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  • 1
    Online Resource
    Online Resource
    Processing Ceramics from Waste : a New Raw Material Source for a Global Change. (2016)
    Zurich :Trans Tech Publications, Limited,
    Details
    Keywords: Electronic books.
    Description / Table of Contents: Selected, peer reviewed papers from the International Workshop on "Processing Materials from Waste", September 29 - October 1, 2014, Baeza, Spain.
    Type of Medium: Online Resource
    Pages: 1 online resource (172 pages)
    Edition: 1st ed.
    ISBN: 9783035700657
    Series Statement: Key Engineering Materials Series ; v.Volume 663
    URL: https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=4415125
    Language: English
    Note: Intro -- Processing Ceramics from Waste: A New Raw Material Source for a Global Change -- Preface and Sponsor -- Table of Contents -- Chapter 1: New Developments from Waste -- Processing Clinker from Wastes: A New Raw Material Source for a Global Change -- Vitreous and Ceramic Processing for the Recycling of Industrial Wastes -- Life Ceram - Zero Waste in Ceramic Tile Manufacture -- Production of Cement Blocks and New Ceramic Materials with High Content of Glass Waste -- Bacterial Induced Cementation Processes and Mycelium Panel Growth from Agricultural Waste -- Influence of BFS Content in the Mechanical Properties and Acid Attack Resistance of Fly Ash Based Geopolymers -- Production of Ceramic Materials Using only Waste as Raw Materials -- Chapter 2: Waste Incorporation in Traditional Materials -- Manufacture of Ceramic Bodies by Using a Mud Waste from the TiO2 Pigment Industry -- Study of Waste from Two-Phase Olive Oil Extraction as an Additive in Ceramic Material -- Production of Ceramic Material Using Wastes from Brewing Industry -- Lighter Structural Clay Ceramics Manufactured with Marble Cutting Dust and Paperboard Based Packaging Waste -- Study of the Mechanical Properties of Concrete with Sisal and Polypropylene Fibers -- Chapter 3: Analysis of Waste, Materials Properties and Production -- The Future of Research in Ceramics in the XXI Century -- Energy-Environmental Diagnosis of the Ceramic Sector Companies in the Metropolitan Area of Cucuta, Norte de Santander, Colombia -- Physic-Chemical Characterization of a Waste from Olive Industry -- Application of Translucent Concrete for Lighting Purposes in Civil Infrastructures and its Optical Characterization -- Extracting Metals with Carbon Nanotubes: Environmental Possibilities -- Keywords Index -- Authors Index.
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  • 2
    Online Resource
    Online Resource
    Guía práctica para implementar la economía circular en las pymes. (2020)
    Madrid :AENOR Internacional, S.A.U.,
    Details
    Keywords: Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (201 pages)
    Edition: 1st ed.
    ISBN: 9788417891275
    URL: https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=29383365
    Language: Spanish
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    GEOMAR EBL
  • 3
    Electronic Resource
    Electronic Resource
    Metastasis to the Male Breast from Hypopharyngeal Squamous Cell Carcinoma (2005)
    Oxford, UK : Blackwell Publishing Ltd
    The @breast journal 11 (2005), S. 0 
    Details
    ISSN: 1524-4741
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1075-122X.2005.00139.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Bcl-xL blocks mitochondrial multiple conductance channel activation and inhibits 6-OHDA-induced death in SH-SY5Y cells (2004)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 89 (2004), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Apoptosis is an active process that is regulated by different signalling pathways. One of the more important organelles involved in apoptosis regulation is the mitochondrion. Electron chain transport disruption increases free radical production leading to multiple conductance channel opening, release of cytochrome c and caspase activation. This death pathway can be blocked by anti-apoptotic members of the Bcl-2 protein family that might shift redox potential to a more reduced state, preventing free radical-mediated damage. 6-Hydroxydopamine (6-OHDA) has been widely used to generate Parkinson's disease-like models. It is able to generate free radicals and to induce catecholaminergic cell death. In this paper we have used the human neuroblastoma cell line SH-SY5Y overexpressing Bcl-xL as a model to gain insights into the mechanisms through which Bcl-xL blocks 6-OHDA-induced cell death and to identify the molecular targets for this action. Herein, we present evidence supporting that the Bcl-xL–anti-apoptotic signal pathway seems to prevent mitochondrial multiple conductance channel opening, cytochrome c release and caspase-3 like activity following 6-OHDA treatment in the human neuroblastoma cell line SH-SY5Y.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1471-4159.2003.02299.x
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  • 5
    Electronic Resource
    Electronic Resource
    Stressor-related impairment of synaptic transmission in hippocampal slices from α-synuclein knockout mice (2004)
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 20 (2004), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The role of alpha-synuclein (α-Syn) has recently received considerable attention because it seems to play a role in Parkinson's disease (PD). Missense mutations in the α-Syn gene were found in autosomal dominant PD and α-Syn was shown to be a major constituent of protein aggregates in sporadic PD and other synucleinopathies. Under normal conditions, α-Syn protein is found exclusively in synaptic terminals. However, the potential participation of alpha-synuclein in maintaining and regulating synaptic efficacy is unknown. We have investigated the excitatory synaptic modulation of alpha-synuclein in CA1 pyramidal neurons, using the in vitro hippocampal slice technique. The 4-aminopyridine-induced increase of both spontaneous excitatory postsynaptic current (EPSC) frequency and amplitude was significantly higher in α-Syn wild-type than knockout mice, whereas basal spontaneous EPSC frequency and amplitude was similar in both animals. As the spontaneous synaptic activity was abolished by tetrodotoxin, which indicates that it was a result of action potential-mediated transmitter release from presynaptic terminals, spontaneous EPSC changes observed in α-Syn knockout mice suggest that these animals present a modification of synaptic transmission with a presynaptic origin. Presynaptic depression of evoked EPSCs by hypoxia or adenosine was significantly larger in α-Syn knockout than in wild-type mice, further supporting the hypothesis of regulation of synaptic transmission by α-Syn. Together, these observations indicate that the loss of α-Syn reduces synaptic efficacy when the probability of transmitter release is modified. We conclude that α-Syn might have important actions on the maintenance of the functional integrity of synaptic transmission and its regulation in hippocampus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-9568.2004.03801.x
