Note: Front Cover -- The Primate Nervous System, Part III -- Copyright Page -- Contents -- Chapter I. The Human Basal Forebrain. Part I. An Overview -- 1. Introduction -- 2. Surface topography -- 3. Overview of basal forebrain structures -- 4. Coronal sections through the basal forebrain -- 5 . Acknowledgements -- 6. References -- Chapter II. The Human Basal Forebrain. Part II -- 1. Introduction -- 2. Ventral striatopallidal system -- 3. Extended amygdala -- 4. Olfactory system -- 5. Superficial amygdala and the laterobasal complex -- 6. Concluding remarks -- 7. Appendix: comparison of nomenclature for the human amygdala -- 8. Acknowledgements -- 9. Abbreviations -- 10. References -- Chapter III. Chemical Architecture of the Basal Ganglia -- 1. Introduction -- 2. Systems approach to the basal ganglia -- 3. Functional concepts about the basal ganglia -- 4. Chemically specified subsystems : receptor systems in the basal ganglia -- 5. Future directions -- 6. Acknowledgement -- 7. References -- Chapter IV. Chemical Neuroanatomy of the Hippocampal Formation and the Perirhinal and Parahippocampal Cortices -- 1. Introduction -- 2. Overview of the components of the medial temporal lobe -- 3. Cytoarchitectonic organization of the hippocampal formation -- 4. Regional and cytoarchitectonic features of the perirhinal and parahippocampal cortices -- 5. An overview of the connectivity of the hippocampal formation -- 6. Dentate gyrus -- 7. Hippocampus -- 8. Subiculum -- 9. Presubiculum and parasubiculum -- 10. Entorhinal cortex -- 11. Perirhinal cortex -- 12. Parahippocampal cortex -- 13. Concluding remarks -- 14. Abbreviations -- 15. References -- Chapter V. The Primate Mesocortical Dopamine System -- 1. Introduction -- 2. Primate specialization in the brainstem origin and organization of the mesocortical dopamine system. , 3. Qualitative organization of the dopamine innervation of cerebral cortex -- 4. Quantitative analysis of dopamine contacts on pyramidal and non- pyramidal neurons -- 5. Electronmicroscopic evidence of dopamine synaptic triads and D1 receptor localization in spines -- 6. Dopamine innervation of the microvasculature -- 7. Dopamine D1 and D2 family of receptors in the cerebral cortex -- 8. Role of dopamine receptors in cortical function -- 9. Regulation of cortical dopamine receptors as targets of antipsychotic drugs -- 10. Summary and future directions -- 11. References -- Subject Index.

Note: Front Cover -- Peptide Receptors -- Copyright Page -- Contents -- List of Contributors -- Preface -- CHAPTER I. OPIOID RECEPTORS -- 1. Introduction -- 2. Opioids -- 3. Opioid receptor subtypes -- 4. Distribution of opioid receptors in the rat brain -- 5. Conclusions -- 6. Abbreviations -- 7. Acknowledgements -- 8. References -- CHAPTER II. THE MELANIN-CONCENTRATING HORMONE -- 1. A survey of the melanin-concentrating system: seminal background studies and pharmaceutical interest -- 2. The pro-MCH gene, regulation of expression and precursor processing -- 3. Features of the MCH system in the rat CNS -- 4. Central effects of MCH -- 5. The MCH receptors -- 6. Conclusion -- 7. Abbreviations -- 8. Acknowledgements -- 9. References -- CHAPTER III. NEUROANATOMICAL STUDIES OF THE OPIOID RECEPTOR-LIKE-1 RECEPTOR AND ITS ENDOGENOUS NEUROPEPTIDE ORPHANIN FQ (NOCICEPTIN) -- 1. Introduction -- 2. General characteristics -- 3. Biological effects of OFQ binding at the ORL1 receptor -- 4. Anatomical studies of the orphanin peptide-receptor system -- 5. In situ hybridization and immunohistochemistry studies -- 6. Anatomical studies using 125I-[14Tyr]OFQ binding and agonist stimulated [35S]GTPγS receptor autoradiography -- 7. Ontogeny studies -- 8. Physiological implications of OFQ and the ORL1 receptor -- 9. Concluding remarks -- 10. Abbreviations -- 11. Acknowledgements -- 12. References -- CHAPTER IV. LOCALIZATION OF GALANIN RECEPTOR SUBTYPES IN THE RAT CNS -- 1. Introduction -- 2. Galanin -- 3. Galanin receptor subtypes -- 4. Localization of galanin receptors in the rat CNS -- 5. Expression of GALRs by glial cells -- 6. Localization of galanin receptors in the circumventricular organs of the rat -- 7. Localization of galanin receptors in dorsal root ganglia of the rat -- 8. Concluding remarks -- 9. Abbreviations -- 10. Acknowledgements -- 11. References. , CHAPTER V. OREXIN RECEPTORS -- 1. Introduction -- 2. Biology of orexins -- 3. Orexin receptors -- 4. Distribution of orexin receptor mRNA and protein in mammalian central nervous system -- 5. Comparison of OX1R and OX2R distribution -- 6. Comparison of OX1R mRNA and protein distribution -- 7. Comparison between localization of orexin receptor and sites of c-Fos activation upon central administration of orexins in rat -- 8. How many orexin receptors? -- 9. Physiological and pathophysiological implications of orexin receptors -- 10. Conclusion -- 11. Abbreviations -- 12. Acknowledgements -- 13. References -- CHAPTER VI. NEUROTENSIN RECEPTORS IN THE CENTRAL NERVOUS SYSTEM -- 1. Introduction -- 2. Discovery of NT -- 3. Distribution of NT in the CNS -- 4. Central effects of NT -- 5. NT receptors in mammalian CNS -- 6. Summary and conclusions -- 7. Abbreviations -- 8. Acknowledgements -- 9. References -- Subject Index.

Note: Front Cover -- The Primate Nervous System -- Copyright Page -- Contents -- Chapter I. A Digital Rosetta Stone for Primate Brain Terminology -- 1. Introduction -- 2. Status of digital atlas development -- 3. Neuronames: a semantic network of the classical neuroanatomical nomenclature -- 4. The template atlas: image representation of the classical neuroanatomical nomenclature -- 5. What a standard nomenclature and template atlas can do for you -- 6. Acknowledgements -- 7. References -- Chapter II. Neurobiology and Neuropathology of the Human Hypothalamus -- 1. Introduction -- 2. Nucleus Basalis of Meynert and diagonal band of Broca -- 3. Islands of Calleja (insulae terminalis) -- 4. Suprachiasmatic nucleus -- 5. Sexually dimorphic nucleus (intermediate nucleus, INAH-1) -- 6. Other hypothalamic sexually dimorphic structures (INAH-2,3, BST, SCN, anterior commissure) -- 7. Bed nucleus of the stria terminalis (BST) -- 8. Supraoptic and paraventricular nucleus (SON, PVN) -- 9, The ventromedial nucleus (Nucleus of Cajal) -- 10. Dorsomedial nucleus -- 11. Infundibular nucleus (arcuate nucleus) and subventricular nucleus -- 12. Lateral tuberal nucleus -- 13. Tuberomamillary nucleus -- 14. Posterior hypothalamic nucleus -- 15. Incerto hypothalamic cell group (A13) -- 16. Corpora mamillare -- 17. Conclusions -- 18. Summary -- 19. Acknowledgements -- 20. List of abbreviations -- 21. References -- Chapter III. Caudal Pons and Medulla Oblongata -- 1. Introduction -- 2 The concept of the reticular formation -- 3. Classification of lower brainstem neurons -- 4. Motoneurons with axons innervating striated muscle (somatic or special visceral) -- 5. Parasympathetic preganglionic motoneurons -- 6. Premotor neurons innervating brainstem motoneurons which project to striated muscle (somatic or special visceral) -- 7. Respiratory neurons in the lower brainstem. , 8. The raphe nuclei in the human -- 9. Lower brainstem neurons projecting to the spinal cord, including sympathetic premotor