Publication Date:
2014-07-02
Description:
A tetrameric N-acetyl galactosaminyl (GalNAc) peptidomimetic was constructed by N-acetylation of repeating proline-based hydroxamic acid units, followed by a convergent ‘click chemistry’ coupling. This novel glycopeptidomimetic was determined to effectively antagonize the interaction between a transmembrane hepatic lectin and GalNAc on the cellular level. Scientific Reports 4 doi: 10.1038/srep05513
Electronic ISSN:
2045-2322
Topics:
Natural Sciences in General
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