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  • 1
    Electronic Resource
    Electronic Resource
    Cercarial dermatitis contracted via contact with an aquarium: case report and review (2001)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 145 (2001), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Cercarial dermatitis (‘swimmer’s itch') is an itchy inflammatory response to the penetration of the skin by non-human Schistosoma parasites. It is commonly contracted while swimming or wading in lakes. We report a biology teacher who developed the dermatitis after cleaning the school aquarium in which he kept a water snail and some fish.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2133.2001.04414.x
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  • 2
    Electronic Resource
    Electronic Resource
    Pigmented pedunculated malignant melanoma. A rare variant of nodular melanoma (1995)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 133 (1995), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We report a 44-year-old man who presented with a rapidly growing, deeply pigmented, peduncu-lated tumour. The lesion was diagnosed as a pedunculated malignant melanoma, a rare variant of nodular malignant melanoma. The clinical presentation of this tumour and its histological features are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1995.tb02633.x
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  • 3
    Electronic Resource
    Electronic Resource
    Lack of association of SPINK5 polymorphisms with nonsyndromic atopic dermatitis in the population of Northern Germany (2005)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 152 (2005), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.2005.06602.x
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  • 4
    Electronic Resource
    Electronic Resource
    A multicentre, randomized, double-blind, controlled study of long-term treatment with 0·1% tacrolimus ointment in adults with moderate to severe atopic dermatitis (2005)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 152 (2005), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  Atopic dermatis (AD) is a chronic disease that often requires long-term treatment. Topical corticosteroids are the usual therapy for patients with AD, but prolonged usage can result in skin atrophy and other side-effects.Objectives  In a randomized, double-blind, comparative study, to compare the efficacy and safety of a 6-month treatment period with 0·1% tacrolimus ointment vs. a corticosteroid ointment regimen in adults with moderate to severe AD.Methods  Treatment was applied twice daily for a maximum of 6 months. Patients in the tacrolimus treatment group (n = 487) applied 0·1% tacrolimus ointment to all affected areas over the whole body. The patients treated with the corticosteroid regimen (n = 485) applied 0·1% hydrocortisone butyrate ointment to affected areas on the trunk and extremities and 1% hydrocortisone acetate ointment to affected areas on the face and neck. The study primary endpoint was the response rate, i.e. the proportion of patients with at least 60% improvement in the modified Eczema Area and Severity Index (mEASI) between baseline and month 3.Results  By month 3, more patients in the 0·1% tacrolimus group responded to treatment (72·6% vs. 52·3% in the corticosteroid group, P 〈 0·001). The patients treated with 0·1% tacrolimus also showed greater improvement in mEASI, EASI, affected body surface area and physician and patient assessments of global response. Patients applying 0·1% tacrolimus ointment experienced more skin burning (52·4% vs. 13·8% in the corticosteroid group; P 〈 0·001). In most patients, skin burning was mild to moderate in severity and decreased rapidly after the first week of treatment. There was no increase in the incidence of infections or malignancies over time in either treatment group.Conclusions  Long-term treatment with 0·1% tacrolimus ointment is significantly more efficacious than a corticosteroid ointment regimen in adults with moderate to severe AD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.2005.06592.x
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  • 5
    Electronic Resource
    Electronic Resource
    Epithelial barrier function and atopic diathesis in rosacea and perioral dermatitis (2004)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 150 (2004), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  Rosacea and perioral dermatitis (PD) are common dermatoses, the aetiology and pathogenesis of which remain speculative.Objectives  To investigate skin barrier function and features of atopy in both diseases.Methods  We studied 75 patients with rosacea and 75 with PD. Transepidermal water loss (TEWL) was measured in three regions of the face (lateral chin, perinasal cheek, side of the nose) and the patients were assessed for atopy by clinical criteria, prick tests and specific IgE against a mixture of aeroallergens (CAP SX1). The control group consisted of 125 individuals with no history of rosacea, PD or active atopic disease.Results  In patients with PD, TEWL was significantly increased (P 〈 0·001) at all measurement points in comparison with the rosacea and control groups. Significantly (P 〈 0·001) higher values were also found regarding history and clinical signs of an atopic diathesis, prick test reactivity and specific IgE against aeroallergens.Conclusions  PD is characterized by a skin barrier disorder of facial skin. It differs from rosacea in that it involves a significantly increased TEWL and features of an atopic diathesis. However, it remains disputed as to whether PD is an individual skin disease or a subtype of rosacea in atopic patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.2004.05985.x
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  • 6
    Electronic Resource
    Electronic Resource
    Cow's milk protein allergy — Results of skin-prick test with purified milk proteins (1990)
    Springer
    European journal of nutrition 29 (1990), S. 122-128 
    Details
    ISSN: 1436-6215
    Keywords: cow's milk proteinallergy ; purifiedmilkproteins ; skin-prick test ; main allergen ; Kuhmilchproteinallergie ; gereinigte Milchproteine ; Hauttest ; Hauptallergen
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Zusammenfassung Die Diagnose von Milchproteinallergien ist schwierig. Aus diesem Grunde wurden hochgereinigte Hauptproteine der Kuhmilch (α-Lactalbumin, β-Lactoglobulin A + B, αs-Casein, β-Casein, κ-Casein) unter Anwendung des Hautpricktestes für die Differentialdiagnose bei Allergikern eingesetzt. Hierbei zeigte sich, daß Milchproteine bei Erwachsenen mit unklarer Anamnese nur selten Hautreaktionen auslösten, während bei 11 von 13 Kindern mit starkem Verdacht auf Milchproteinallergie deutliche Hautreaktionen beobachtet wurden. In der vorliegenden Untersuchung waren α-Lactalbumin und β-Lactoglobulin die Hauptallergene, weil sie mit höchster Prävalenz und Intensität Hautreaktionen auslösten. Reaktionen auf α- und κ-Casein erfolgten mit deutlich geringerer Häufigkeit und Intensität. In zwei Fällen wurde eine ausschließliche Reaktion auf α-Lactalbumin beobachtet.
