ISSN:
1432-8798
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Examination of the intracellular and extracellular virus yields from individual FL and primary human amnion cells of uniform size, infected at a high multiplicity and incubated for specified time intervals, showed that the time of the onset of the appearance of mature infectious virus and the amount of accumulated infectious virus were variable from cell to cell. The duration of the major accumulation of mature virus by individual cells was found to be from 4 to 6 hours. The cells in the FL population, infected with Type 1 poliovirus, fell into two classes in regard to the accumulation and release of virus. The “early releasers” released some virus during the period of accumulation, yet they continued to accumulate additional virus which they subsequently released. The “late releasers”, represented by the majority of the cells, released virus at some time after accumulation had ceased. All cells in the primary human amnion cultures, infected with Coxsackie A-9 virus studied fell into the “late releasing” class.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01241308
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