Note: Includes bibliographical references and index

Note: Front Cover -- Gap Junctions -- Copyright Page -- Table of Contents -- Dedication -- Prologue -- Contributors -- Part I: The Connexin Protein Family -- Chapter 1. Divergent properties of different connexins expressed in Xenopus oocytes -- Introduction -- Expression of connexins in oocytes -- Different connexins - different fingerprints: an analysis of the voltage dependence of homotypic junctions -- Connexin structure and channel gating -- Unexpected properties of heterotypic junctions -- Conclusions -- Note added in proof -- Acknowledgements -- References -- Chapter 2. Identification of novel connexins by reduced-stringency hybridization and PCR amplification using degenerate primers -- Introduction -- Cloning strategies -- PCR cloning with degenerate primers -- Relationship between connexin family members -- Expression patterns of connexins -- Discussion -- Acknowledgements -- References -- Chapter 3. Affinities between connexins -- Introduction -- Channel formation -- Affinities between hemichannels -- Amino acids that determine hemichannel affinity -- Conclusions -- Acknowledgements -- References -- Chapter 4. Expression of Cx43 in rat and mouse liver -- Introduction -- Results -- Discussion -- Acknowledgements -- References -- Chapter 5. The mouse connexin gene family -- Introduction -- Summarized characterization of mouse connexins -- Discussion -- Acknowledgments -- References -- Part II: Structure -- Chapter 6. Atomic force microscopy of gap junctions -- Introduction -- Experimental methods and results -- Conclusions -- Acknowledgements -- References -- Chapter 7. Structure and design of cardiac gap-junction membrane channels -- Introduction -- Tissue distribution of gap-junction proteins: immunofluorescence microscopy -- Quaternary structure: electron microscopy and image analysis. , Tertiary structure: immunolabeling with site-specific peptide antibodies -- Secondary structure: circular dichroism spectroscopy -- Implications for the structure and function of cardiac gap-junction membrane channels -- Acknowledgments -- References -- Chapter 8. Biochemistry of gap-junction channels -- References -- Chapter 9. In-vitro assembly of lens gap junctions -- Summary -- Introduction -- Material and methods -- Results -- Conclusions -- Acknowledgements -- References -- Part III: Hemichannels -- Chapter 10. Connexins, gap-junction proteins, and ATP-induced pores in macrophages -- Introduction -- Mouse macrophages express the gap-junction protein Cx43 -- ATP-induced pores in mouse macrophages -- ATP pores and Cx43 -- Acknowledgements -- References -- Chapter 11. Connexin46 forms gap-junctional hemichannels in Xenopus oocytes -- Introduction -- Connexin46 is a gap-junctional protein -- Expression of Cx46 in Xenopus oocytes -- Regulation of Ih -- Time course of development of Ih -- Conclusions -- Acknowledgements -- References -- Chapter 12. Solitary retinal horizontal cells express hemi-gap-junction channels -- Introduction -- Reducing the extracellular Ca2+ concentration reveals a dopamine-sensitive current, Ιγ -- Ιγ is conducted by hemi-gap-junction channels -- Single-channel properties -- Conclusions -- Acknowledgements -- References -- Part IV: Biophysics -- Chapter 13. Molecular and biophysical properties of the connexins from developing chick heart -- Introduction -- Connexins of developing chick heart -- Developmental changes in regulation of junctional conductance in embryonic chick heart -- Functional expression of chick Cx43 -- Preliminary observations with chick Cx42 and -45 -- Acknowledgements -- References -- Chapter 14. Multiple channel conductance states in gap junctions -- Introduction. , Are gap-junction channels two-state devices -- Conclusions -- References -- Chapter 15. Comparison of voltage dependent properties of gap junctions in hepatocytes and in Xenopus oocytes expressing Cx32 and Cx26 -- Introduction -- Methods -- Results and discussion -- Voltage dependence of gap junctions in rat hepatocytes -- Conclusions -- References -- Chapter 16. Influence of lipophilic compounds on gap-junction channels -- Introduction -- Results and discussion -- Summary -- Acknowledgements -- References -- Chapter 17. Evidence for heterogeneous channel behavior in gap junctions -- Introduction -- Heterogeneous channel types -- Substates -- Conductance shifts -- Conclusions -- Acknowledgement -- References -- Chapter 18. Unmasking electrophysiological properties of connexins 32 and 43: transfection of communication-deficient cells with wild type and mutant connexins -- Introduction -- Methods -- Differences between Cx32 and Cx43 expressed in the same system -- Similar connexins expressed in different tissues -- Cx43 mutants where unitary conductance changes -- Effects of phosphorylation on human Cx43 channels -- Aims and possibilities -- Conclusions -- References -- Part V: Role of Gap Junctions in Various Tissues and Organisms -- Chapter 19. Plasticity of gap junctions at mixed synapses -- Introduction -- cAMP regulation of junctional transmission -- Activity-dependent changes in synaptic strength -- Discussion -- Acknowledgments -- References -- Chapter 20. Regulation of connexin32 in motor networks of mammalian neurons -- Introduction -- The localization of Cx32 in motor networks -- Androgenic regulation of Cx32 in spinal motor neurons -- Dopaminergic regulation of Cx32 in neostriatal neurons -- Acknowledgements -- References -- Chapter 21. Channel reconstitution from lens MP70 enriched preparations -- Introduction. , Preparation of MP70 enriched fractions -- Single-channel recordings from MP70-enriched preparations -- Outlook -- Acknowledgements -- References -- Chapter 22. Does MIP play a role in cell-cell