    Notes: Summary The diagnosis of milk-protein allergies is difficult. Therefore, the main cow's milk proteins (α-lactalbumin, β-lactoglobulin A + B, αs-casein, β-casein, κ-casein), purified to the highest available standards, were used for differential diagnosis of allergic individuals by applying skin-prick test. In the case of adults with uncertain medical history, milk proteins rarely caused skin reactions, while distinct skin reactions were observed in 11 of 13 children with strongly suspected milk-protein allergy. In the presented study α-lactalbumin and β-lactoglobulin B were the main allergens, because skin reactions to these proteins were provoked with highest prevalence and intensity. Intensity and prevalence of reactions to α- and κ-casein were significantly less. In two cases skin reactions to α-lactalbumin were observed exclusively.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02021667
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  • 7
    Electronic Resource
    Electronic Resource
    Exantheme im Kindesalter Teil I: Exantheme durch Viren (1999)
    Springer
    Monatsschrift Kinderheilkunde 147 (1999), S. 1036-1052 
    Details
    ISSN: 1433-0474
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Lernziel In der folgenden Übersicht werden exanthematische Erkrankungen der kindlichen Haut zusammenfassend dargestellt. Dabei verdienen Epidemiologie, Ätiopathogenese, Klinik, Komplikationen, Diagnostik, Therapie und Differentialdiagnosen besonderes Augenmerk. Neben der Beschreibung der einzelnen Krankheitsbilder erleichtern die Tabellen die Einordnung der Erkrankungen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001120050538
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  • 8
    Electronic Resource
    Electronic Resource
    Exantheme im Kindesalter Teil 2: Bakterien- und medikamenteninduzierte Exantheme, Exantheme nach Knochenmarktransplantation, Exantheme unklarer Ätiopathogenese (1999)
    Springer
    Monatsschrift Kinderheilkunde 147 (1999), S. 1130-1146 
    Details
    ISSN: 1433-0474
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001120050553
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  • 9
    Electronic Resource
    Electronic Resource
    Filiforme Keratose (1994)
    Springer
    Der Hautarzt 45 (1994), S. 484-488 
    Details
    ISSN: 1432-1173
    Keywords: Schlüsselwörter: Filiforme Keratosen – Etretinat ; Key words: Filiform keratoses – Etretinate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary. A 53-year-old female patient developed disseminated, filiform keratoses up to 4 mm long on the back, arms and neck and upper thorax for the first time 10 years ago. There were no associated diseases or symptoms. Treatment with etretinate was successful. After discontinuing this therapy the patient had a relapse. With this observation we bring new arguments into the discussion on filiforme keratoses.
    Notes: Zusammenfassung. Bei einer 53jährigen Patientin traten erstmals vor 10 Jahren filiforme, bis zu 4 mm lange, disseminiert stehende Keratosen am Rücken, den Oberarmen sowie im Hals-Brustbereich auf. Begleiterkrankungen ebenso wie Beschwerden fehlten. Therapeutisch erwies sich die Behandlung mit Etretinat als erfolgreich, nach Absetzen von Etretinat trat jedoch prompt ein Rezidiv auf. Mit dieser Beobachtung wird das Krankheitsbild der filiformen Keratosen erneut diskutiert.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001050050110
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  • 10
    Electronic Resource
    Electronic Resource
    ,,Blaue`` Variante eines Naevus spilus (1995)
    Springer
    Der Hautarzt 46 (1995), S. 349-351 
    Details
    ISSN: 1432-1173
    Keywords: Key words Speckled lentiginous naevus — Agminate blue naevus — Histology — Immunohistochemistry ; Schlüsselwörter Naevus spilus — Blauer Nävuszellnävus — Histologie — Immunhistochemie
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary We report on a 29-year-old female patient with an unusual pigmented lesion of the face. Clinically the lesion looked like a pigment patch of the naevus spilus type, while histological examination revealed the presence of dermal melanocytosis and multiple common blue naevi with a discrete lentiginous component in addition. The melanocytic nature of the infiltrate was ascertained by immunohistochemistry analysis using S 100 protein and HMB 45 antibodies. We interpret this lesion as agminated blue naevi in association with lentigo simplex, an unusual variant of speckled lentiginous naevus.
    Notes: Zusammenfassung Es wird über eine 29jährige Patientin mit einem ungewöhnlichen Pigmentmal des Gesichtes berichtet. Im klinischen Aspekt entsprach die Pigmentläsion einem Naevus spilus, in der histologischen Diagnostik konnte das Bestehen multipler blauer Naevi gesichert werden, daneben bestand eine gering ausgeprägte lentiginöse Komponente wie auch eine dermale Melanozytose. Immunhistochemisch zeigten die melanozytären Zellelemente eine Expression des S-100-Proteins und des Melanozyten-Markers HMB-45. Die Veränderung erweist sich damit als die ungewöhnliche Kombination einer Lentigo simplex mit aggregierten blauen Nävi und einer dermalen Melanozytose.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001050050266
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