neurons -- 10. Brainstem catecholamine-synthesizing neurons -- 11. Neurons containing 5-HT, Neuropeptide Y, or Substance P -- 12. Neurons synthesizing nitric oxide in lower brainstem of human -- 13. Human ventrolateral medullary neurons containing PNMT, PH8 or NADPH diaphorase -- 14. Galanin-containing neurons in human medulla and pons -- 15. Nucleus tractus solitarius -- 16. Nerve terminals containing neurotransmitter-related markers in lower pons and medulla -- 17. Receptor binding studies in lower pons and medulla -- 18. Receptors on area postrema neurons and on distal processes of vagal afferents -- 19. Acknowledgements -- 20. References -- Chapter IV. The Primate Locus Coeruleus: The Chemical Neuroanatomy of the Nucleus, its Efferent Projections, and its Target Receptors -- 1. Introduction -- 2. The nucleus locus coeruleus -- 3. Afferents -- 4. Efferents -- 5. Receptors -- 6. Development -- 7. Conclusions -- 8. Acknowledgements -- 9. Abbreviations -- 10. References -- Chapter V. The Cholinergic System in the Primate Brain: Basal Forebrain and Pontine-Tegmental Cell Groups -- 1. Introduction -- A. The basal forebrain cholinergic system -- 1. Historical definition of the magnocellular basal nucleus -- 2. Cytoarchitectonic features of the basal forebrain cholinergic system in the primate brain -- 3. Expression of neurotrophin receptors by cholinergic cells of the basal forebrain -- 4. NADPH-diaphorase in the primate basal forebrain -- 5. Peptide coexpression in the cholinergic cells of the basal forebrain -- 6. Relation between the cholinergic and other classical neurotransmitter systems in the primate basal forebrain -- 7. Functional neuroanatomy of the basal forebrain cholinergic system. , 8. Pathology of the basal forebrain cholinergic system: aging and neurodegeneration in Alzheimer's and in Parkinson's diseases -- 9. Primate models of Alzheimer disease: experimental cholinergic denervation -- B. The pontomesencephalotegmental cholinergic cell groups in the primate brain -- 1. Introduction -- 2. Cytoarchitecture of the pedunculopontine tegmental area -- 3. Connections of the cholinergic PPT and LDT -- 4. Cholinergic cell groups in the parabrachial complex -- 5. Neuropathology of the mesopontine cholinergic system -- 6. References -- Chapter VI. Dopamine Systems in the Primate Brain -- 1. Introduction -- 2. Mesencephalon -- 3. DA Nigrostriatal system -- 4. DA Mesolimbic system -- 5. DA Mesocortical system -- 6. Development -- 7. Acknowledgements -- 8. References -- Chapter VII. Chemical Neuroanatomy of the Primate Insula Cortex: Relationship to Cytoarchitectonics, Connectivity, Function and Neurodegeneration -- 1. Introduction -- 2. Embryological development -- 3. Gross anatomy of the insula -- 4. Primate insula analysis -- 5. Insular connectivity -- 6. Insula chemoanatomy -- 7. Neuropeptides -- 8. Insular chemistry: effects of aging and neurodegenerative disorders -- 9. Overview of the chemoarchitecture of the insula -- 10. Functional implications -- 11. Insular involvement in pathologic disturbances -- 12. Acknowledgements -- 13. Abbreviations -- 14. References -- Chapter VIII. Primate Cingulate Cortex Chemoarchitecture and its Disruption in Alzheimer's Disease -- 1. Introduction -- 2. Cingulate cortex in Alzheimer's disease: overview of heterogeneity and subtypes -- 3. Dopaminergic architecture -- 4. Cholinergic architecture -- 5. Area 29 metabolism and acetylcholinesterase regulation of microvasculature -- 6. Chemoarchitectural organization of primate cingulate cortex -- 7. Acknowledgements -- 8. Abbreviations -- 9. References. , Subject Index.

