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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Radiation and environmental biophysics 17 (1979), S. 67-83 
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Summary Tests of surgical treatments (graft of small intestine, and partial enter ectomy before or after irradiation) and dietetic treatments (continuous parenteral feeding) were carried out on 80 pigs irradiated over the posterior half of the body with doses of between 950 and 1750 rad at mid plane. The results relate to clinical symptoms, survivals, haematology, and histopathology; nutritional aspects were studied by means of evaluation of balances (nitrogen, lipids, and minerals) and absorption tests (58Co - Vit. B 12 and iodised lipids). Above 1200 rad recuperation of the digestive system did not in general make prolonged survival possible; in addition to intestinal lesions, renal and especially pancreatic atrophy appeared, whose consequences appeared to be determinative as regards the nutrition and hence the survival of the animals.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé De janvier 1989 à mai 1992, 70 transplantations hépatiques orthotopiques (THO) ont été faites chez 69 malades, dont 53 avaient une cirrhose (77%). Onze patients (16%) avaient une thrombose portale (TP) partielle ou totale préopératoire. Dix d'entre eux avaient une cirrhose d'étiologie variée. La TP totale a été diagnostiquée en préopératoire dans les trois cas. Au contraire, la TP partielle n'a été dépistée en préopératoire que dans trois des huit cas. Chez les cinq autres patients, la TP partielle a été découverte en peropératoire lors de la dissection de la veine porte. Le traitement chirurgical de la TP a consisté en une thrombectomie dans 10 cas suivie d'une anastomose portale terminolatérale conventionelle dans neuf cas et d'une anastomose entre la veine porte du greffon et la jonction spléno-mésentérique dans un cas. Une anastomose atypique entre la veine porte du greffon et une veine cholédocienne dilatée a été utilisée dans un cas de TP totale. Il n'y pas eu de décès ou de complication liée à l'existence d'une TP préopératoire. Une patiente est décédée au cinquième jour postopératoire d'une non fonction du primaire greffon. Un malade a été retransplanté au troisième moin en raison d'une thrombose de l'artère hépatique. Il y a eu deux décès secondaires par récidive cancéreuse à trois et sept mois. Huit patients sont vivants avec un recul de 4–39 mois après la THO. Nos conclusions à partir de cette série sont que: 1) la prévalence de la TP préopératoire chez les patients transplantés pour cirrhose avancée peut être élevée (19% des cirrhotiques dans cette série), 2) la TP est souvent partielle et, alors, difficile à diagnostiquer en préopératoire, 3) la TP, même totale, peut être traitée avec succès au cours de la THO et elle ne semble pas affecter la survie.
    Abstract: Resumen Se realizaron 70 trasplantes ortotópicos de hígado (TOH) entre enero de 1989 y mayo de 1992 en 69 pacientes, 53 (77%) de los cuales tenían cirrosis. Once pacientes (16%) presentaban preoperatoriamente trombosis total o parcial de la vena porta (TVP). Diez de estos pacientes tenían cirrosis de diversas causas. La TVP era total en tres casos y parcial en ocho; la TVP total fue detectada en todos los tres casos pero, en constraste, la TVP parcial fue diagnosticada preoperatoriamente en sólo tres de los ocho casos; en los otros cinco se descubrió la obstrucción en el curso de la disección de la vena porta. El manejo quirurgico de la TVP consistió en flebotrombectomía en diez casos seguida de la anastomosis portal término-terminal usual en nueve y anastomosis de la vena porta del injerto a la confluencia esplenomesentérica en uno. Anastomosis atípica de la vena porta del injerto a una vena coledociana dilatada fue practicada en un caso en TVP total. No se registraron muertes o complicaciones atribuibles a la presencia preoperatoria de TVP o a su manejo. Un paciente murió a los 5 días postoperatorios debido a falla en la función del injerto. Un paciente que desarrolló trombosis arterial tres meses después del TOH y fue exitosamente retrasplantado. Dos pacientes murieron por carcinoma recurrente a los tres y siete meses después del TOH, y ocho se encuentran vivos a los 4–39 meses. En cuanto a esta série, nuestras conclusiones son 1) la prevalencia de TVP preoperatoria en los pacientes trasplantados por cirrosis avanzada puede ser alta (19% de los cirrótico en esta serie), 2) la TVP frecuentemente es parcial y difícil de diagnosticar preoperatoriamente, 3) la TVP, aun si es total, puede ser manejada exitosamente en el curso de la cirugía y no parece afectar la supervivencia.
