GLORIA

GEOMAR Library Ocean Research Information Access

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    STUDY OF BURN TOXINS (1968)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 150 (1968), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Notes: A review has been presented of our studies on burn toxins from mouse skin. Sterile homogenates of mouse skin burned in vitro at 250°C rapidly induce neurological disturbances and eventually cause death when injected into normal mice. Such phenomena are not observed with homogenates of unburned skin.The toxic properties of burned mouse skin are apparently unrelated to bacterial factors and may be attributed to heat induced changes in components of normal skin.Preliminary studies on the isolation and characterization of the toxic material have been carried out. It is suggested that the toxic material contains protein and lipid components essential for its activity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1968.tb14732.x
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Die posttraumatische respiratorische Insuffizienz (1971)
    Springer
    Langenbeck's archives of surgery 330 (1971), S. 1-9 
    Details
    ISSN: 1435-2451
    Keywords: Respiratory Insufficiency ; Ventilation-Perfusion Inequality ; Shunt ; Deadspace ; Silent Unit ; Alveolo-Arterial Oxygen Gradient ; Interstitial Edema ; 2,3 DPG ; Respiratory Function Tests
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The pathophysiology of pulmonary and extrapulmonary respiratory changes which follow trauma are reviewed and simple diagnostic measures given for their early bedside recognition. Posttraumatic respiratory insufficiency which has become the major cause of death of patients in shock develops primarely on the basis of ventilation-perfusion inequalities: e.g. shunt, deadspace and silent unit. Daily measurements of the alveoloarterial oxygen gradient (AaDO2) in severely ill patients helps to recognizeshunt flow by simple means in an early state when therapeutic measures are still successful. Thedeadspace to tidal volume relation (VD/VT) increases after injury as result of plateletaggregation and hemorrhage.Transcapillary fluid loss is often a consequence of beginning left heart failure, hypoproteinemia (hemodilution due to excessive administration of colloid free solutions), aspiration and high positive airwaypressures or oxygen concentrations during artificial respiration. Deficiences in oxygen transport have lately been discussed with increasing emphasis. Some remarks regarding 2,3 DPG-levels of stored blood and viscosity changes after volume replacement are added.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01230639
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    194. Hämodilution (1978)
    Springer
    Langenbeck's archives of surgery 347 (1978), S. 677-678 
    Details
    ISSN: 1435-2451
    Keywords: Surgery elective ; Autologous blood ; Blood, saving ; Transfusion, risks ; Elektive Chirurgic ; autologes Blut ; Einsparung ; Transfusionsrisiken
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Hämodilution (HD) wird durch Blutentzug und simultanen isovolämischen Ersatz durch langwirksame Kolloide induziert. Bei intraoperativem Blutverlust sind als Folge der HD die Erythrocytenverluste geringer. Das entzogene, autologe Blut wird während oder am Ende des chirurgischen Eingriffes retransfundiert. Hauptziel der präoperativen HD ist, den irreversiblen Verlust von Erythrocyten möglichst gering zu halten. Durch these Methode kann in der elektiven Chirurgie bei zahlreichen Patienten auf die Transfusion von Spenderblut verzichtet werden. Der Film demonstriert die physiologischen Mechanismen, welche die Adaption an den reduzierten Hämatokrit erlauben; die Indikationen, Kontraindikationen und Vorteile dieses Alternativverfahrens zur Bluttransfusion werden dargestellt.
    Notes: Summary Gradual removal and simultaneous replacement of blood with equal volumes of long-lasting colloids result in hemodilution. Consequently blood lost during operation contains fewer red cells. The autologous blood removed is retransfused in reverse order during and after surgery. The principal aim of preoperative hemodilution is to keep the irreversible loss of autologous red cells down to the lowest possible level. By this method, the transfusion of donor blood can be avoided in numerous patients undergoing elective surgery. The film illustrates the physiologic mechanisms that permit adaptation to the intentional reduction in hematocrit and outlines the indications, contraindications, and advantages of this principle.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01579487
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Clinical research in thromboembolism: What is important for the urologist? (1977)
    Springer
    Urological research 5 (1977), S. 49-50 
    Details
    ISSN: 1434-0879
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00256840
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Das Verhalten intraoperativ entstandener tiefer Venenthrombosen, beurteilt anhand wiederholter Phlebographien (1976)
    Springer
    Journal of molecular medicine 54 (1976), S. 521-526 
    Details
    ISSN: 1432-1440
    Keywords: Deep vein thrombosis ; phlebography ; postoperative ; fibrinogen test ; postthrombotic syndrom ; Tiefe Venenthrombose ; Phlebographie ; postoperativ ; Fibrinogentest ; postthrombotisches Syndrom
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Im Rahmen einer prospektiven, randomisierten und kontrollierten Studie, in der die Thromboseprophylaxe-Mittel Dextran und Heparin bei allgemein-chirurgischen und urologischen Patienten geprüft werden, phlebographierten wir 31 Patienten mit sicherer tiefer Venenthrombose sofort nach der Diagnosestellung mittels125J-Fibrinogentest. 16 Patienten wurden 14 Tage später ein zweites Mal phlebographiert.Alle Thromben entstanden intraoperativ. 24 von 31 Patienten zeigten einemultifokale Entstehung der Thromben. Unabhängig vom Prophylaxe-Mittel und der eingeleiteten Therapie machten die Thromben in den ersten 14 Tagen nach deren Entstehung folgende Veränderungen durch: 9 retrahierten sich, 6 verschwanden, ohne Wandveränderungen aufzuweisen, und 1 verschloß das befallene Gefäß noch vollständig. 2 Thromben verschwanden ohne jegliche Therapie; 4 weitere unter Heparin- und/oder Phenprocoumonbehandlung.