communication -- Introduction -- Guilt by association -- What can MIP do -- All in the family -- Discussion -- Acknowledgements -- References -- Chapter 23. Gap-junction channel reconstitution in artificial bilayers and evidence for calmodulin binding sites in MIP26 and connexins from rat heart, liver and Xenopus embryo -- Introduction -- In vitro reconstitution of gap-junction channels -- CaM receptor sites in MIP26 and in connexins (Cx43, Cx32 and Cx38) -- Conclusions -- Acknowledgement -- References -- Chapter 24. Expression of multiple connexins by cells of the cardiovascular system and lens -- Introduction -- The connexin family of gap-junction proteins -- Multiple connexins expressed in heart -- Lens connexins -- Summary and future directions -- or multiple connexins, so what -- References -- Chapter 25. The developmental expression and organization of membrane proteins of the mammalian lens -- Introduction -- Results and discussion -- Acknowledgements -- References -- Chapter 26. Are cardiac gap junctions voltage sensitive -- Introduction -- Methods -- Results and discussion -- Acknowledgements -- References -- Chapter 27. Trypanosome infection decreases intercellular communication between cardiac myocytes -- Introduction -- Results -- Discussion and conclusions -- Acknowledgements -- References -- Chapter 28. Rat pancreatic acinar cell coupling: comparison of extent and modulation in vitro and in vivo -- Introduction -- Methods -- Secretion and coupling under resting conditions -- Secretion and coupling under stimulatory conditions -- Mechanisms controlling secretion and cell coupling -- Conclusions -- Acknowledgments -- References. , Chapter 29. Delayed change in gap-junctional cell communication in the acinus of the rat submandibular gland after secretion of saliva -- Introduction -- Rapid inhibition of dye coupling in the acinar cells of the submandibular gland by secretagogues -- Mechanism of the rapid Ach-induced inhibition of dye coupling -- Delayed inhibition of gap-junctional cell communication by ACh -- Relationship between delayed inhibition of dye coupling and salivary secretion -- Delayed inhibition of dye coupling by parasympathectomy -- Two types of inhibition of gap-junctional cell communication related to saliva secretion -- Acknowledgements -- References -- Chapter 30. Gap junctions in human corpus cavernosum vascular smooth muscle: a test of functional significance -- Introduction -- Methods -- Results -- Discussion -- Acknowledgements -- References -- Chapter 31. Role of gap junctions in mesoderm induction in Patella vulgata (Mollusca, Gastropoda): a reinvestigation -- Introduction -- Results -- Discussion -- Acknowledgements -- References -- Chapter 32. Gap-junction proteins and communication in human epidermis -- Introduction -- Junctional communication of human keratinocytes -- Connexins expressed in human epidermis -- Effects of retinoic acid on keratinocyte coupling and Cx43 expression -- Conclusions -- Acknowledgments -- References -- Chapter 33. Expression patterns of a α and β2 gap-junction gene products during rat skin and hair development -- Introduction -- Results and discussion -- Conclusions -- References -- Chapter 34. Double whole-cell patch-clamp of gap junctions in insect epidermal cell pairs: single channel conductance, voltage dependence, and spontaneous uncoupling -- Introduction -- Materials and methods -- Results and discussion -- Conclusions -- Acknowledgements -- References. , Chapter 35. Insect cell pairs: electrical properties of intercellular junctions.

Note: Front Cover -- Hydrodynamics and Sedimentation in Wave-Dominated Coastal Environments -- Copyright Page -- Contents -- Preface -- Chapter 1. Waves, long waves and nearshore morphology -- Chapter 2. Spatial and temporal variations in spectra of storm waves across a barred nearshore -- Chapter 3. Waves, currents, sediment flux and morphological response in a barred Nearshore System -- Chapter 4. Landward migration of inner bars -- Chapter 5. Sediment flux and equilibrium slopes in a barred nearshore -- Chapter 6. Sediment transport and morphology at the surf zone of Presque Isle, Lake Erie, Pennsylvania -- Chapter 7. Sedimentology and morphodynamics of a microtidal beach, Pendine Sands, SW Wales -- Chapter 8. High-frequency sediment-level oscillations in the swash zone -- Chapter 9. Wave-formed structures and paleoenvironmental reconstruction -- Chapter 10. Boundary roughness and bedforms in the surf zone -- Chapter 11. Tidal-cycle changes in oscillation ripples on the inner part of an estuarine sand flat -- Chapter 12. Bedforms and depositional sedimentary structures of a barred nearshore system, eastern Long Island, New York -- Chapter 13. Beach and nearshore facies: southeast Australia -- Chapter 14. Structures in deposits from beach recovery, after erosion by swell waves around the southwestern coast of Aruba (Netherlands Antilles) -- Chapter 15. What is a wave-dominated coast? -- Chapter 16. Shoreface morphodynamics on wave-dominated coasts -- Chapter 17. Control of barrier island shape by inlet sediment bypassing: East Frisian Islands, West Germany -- Chapter 18. Coarse clastic barrier beaches: A discussion of the distinctive dynamic and morphosedimentary characteristics -- Chapter 19. Shoreface translation and the Holocene stratigraphic record: Examples from Nova Scotia, the Mississippi Delta and eastern Australia. , Chapter 20. Holocene sedimentation of a wave-dominated barrier-island shoreline : Cape Lookout, North Carolina -- Chapter 21. Reconstruction of paleo-wave conditions during the Late Pleistocene from marine terrace deposits, Monterey Bay, California -- Chapter 22. Reconstruction of ancient sea conditions with an example from the Swiss Molasse.