    Notes: Abstract From January 1989 to May 1992, 70 orthotopic liver transplantations (OLT) were performed in 69 patients, 53 of whom had cirrhosis (77%). Eleven patients (16%) had preoperative partial or total portal vein thrombosis (PVT). Ten of these patients had cirrhosis of various causes. PVT was total in three cases and partial in eight. Total PVT was detected preoperatively in all three cases. By contrast, partial PVT was diagnosed preoperatively in only three of the eight cases. In the five other cases of partial PVT, the obstruction was discovered intraoperatively during dissection of the portal vein. Surgical management of PVT consisted of phlebothrombectomy in ten cases followed by usual end-to-end portal anastomosis in nine cases and anastomosis of the graft's portal vein to the splenomesenteric confluence in one case. Atypical anastomosis of the graft's portal vein to a dilated choledocal vein was performed in one case of total PVT. There were no deaths or complications related to the presence of preoperative PVT or to its management. One patient died postoperatively of primary graft nonfunction at day 5. One patient had arterial thrombosis 3 months after OLT and was successfully retransplanted. Two patients died of recurrent carcinoma 3 and 7 months after OLT. Eight patients are alive 4 to 39 months after OLT. We conclude from this series that (1) the prevalence of preoperative PVT among patients transplanted for advanced cirrhosis may be high (19% of the cirrhotics in this series); (2) PVT is often partial and so difficult to diagnose preoperatively; (3) PVT, even when total, can be managed successfully during surgery and does not seem to affect survival.
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Intensive care medicine 8 (1982), S. 193-196 
    ISSN: 1432-1238
    Keywords: Intra abdominal abscess ; Abdominal surgery ; Computed tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Thirty-one patients were prospectively studied and had abdominal computed tomography for post laparotomy sepsis. Computed tomography is of particular interest in seriously ill post-operative patients, 15 of our patients were on ventilators, and it enabled diagnosis and localization of abscesses in 15 patients. Drainage could therefore be achieved via a limited surgical approach, and extensive laparotomy was avoided. Of 16 patients without abscess, the abdominal computed tomogram was negative in 14 cases and there were two false positives. The overall accuracy was 0.94 with a sensitivity of 1 and a specificity of 0.88. The ability to screen the whole abdomen and exactly localize the lesion are the advantages of this non-invasive method.
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Intensive care medicine 11 (1985), S. 107-109 
    ISSN: 1432-1238
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1248-9204
    Keywords: Incisional hernia ; Adhesion prevention ; Mesh ; Clinical trial
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Complete and rapid cellular ingrowth is the necessary condition of an ideal parietal mesh. However, this property obtained with conventional meshes induces visceral adhesion formation in 80 to 100% of the cases when the mesh is intraperitoneally implanted. In order to combine both cellular ingrowth on one side and adhesion prevention on the other, a new generation of polyester mesh protected by a hydrophilic absorbable film has been developed. The purpose of this study was to assess the performance and tolerance of this mesh in clinical use. 80 patients (mean age: 58 ± 12 y) were included in a prospective multicenter clinical trial: 75% for incisional hernia, 25% for umbilical hernia. Patients were treated via an open approach (64%) or laparoscopically (36%). All meshes were implanted in a midline intraperitoneal location. The main outcome was to evaluate the antiadhesive capability of the mesh as regards the viscera. In order to objectively assess the absence of visceral adhesion, a specific ultrasound (US) examination was firstly validated (preoperative prediction vs. operative findings) and secondly used during follow-up as well as usual the clinical parameters. Pre-op US prediction vs. per-op macroscopic findings: sensitivity 77%, specificity 74%, overall accuracy 75%, negative predicive value 84% (probability illustrating that a negative test really identified an adhesion-free patient). After two months, 80% of the patients were ultrasonically adhesion-free (88% in the laparoscopic group, 76% in the open surgery group, 77% in the incisional hernia group, 88% in the umbilical hernia group). Early postoperative complications were: seroma/hematoma 16.25%, subcutaneous infection 3.7%, cutaneous necrosis 2.5% and obstructions (outside the mesh) 2.5%. No mortality was observed. Clinically, after 10 months, no complication related to postoperative adhesions to the mesh was observed: (obstruction 0%, fistula or sepsis 0%). The observed recurrence rate was 2.5%. The intermediate results obtained in this prospective multicenter clinical trial demonstrated the safety and efficiency of this composite mesh in the intraperitoneal treatment of both incisional and umbilical hernia.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1248-9204
