Note: Amino Acids, Peptides, and Proteins -- Contents -- Chapter 1 Amino Acids -- 1 Introduction -- 2 Textbooks and Reviews -- 3 Naturally Occurring Amino Acids -- Isolation of Amino Acids from Natural Sources -- Occurrence of Known Amino Acids -- New Naturally Occurring Amino Acids -- New Amino Acids from Hydrolysates -- 4 Chemical Synthesis and Resolution of Amino Acids -- General Methods of Synthesis of α-Amino Acids -- Asymmetric Synthesis of α-Amino Acids -- Synthesis of Protein Amino Acids and Other Naturally Occurring α-Amino Acids -- α-Alkyl Analogues of Protein Amino Acids -- Synthesis of C-Alkyl and Substituted C-Alkyl α-Amino Acids, and Cyclic Analogues -- Models for Prebiotic Synthesis of Amino Acids -- α-Alkoxy α-Amino Acids -- α-(Halogenoalkyl) α-Amino Acids -- α-(Hydroxyalkyl) α-Amino Acids -- α-Amino Acids with Aminoalkyl Side-chains -- α-Amino Acids with Unsaturated Side-chains -- α-Amino Acids with Aromatic and Heteroaromatic Side-chains -- N-Substituted α-Amino Acids -- Sulphur Containing α-Amino Acids -- Phosphorus Containing α-Amino Acids -- Synthesis of Labelled Amino Acids -- Synthesis of β-Amino Acids, and Higher Homologous Amino Acids -- Resolution of DL-α-Amino Acids -- 5 Physico-chemical Studies of Amino Acids -- X-Ray Crystal Structure Analysis of Amino Acids -- Nuclear Magnetic Resonance Spectrometry -- Optical Rotatory Dispersion and Circular Dichroism -- Mass Spectrometry of α-Amino Acids and Related Gas Phase Studies -- Other Spectrometric Studies of Amino Acids -- Other Physico-Chemical Studies -- Molecular Orbital Calculations for α-Amino Acids -- 6 Chemical Studies of Amino Acids -- Racemization -- General Reactions of Amino Acids -- Specific Reactions of Amino Acids -- Effects of Electromagnetic Radiation on Amino Acids -- 7 Analytical Methods -- General -- Gas-Liquid Chromatography -- Thin-layer Chromatography. , Ion-exchange Chromatography -- High Performance Liquid Chromatography -- Other Analytical Methods -- Determination of Specific Amino Acids -- References -- Chapter 2 Peptide Synthesis -- 1 Introduction -- 2 Methods -- α-Amino-group Protection -- Carboxyl-group Protection -- Side-chain Protection -- General Deprotection -- Peptide Bond Formation -- Disulfide Bond Formation -- Solid-phase Peptide Synthesis -- Enzyme-mediated Synthesis and Semi-synthesis -- Miscellaneous Reactions Related to Peptide Synthesis -- 3 Selected Examples of Peptide Syntheses -- 4 Appendix. A List of Syntheses Reported in 1992 -- Natural Peptides, Proteins, and Partial Sequences -- Sequential Oligo- and Poly-peptides -- Enzyme Substrates and Inhibitors -- Conformation of Synthetic Peptides -- Glycopeptides -- Phosphopeptides and Related Compounds -- Immunogenic Peptides -- Miscellaneous Peptides -- 5 Purification Methods -- References -- Chapter 3 Analogue and Conformational Studies on Peptide Hormones and Other Biologically Active Peptides -- 1 Introduction -- 2 Peptide-backbone Modifications -- ψ[CSNH]-Thioamide Analogues -- ψ[NHCO]-Retro-Inverso Analogues -- ψ[CH2NH]-Amino Methylene Analogues -- ψ[CH = CH]- and ψ [CH2 = CH2]-Ethylenic and Carba Analogues -- ψ[COCH2] and ψ [CH(OH)CH2]-Keto-methylene and Hydroxymethylene Analogues -- Phosphono-Peptides -- ψ[SO2NH] Analogues -- C-Terminal Modifications -- Miscellaneous Modifications -- α,α-Dialkylated Glycine Analogues -- 3 Conformationally Restricted Cyclic and Bridged Analogues -- Rings and Bridges formed via Amide Bonds -- Bridges formed by Disulphide Bonds -- Miscellaneous Bridges and β-Turn Mimetics -- 4 Dehydroamino Acid Analogues -- 5 Enzyme Inhibitors -- Angiotensin Converting Enzyme (ACE) Inhibitors -- Renin Inhibitors -- HIV-1 Protease Inhibitors -- Inhibitors of Other Proteases. , 6 Side-chain Interactions Studied by Residue Substitution or Deletion and Similar Modifications -- Peptides with 'Opioid Characteristics' -- Cholecystokinin Analogues -- Angiotensin and Analogues -- Oxytocin and Vasopressin Analogues -- Luteinising Hormone-releasing Hormone (LHRH) Analogues -- Tachykinin Analogues -- Somatostatin Analogues -- Bradykinin Analogues -- Miscellaneous Examples -- 7 Conformational Information Derived from Physical Methods -- References -- Chapter 4 Cyclic, Modified, and Conjugated Peptides -- 1 Introduction -- 2 Cyclic Peptides -- General Considerations -- Naturally Occurring Dioxopiperazines (Cyclic Dipeptides) -- Other Dioxopiperazines -- Cyclotripeptides