ISSN:
1573-9171
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Conclusions 1. The stability of the tetramethylpiperidine molecular ion is reduced by the presence of the methyl substituents in the molecule. The (M-5)+ ion peak has maximum intensity in the mass spectrum of this compound. 2. The presence of a NH2 group at position 4 in the tetramethylpiperidine molecule tends to destabilize the molecular ion, but the presence of a β-aminoethyl group has no appreciable effect on the character of the fragmentation. 3. Maximum stabilization of the molecular ion in the presence of electron-acceptor ethylsulfonyl groups at position 4 is through loss of these groups rather than through elimination of the ĊH3 radical. 4. Substitution of one of the hydrogens attached to the nitrogen by an oxylated group alters the tetramethylpiperidine fragmentation pattern: the ĊH3 radicals migrate to the N.−O group in the molecular ion, and the ring breaks with elimination of the N-O group. 5. Introduction of either electron-donor or electron-acceptor substituents principally affects the radical fragmentation pattern, but causes little change in the decomposition of the C4-substituted tetramethylpiperidines.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00925051
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