis, as did 16,16-dimethyl-prostaglandin E2. Zincl-carnosine (10−6 or 10−5 M) inhibited the damage caused by ethanol to gastric cells isolated from rat gastric mucosain vivo; this effect was not inhibited by indomethacin. The results suggested that zincl-carnosine protects the gastric mucosa and enhances cellular resistance to ethanol without the mediation of endogenous prostaglandins.
    Type of Medium: Electronic Resource
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