    Notes: Summary Phlebography was carried out in a prospective randomised, controlled study during which dextran and small doses of s.c. heparin have been compared in general surgical and urological patients, in 31 persons with proven deep vein thrombosis diagnosed with the125I-fibrinogen test. In 16 out of the 31 patients a second phlebogram could be performed two weeks later. In this study all thrombi occurred intraoperatively. In 24 of the 31 patients, the appearance of thrombi was multilocular. Independent of the prevention instituted and irrespective of the therapy, the following phenomena could be seen 14 days after the first phlebogram: 9 thrombi retracted, 6 disappeared completely and 1 occluded the vein completely. 2 thrombi disappeared without any therapy whatsoever, the 4 others disappeared in patients receiving heparin and/or coumarin for treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01468973
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Prevention of thromboembolic complications with miniheparin-dihydroergotamine in patients undergoing lumbar disc operations (1984)
    Springer
    European archives of psychiatry and clinical neuroscience 234 (1984), S. 157-161 
    Details
    ISSN: 1433-8491
    Keywords: Lumbar disc ; Heparin ; Thromboembolism ; Dihydroergotamine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have evaluated the incidence of bleeding complications using miniheparin(2 × 2500IU daily)-dihydroergotamine starting preoperatively in a randomized, controlled, prospective, double-blind study in 50 patients undergoing herniated lumbar disc operations. There was no difference in the incidence of intraoperative bleeding problems between the two groups. Preoperatively, 13 patients have been treated in another hospital with conventional low-dose heparin, and of these 13 patients, 7 developed bleeding complications. There were two deep wound hematomas in the placebo group. Early removal of stitches or operative revision of the wound was not necessary in either group. We conclude that the use of minidose heparin-dihydroergotamine is feasible for the prevention of thromboembolic complications in patients undergoing herniated lumbar disc operations, since an increased incidence of bleeding complications was not observed. This preventive method should therefore be further clinically evaluated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00461554
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Mezlocillin prophylaxis in biliary tract surgery. Results of a retrospective and a prospective trial (1982)
    Springer
    Infection 10 (1982), S. S144 
    Details
    ISSN: 1439-0973
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Alle Patienten, die im Jahre 1979 einer Gallenoperation unterzogen wurden, sind in die Studie einbezogen. In diesem Jahr konnte jeder Operateur postoperativ Antibiotika verabreichen, wenn er es für nötig erachtete. 39% von 71 Kranken erhielten postoperativ Antibiotika. 1980 erhielten 50 über 50 Jahre alte Patienten 36 Stunden lang prophylaktisch Mezlocillin, wenn sie einer Gallenoperation elektiv oder als Noteingriff unterzogen wurden. Lediglich 8% von ihnen benötigten postoperativ Antibiotika. Verglichen mit den 39% des Jahres 1979 ist diese Differenz statistisch hochsignifikant. Diese Pilot-Studie rechtfertigt weitere Untersuchungen, ob eine Mezlocillin-Einmaldosis-Prophylaxe infektiöse Komplikationen, die Zeit des Hospitalaufenthalts und den Antibiotika-Gesamtverbrauch reduzieren kann.