Note: Front Cover -- Handbook of Chemical Neuroanatomy: Integrated Systems of the Cns, Part III -- Copyright Page -- Contents -- Chapter I. The cerebellum, chemoarchitecture and anatomy -- 1. Introduction -- 2. Cytology of the cerebellar cortex -- 3. Chemical anatomy of the cerebellar cortex -- 4. Gross anatomy of the mammalian cerebellum -- 5. The cerebellar nuclei -- 6. Efferent and afferent connections of the cerebellar cortex: corticonuclear, olivocerebellar and mossy fiber connections and cytochemical maps -- 7. Postscript -- 8. Acknowledgements -- 9. References -- Chapter II. The Basal Ganglia -- 1. Introduction -- 2. Organizational overview -- 3. Cerebral cortex input to striatum -- 4. Striatum -- 5. Globus pallidus (external segment) -- 6. Subthalamic nucleus -- 7. Substantia nigra/entopeduncular nucleus -- 8. Connectional organization of basal ganglia -- 9. Relationship between cortex and basal ganglia -- 10. Striatal patch/matrix compartments -- 11. Direct/indirect striatal output systems -- 12. Acknowledgements -- 13. References -- Chapter III. The Olfactory System -- 1. Introduction -- 2. The main olfactory bulb -- 3. Primary olfactory cortex -- 4. Integration of the main olfactory system with other functions -- 5. The accessory olfactory system -- 6. 'Non-olfactory' modulatory inputs to the olfactory system -- 7. Acknowledgments -- 8. Abbreviations -- 9. References -- Subject Index.

Note: Cover -- The Primate Nervous System, Part II -- Copyright -- List of Contributors -- Preface -- Contents -- Chapter I THE THALAMUS OF PRIMATES -- 1. Introduction -- 2. Basic subdivisions of the thalamus -- 3. Nuclear parcellation of the thalamus in representative primates -- 4. Histochemistry of the monkey and human thalamus -- 5. The cell types of the primate thalamus -- 6. Chemical identities of relay neurons -- 7. Basic circuitry of the primate thalamus -- 8. Neurotransmitters and their receptors in the thalamus -- 9. Regional projections of the thalamus -- 10. Thalamic nuclei as components of defined functional systems -- 11. Summary -- 12. Acknowledgments -- 13. Abbreviations -- 14. References -- Chapter II NEUROCHEMICAL ORGANIZATION OF THE PRIMATE VISUAL CORTEX -- 1. Introduction -- 2. General organization of primate visual cortex -- 3. Neurotransmitter links to cortical circuits: overview -- 4. Excitatory circuits -- 5. Inhibitory circuits: GABAergic interneurons -- 6. Monoaminergic and cholinergic innervation of primate visual cortex -- 7. Activity-dependent plasticity of neurotransmitters, receptors and other neurochemicals in adult monkey area V1 -- 8. Chemoarchitectonics: chemical markers of regional heterogeneity -- 9. Relationships between neurochemical phenotype, connectivity and human neuropathology: the visual cortex in Alzheimer's disease -- 10. Acknowledgements -- 11. References -- 12. Abbreviations -- SUBJECT INDEX.