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  • 6
    Electronic Resource
    Electronic Resource
    Chromaffin cell death induced by 6-hydroxydopamine is independent of mitochondrial swelling and caspase activation (2003)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 84 (2003), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Our results provide evidence that 6-hydroxydopamine induced, after auto-oxidation, toxic levels of hydrogen peroxide (H2O2) that caused bovine chromaffin cell toxicity and death. 6-Hydroxydopamine (6-OHDA) treatment markedly reduced, in a dose–response fashion, chromaffin cell viability. Cell death was accompanied by cell shrinkage, nuclear condensation and DNA degradation. Under our experimental conditions, 6-OHDA auto-oxidation formed quinones and reactive oxygen species (ROS) that mainly contributed to 6-OHDA-induced cytotoxicity in bovine chromaffin cells. Accordingly, different antioxidants, including catalase, vitamin E, Mn(IIItetrakis(4-benzoic acid)porphyrin chloride (MnTBAP) or ascorbic acid, provided protection against 6-OHDA-induced toxicity. Further evidence that 6-OHDA induces oxidative stress is provided by the fact that this compound decreased total mitochondrial reduced NAD(P)H levels. Our results also suggest that mitochondrial swelling and caspase activation do not play a direct role in 6-OHDA-induced death in bovine chromaffin cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1471-4159.2003.01592.x
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  • 7
    Electronic Resource
    Electronic Resource
    A note on the resistance of Bacillus spp., faecal streptococci and Salmonella typhimurium to an inhibitor of Clostridium spp. formed by heating sodium nitrite (1973)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of food science & technology 8 (1973), S. 0 
    Details
    ISSN: 1365-2621
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: An inhibitor of Clostridium spp. formed by autoclaving sodium nitrite in a laboratory medium also inhibited at pH 6·0 nine of fourteen strains of Bacillus spp. B. circulans, B. polymyxa, B. macerans, B. pantothenticus and Bacillus F were resistant. Streptococcus durans was inhibited but Strep. faecium, Strep. faecalis and Strep. faecalis var. zymogenes were not. Salmonella typhimurium was not inhibited.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.1973.tb01733.x
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Contact dermatitis from the staples of neuroreflexotherapy (2004)
    Oxford, UK; Malden, USA : Munksgaard International Publishers
    Contact dermatitis 51 (2004), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0105-1873.2004.0424i.x
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Quality assessment of the human genome sequence (2004)
    [s.l.] : Macmillian Magazines Ltd.
    Nature 429 (2004), S. 365-368 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] As the final sequencing of the human genome has now been completed, we present the results of the largest examination of the quality of the finished DNA sequence. The completed study covers the major contributing sequencing centres and is based on a rigorous combination of laboratory experiments ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nature02390
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Effects of histamine H3 receptor ligands in experimental models of anxiety and depression (1999)
    Springer
    Psychopharmacology 142 (1999), S. 215-220 
    Details
    ISSN: 1432-2072
    Keywords: Key words Histamine H3 receptor ; R-α-methylhistamine ; Thioperamide ; Clobenpropit ; Anxiety ; Depression
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Histamine H3 receptor ligands have been proposed to be of potential therapeutic interest for the treatment of different central nervous system disorders; however, the psychopharmacological properties of these drugs have not been studied extensively. In this work, we investigated the possible involvement of histamine H3 receptor function in experimental models of anxiety (elevated plus-maze) and depression (forced swimming test). Male Sprague-Dawley rats were treated IP with the histamine H3 receptor agonist R-α-methylhistamine (10 mg/kg) or the histamine H3 receptor antagonist thioperamide (0.2, 2 and 10 mg/kg) and 30 min afterwards the time spent in the open arms of an elevated plus-maze was registered for 5 min. The immobility time of male OF1 mice in the forced swimming test was recorded for 6 min, 1 h after the IP administration of R-α-methylhistamine (10 and 20 mg/kg), thioperamide (0.2, 2, 10 and 20 mg/kg) or another histamine H3 receptor antagonist, clobenpropit (5 mg/kg). The locomotor activity of mice was checked in parallel by means of an activity meter. Both saline controls and active drug controls were used in all the paradigms. Neither thioperamide nor R-α-methylhistamine significantly changed animal behaviour in the elevated plus-maze. R-α-methylhistamine and the higher dose of thioperamide assayed (20 mg/kg) were also inactive in the forced swimming test. By contrast, thioperamide (0.2–10 mg/kg) dose-dependently decreased immobility, the effect being significant at 10 mg/kg (33% reduction of immobility); clobenpropit produced an effect qualitatively similar (24% reduction of immobility). None of these histamine H3 receptor antagonists affected locomotor activity. These preliminary results suggest that the histamine H3 receptor blockade could be devoid of anxiolytic potential but have antidepressant effects. Besides, the stimulation of these receptors does not seem to be followed by changes in the behavioural parameters studied.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002130050882
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