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  • 1
    Electronic Resource
    Electronic Resource
    Structure and magnetic properties of RCo7−xZrx (R=Pr or Er, x=0–0.8) (1999)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 85 (1999), S. 5663-5665 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Alloys of composition RCo7−xZrx (R=Pr or Er and x=0−0.8) were synthesized and characterized in the temperature range of 10–1273 K in fields up to 5 T. As with the SmCo7−xZrx system studied earlier in our laboratory, the effects of Zr doping on the stability of the TbCu7 phase and the increase in the anisotropy field HA are also observed in the systems of PrCo7−xZrx and ErCo7−xZrx. Nearly single phase TbCu7 materials were formed in as-cast alloys when x=0.1–0.2. In the case of R=Pr, HA changes from almost planar for x=0 to uniaxial with Ha∼100 kOe for x≥0.2 at room temperature (RT). In the case of R=Er, HA for the x=0.1 composition is almost two times larger than that of the Zr-free alloys, which shows strong uniaxial anisotropy at both RT and 10 K. Spin reorientation behavior (when R=Pr) and R–M antiparallel coupling (when R=Er) were also observed. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.369833
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A Mandibular Fragment, Probably of the Saldanha Skull (1955)
    [s.l.] : Nature Publishing Group
    Nature 175 (1955), S. 364-365 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN reconstructing the Saldanha skull-cap (see Nature, 172, 791 ; 1953), a few small fragments were temporarily left out, because we did not have all the pieces necessary to complete the 'jig-saw puzzle'. Among these fragments was part of the ramus of a mandible with the coronoid process on it; but ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/175364a0
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    A Contribution to the Piltdown Problem (1927)
    [s.l.] : Nature Publishing Group
    Nature 120 (1927), S. 874-874 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SINCE the discovery of the fragments of the Piltdown skull in 1912, there has been considerable difference of opinion with regard to the manner in which the skull should be reconstructed, and as a necessary consequence of this, with regard to the extent of its cranial capacity. Estimates ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/120874a0
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  • 4
    Electronic Resource
    Electronic Resource
    The Saldanha Skull and its Associations (1953)
    [s.l.] : Nature Publishing Group
    Nature 172 (1953), S. 791-793 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE expanding story of early man is a composite one, depending for its growth and documentation on the evidence from fossil remains and stone implements. It is in the nature of things that his stone implements should have survived the passage of time to a far greater extent than his bony remains. ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/172791a0
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  • 5
    Electronic Resource
    Electronic Resource
    The homologies of the arm and leg (1927)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 35 (1927), S. 113-128 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1090350207
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  • 6
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    The Thymic Microenvironment Differentially Regulates Development and Trafficking of Invariant NKT Cell Sublineages [IMMUNE SYSTEM DEVELOPMENT] (2014)
    The American Association of Immunologists (AAI)
    Details
    Publication Date: 2014-12-06
    Description: The regulatory role of the thymic microenvironment during trafficking and differentiation of the invariant NKT (iNKT) cell lineage remains poorly understood. In this study, we show that fractalkine receptor expression marks emigrating subpopulations of the NKT1, NKT2, and NKT17 sublineages in the thymus and peripheral organs of naive mice. Moreover, NKT1 sublineage cells can be subdivided into two subsets, namely NKT1 a and NKT1 b , which exhibit distinct developmental and tissue-specific distribution profiles. More specifically, development and trafficking of the NKT1 a subset are selectively dependent upon lymphotoxin (LT)α 1 β 2 -LTβ receptor–dependent differentiation of thymic stroma, whereas the NKT1 b , NKT2, and NKT17 sublineages are not. Furthermore, we identify a potential cellular source for LTα 1 β 2 during thymic organogenesis, marked by expression of IL-7Rα, which promotes differentiation of the NKT1 a subset in a noncell-autonomous manner. Collectively, we propose a mechanism by which thymic differentiation and retention of the NKT1 sublineage are developmentally coupled to LTα 1 β 2 -LTβ receptor–dependent thymic organogenesis.
    Print ISSN: 0022-1767
    Electronic ISSN: 1550-6606
    Topics: Medicine
    Published by The American Association of Immunologists (AAI)
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  • 7
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    NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20 (2016)
    Rockefeller University Press
    Details
    Publication Date: 2016-09-20
    Description: Natural killer T (NKT) cells are innate lymphocytes that differentiate into NKT1, NKT2, and NKT17 sublineages during development. However, the signaling events that control NKT sublineage specification and differentiation remain poorly understood. Here, we demonstrate that the ubiquitin-modifying enzyme TNFAIP3/A20, an upstream regulator of T cell receptor (TCR) signaling in T cells, is an essential cell-intrinsic regulator of NKT differentiation. A20 is differentially expressed during NKT cell development, regulates NKT cell maturation, and specifically controls the differentiation and survival of NKT1 and NKT2, but not NKT17, sublineages. Remaining A20-deficient NKT1 and NKT2 thymocytes are hyperactivated in vivo and secrete elevated levels of Th1 and Th2 cytokines after TCR ligation in vitro. Defective NKT development was restored by compound deficiency of MALT1, a key downstream component of TCR signaling in T cells. These findings therefore show that negative regulation of TCR signaling during NKT development controls the differentiation and survival of NKT1 and NKT2 cells.
    Keywords: Lymphocyte Biology
    Print ISSN: 0022-1007
    Electronic ISSN: 1540-9538
    Topics: Medicine
    Published by Rockefeller University Press
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