Note: Cover -- TOCContents -- List of Contributors -- Preface -- CHChapter I. Somatostatin receptors -- 1. Introduction -- 2. Structural and biochemical properties -- 3. Localization of somatostatin binding sites in the central nervous system -- 4. Localization of somatostatin receptor subtypes -- 5. Somatostatin receptors in brain disorders -- 6. Perspectives -- 7. Abbreviations -- 8. Acknowledgements -- 9. References -- CHChapter II. Brain PACAP/VIP receptors: regional distribution, functional properties and physiological relevance -- 1. Introduction -- 2. Distribution of VIP and PACAP receptors -- 3. Molecular cloning and pharmacological characterization of VIP/PACAP receptors -- 4. Signal transduction -- 5. Trophic actions of VIP and PACAP -- 6. Involvement of VIP/PACAP in circadian rhythms and sleep -- 7. Regulation of brain energy metabolism by VIP -- 8. Modulation by VIP and PACAP of glutamate-mediated signalling in the cerebral cortex -- 9. Abbreviations -- 10. Acknowledgements -- 11. References -- CHChapter III. Localization of angiotensin receptors in the nervous system -- 1. Introduction -- 2. Localization of AT1 and AT2 receptors -- 3. Overview of AT1 receptor functions in selected brain regions -- 4. Conclusion -- 5. Abbreviations -- 6. Acknowledgements -- 7. References -- CHChapter IV. Brain endothelin and natriuretic peptide receptors -- 1. Why endothelin and natriuretic receptors? -- 2. Brain endothelin receptors -- 3. Brain natriuretic peptide receptors -- 4. References -- CHChapter V. Neuropeptide FF receptors -- 1. Introduction -- 2. Pharmacological activities of neuropeptide FF -- 3. Neuropeptide FF as a neurotransmitter -- 4. Neuropeptide FF receptors -- 5. Brain neuropeptide FF receptors in other species -- 6. Discussion -- 7. Abbreviations -- 8. Acknowledgements -- 9. References. , CHChapter VI. Neurokinin receptors in the CNS -- 1. Introduction -- 2. Discovery of the tachykinins -- 3. Distribution of tachykinin-like immunoreactivity -- 4. Physiological functions of tachykinins -- 5. CNS neurokinin receptors -- 6. Are tachykinins mostly involved in 'volume' transmission? -- 7. Conclusion -- 8. Abbreviations -- 9.Acknowledgements -- 10. References -- CHChapter VII. Brain kallikrein-kinin system: from receptors to neuronal pathways and physiological functions -- 1. Introduction -- 2. The kallikrein-kinin system -- 3. Regional distribution of the kallikrein-kinin system in the central nervous system -- 4. On the physiological role for kinins in central cardiovascular regulation -- 5. On the physiological role for kinins in the spinal cord -- 6. Other central effects of kinins -- 7. Considerations and perspectives -- 8. Conclusion -- 9. Abbreviations -- 10. Acknowledgements -- 11. References -- CHChapter VIII. Calcitonin gene-related peptide (CGRP), amylin and adrenomedullin: anatomical localization and biological functions in the mammalian and human brains -- 1. Discovery and genomic composition -- 2. Structure of CGRP and structure-activity relationships -- 3. Amylin -- 4. Adrenomedullin -- 5. Neuroanatomical localization -- 6. Biological activities -- 7. Conclusion and perspectives -- 8. Abbreviations -- 9. Acknowledgements -- 10. References -- CHChapter IX. Neuropeptide Y, peptide YY and pancreatic polypeptide receptor proteins and mRNAs in mammalian brains -- 1. Introduction -- 2. Biological effects of NPY and related peptides -- 3. NPY, PYY and PP receptor subtypes -- 4. Agonists and antagonists of the NPY family -- 5. NPY receptors in the rat brain -- 6. NPY receptor subtypes in other species -- 7. Interactions of NPY with various neuronal populations. , 8. Physiological and pathophysiological implications of NPY and its receptors -- 9. Conclusion -- 10. Abbreviations -- 11. Acknowledgements -- 12. References -- CHChapter X . Multiple brain corticotropin-releasing factor receptors and binding protein -- 1. Introduction and historical perspectives -- 2. CRF family of peptides -- 3. Neuroanatomy of the CRF family of peptides -- 4. CRF receptors and binding protein -- 5. Summary and conclusions -- 6. Acknowledgements -- 7. References -- IDXSubject Index.