    Notes: Summary We have evaluated the case histories of all patients who underwent surgery of the biliary tract in 1979. In that year every surgeon was able to administer antibiotics postoperatively whenever he considered it necessary. Of the 71 patients, 39% received postoperative antibiotic treatment. In 1980, 50 patients over the age of 50 received a 36-hour course of mezlocillin prophylaxis when they underwent surgery of the biliary tract, either as an elective or emergency operation. Only 8% of these patients required antibiotics postoperatively. In comparison to the 39% from 1979, this difference is highly significant statistically. This pilot study justifies further investigations to determine whether single-dose mezlocillin prophylaxis is able to reduce the incidence of infectious complications, the duration of the hospital stay and the total amount of antibiotics administered.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01640659
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    The influence of temperature on the volume effect of dextran 70 (1967)
    Springer
    Clinical and experimental medicine 144 (1967), S. 217-221 
    Details
    ISSN: 1591-9528
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Nach Entzug von 500 ml Blut wurde bei elf gesunden Freiwilligen die Zuverlässigkeit der Volumenexpansion einer Infusion von 500 ml 6% Dextran 70 (Macrodex®) in 0,9% Kochsalzlösung in Abhängigkeit von der Temperatur geprüft. Die Veränderungen des Blutvolumens wurden mittels der Volemetron-RI131HSA-Hämatokrittechnik gemessen. Sowohl die Infusion von kalter (4°C) als auch von warmer (20°C) Dextranlösung führt zu einer initialen Volumenzunahme, die größer ist, als der zugeführten Menge entspricht. 3 Std nach Infusionsbeginn entspricht das Blutvolumen in beiden Gruppen dem Wert vor dem Blutentzug. Die Temperatur der Infusionslösung beeinflußt im Bereich von 4–20°C den Volumeneffekt von Dextran 70 bei hypovolämischen Erwachsenen wahrscheinlich nicht.
    Notes: Summary The reliability of an infusion of 500 ml cold or room temperature 6% dextran 70 in normal saline as a volume expander was studied in eleven subjects after removal of 500 ml blood. Changes in blood volume were measured directly with the Volemetron-RI131HSA technique and indirectly from changes in hematocrit. Both the cold and warm solutions lead to an immediate volume increase higher than the amount infused. 3 h after infusion the blood volume in both groups had reached the initial value. It is concluded that the temperature of the infusion solution between 4°C–20°C probably does not influence the volume effect of 6% dextran 70 in hypovolemic man.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02043200
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    228. Thromboembolie-Prophylaxe (1981)
    Springer
    Langenbeck's archives of surgery 355 (1981), S. 611-611 
    Details
    ISSN: 1435-2451
    Keywords: Pulmonary embolism ; Thrombosis ; Prophylaxis ; Heparin ; Lungenembolie ; Thrombose ; Prophylaxe ; Heparin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Postoperative Frühmobilisierung, Physiotherapie, Beinhochlagerung und elastische Binden sind nicht in der Lage, die Häufigkeit tiefer Venenthrombosen (TVT) zu reduzieren. Graduierte Kompressionsstrümpfe und intermittierende Kompression der Wadenmuskulatur vermögen die Anzahl TVT zu reduzieren, aber es gibt keine Beweise dafür, daß sie auch die Anzahl tödlicher Lungenembolien (LE) vermindern können. Auch für aggregationshemmende Substanzen gibt es keine solchen Beweise. Perorale Cumarinderivate, kleine Dosen Heparin und i.v. Dextran-Infusionen reduzieren die Anzahl TVT und tödlicher LE. Alle 3 Methoden haben Vor- und Nachteile. 2 × 5 000 IE Heparin täglich mit prdoperativem Beginn sind wirksam.
    Notes: Summary Postoperative early mobilization, physiotherapy, leg elevation, and elastic bandages are unable to reduce the incidence of deep-vein thrombosis (DVT). Graduated compression stockings and intermittent compression of calf muscles can reduce the amount of DVT, but there are no data that they can also decrease the incidence of fatal pulmonary embolism (PE). For antiplatelet substances there is also no such proof. Peroral cumarin derivatives, small doses of heparin, and i.v. dextran do reduce the incidence of DVT and PE. All three methods have advantages and disadvantages. Daily administration of 2 × 5 000 IU heparin with a preoperative start is effective.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01287061
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Der Volumeneffekt verschiedener Plasmaersatzstoffe (1962)
    Springer
    Langenbeck's archives of surgery 301 (1962), S. 128-135 
    Details
    ISSN: 1435-2451
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Nach Bestimmung eines ersten Blutvolumens und Entnahme von 400 ml Blut wurde der Volumeneffekt von 500 ml Macrodex® (6% Dextran), Haemaccel® (3,5% Gelatine) oder Physiogel® (4,2% Gelatine) an je 10 gesunden Versuchspersonen mit Hilfe des Volemetrons gemessen. Bei der dritten Blutvolumenbestimmung, 21/2 Std nach Infusionsende, betrug das „ersetzte Volumen” bei Macrodex 105%, bei Haemaccel 49% und bei Physiogel 36% (P kleiner als 0,05 gegenüber Macrodex) der infundierten Expandermenge. Die Gesamturinausscheidung betrug 252 ml in der Macrodex-, 431 ml (P kleiner als 0,05) in der Haemaccel- und 498 ml (P kleiner als 0,01) in der Physiogel-Gruppe.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02434599
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...