    Keywords: Hernia repair ; Laparoscopy ; Complications ; Neuralgia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The aim of our retrospective study was to quantify the incidence of chronic pain and cutaneous sensory changes among various anterior and posterior hernia repairs and then to compare laparoscopic with open techniques. A detailed questionnaire was sent in January 1998 to patients operated on from 1992 to 1996. Patients had to record their current parietal status and assess the result from their personal point of view. The replies were recorded without any medical adjustment. Of 545 patients treated for 617 groin hernias, 490 were followed for 1 to 5 years (median 3 years, 2 months). One hundred and ten patients (23%) experienced symptoms persisting for more than one year, including 50 cases of cutaneous sensory changes and 71 cases of pain. Twenty-four patients (5%) assessed their discomfort as more troublesome than the hernia they had before, overriding the benefits of a solid repair. There was no statistical difference concerning the incidence of chronic pain between the nonprosthetic and prosthetic (“tension-free”) subgroups or between the open and laparoscopic subgroups. Forty-five of 50 cutaneous sensory changes occurred after the inguinal approach. The incidence of such changes was 10 times lower in the laparoscopic than in the open subgroup (p〈0.001). Our study confirms that pain and sensory changes are more frequent and persistent than generally estimated and that they can interfere with the patient's daily life. Posterior approaches, in particular laparoscopic, were associated with statistically fewer sensory changes than inguinal approaches. These results suggest using questionnaires about the quality of life when evaluating hernia repair.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    International journal of colorectal disease 8 (1993), S. 29-33 
    ISSN: 1432-1262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé 440 malades ont été inclus prospectivement dans un essai multi-centrique randomisé afin de comparer 4 types de sutures manuelles avec un fil lentement résorbable (84 sutures termino-terminales à points séparés, 77 termino-terminales par sujet, 82 latéro-terminales à points séparés et 91 termino-latérales par sujet) et une variété d'anastomoses mécaniques (106 sutures latéro-latérales aux pinces GIA + TA). Il s'agissait d'anastomoses iléo-coliques après hémicolectomie droite pour cancer. L'essai a été réalisé selon la formulation pragmatique de Schwartz. Tous les 5 groupes étaient bien appareillés à l'exception du plus petit taux de suppuration dans le groupe par anastomose mécanique (P〈0.02). Le principal résultat était le lachâge d'anastomose détecté cliniquement ou par un lavement de routine aux produits hydrosolubles au 8–10ème jour post-opératoire. Les résultats montraient que les anastomoses mécaniques étaient associées avec moins de lachage d'anastomose (2,8%) que toutes les autres techniques (8,3%). En dépit du fait que les anastomoses mécaniques sont approximativement 10 fois plus chères, nos résultats suggèrent qu'il faut réaliser des anastomoses latéro-larérales (GIA + TA) mécaniques après hémi-colectomie droite pour cancer.
    Notes: Abstract 440 patients were prospectively enrolled in a randomized, multicenter trial to compare 4 types of manual (84 interrupted end-to-end, 77 continuous end-to-side) 82 interrupted end-to-side, and 91 continuous end-to-side (polyglycolic derived suture) and 1 type of stapled (106 side-to-side with GIA + TA devices) ileocolonic anastomosis after right hemicolectomy for carcinoma. The trial was designed according to Schwartz' pragmatic formulation. All 5 groups were well-matched, except for a lower rate of intraoperative sepsis in the stapled group (P〈0.02). The main end point was anastomotic leakage detected clinically or by routine sodium diatrizoate enema on the 8–10th postoperative day. Results showed that stapled ileocolonic anastomosis was associated with less anastomotic leakages (2.8%) than all the other techniques combined (8.3%). In spite of the fact that staples are approximately ten times more expensive, our results suggest performing side-to-side (GIA + TA) mechanical anastomosis after right resection for carcinoma.
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