and Cyclotetrapeptides -- Cyclopentapeptides -- Cyclohexapeptides -- Cycloheptapeptides and Cyclo-octapeptides -- Cyclononapeptides -- Cyclodecapeptides -- Higher Cyclic Peptides -- Peptides containing Thiazole Type Rings -- Cyclodepsipeptides -- Cyclic peptides containing Other Non-protein Ring Components -- 3 Modified and Conjugated Peptides -- Phosphopeptides -- Glycopeptide Antibiotics -- Other Glycopeptides -- Lipopep tides -- 4 Miscellaneous Examples -- References -- Chapter 5 Current Trends in Protein Research -- 1 Introduction -- 2 Protein Sequencing -- Mass Measurements of Proteins -- 3 Protein Sequence and Structure -- Structural Motifs -- Loop Regions in Proteins -- Protein Modules -- 4 Protein Folding -- 5 Protein Stability -- 6 Proteins that Bind Nucleic Acid -- Transcription Factors -- DNA Repair Enzymes -- Restriction Enzymes -- DNA Polymerases -- Aminoacyl tRNA Synthetases -- 7 Other Proteins of Special Interest -- Antibodies -- Lipases -- Cholinesterases -- Other X-Ray Protein Structures -- 8 Metal Containing Proteins -- Zinc Proteins -- Calcium Proteins -- Tungsten Proteins -- Iron Proteins -- Copper Proteins -- 9 Catalytic Mechanism. , Substrate Specificity -- 10 Protein-Protein Interactions -- References -- Chapter 6 Metal Complexes of Amino Acids and Peptides -- 1 Introduction -- 2 Amino Acid Complexes -- Crystal and Molecular Structures -- Synthesis -- Solution Studies: Structures and Reactions -- Formation Constants -- Catalysis -- 3 Peptide Complexes -- Synthesis, Crystal Structures -- Reactivity -- Solution Chemistry -- Miscellaneous -- References.

Note: Cover -- Prelims -- Preface -- Contents -- Abbreviations -- 1 Amino Acids -- 1 Introduction -- 2 Textbooks and Reviews -- 3 Naturally Occurring Amino Acids -- 3.1 Isolation of Amino Acids from Natural Sources -- 3.2 Occurrence of Known Amino Acids -- 3.3 New Naturally Occurring Amino Acids -- 3.4 New Amino Acids from Hydrolysates -- 4 Chemical Synthesis and Resolution of Amino Acids -- 4.1 General Methods for the Synthesis of a-Amino Acids -- 4.2 Asymmetric Synthesis of a-Amino Acids -- 4.3 Synthesis of Protein Amino Acids and Other Naturally Occurring a-AminoAcids -- 4.4 Synthesis of a-Alkyl Analogues of Protein Amino Acids -- 4.5 Synthesis of a-Amino Acids Carrying Alkyl Side-chains, and CyclicAnalogues -- 4.6 Models for Prebiotic Synthesis of Amino Acids -- 4.7 Synthesis of a-Alkoxy-a-Amioo Acids and Analogous a-Heteroatomsubstituteda-Amino Acids -- 4.8 Synthesis of a-Halogenoalkyl a-Amino Acids -- 4.9 Synthesis of a-(a-Hydroxyalkyl) a-Amino Acids -- 4.10 Synthesis of a-Amino Acids with Unsaturated Aliphatic Side-chains -- 4.11 Synthesis of a-Amino Acids with Aromatic or Heteroaromatic Groupings inSide-chains -- 4.12 Synthesis of a-Aminoalkyl a-Amino Acids -- 4.13 Synthesis of a-Amino Acids Carrying Sulfur- or Seleniurn-containingSidechains -- 4.14 Synthesis of a-Phosphonoalkyl a-Amino Acids and a-Amino AcidsCarrying Other Phosphorus Functional Groups in Sidechains -- 4.15 Synthesis of Isotopically Labelled a-Amino Acids -- 4.16 Synthesis of p-Amino Acids and Higher Homologous Amino Acids -- 4.17 Resolution of DL-a-Amino Acids, and Assignments of AbsoluteConfiguration to Enantiomers of a-Amino Acids -- 5 Physico-chemical Studies of Amino Acids -- 5.1 X-Ray Crystal Structure Analysis of Amino Acids and Their Derivatives -- 5.2 Nuclear Magnetic Resonance Spectroscopy -- 5.3 Optical Rotatory Dispersion and Circular Dichroism. , 5.4 Mass Spectrometry -- 5.5 Other Spectrometric Studies of Amino Acids -- 5.6 Other Physico-chemical Studies of Amino Acids -- 5.7 Molecular Orbital Calculations for a-Amino Acids -- 6 Chemical Studies of Amino Acids -- 6.1 Racemization -- 6.2 General Reactions of Amino Acids -- 6.3 Specific Reactions of Amino Acids. -- 6.4 Effects of Electromagnetic Radiation on Amino Acids -- 7 Analytical Methods -- 7.1 Introduction -- 7.2 Gas-Liquid Chromatography -- 7.3 Thin-layer Chromatography -- 7.4 High Performance Liquid Chromatography -- 7.5 Fluorimetric Analysis -- 7.6 Other Analytical Methods -- 7.7 Assays for Specific Amino Acids -- References -- 2 Peptide Synthesis -- 1 Introduction -- 2 Methods -- 2.1 Amino-group Protection -- 2.2 Carboxyl-group Protection -- 2.3 Side-chain Protection -- 2.4 General Deprotection -- 2.5 Peptide Bond Formation -- 2.6 Disulfide Bond Formation -- 2.7 Solid Phase Peptide Synthesis -- 2.8 Enzyme-mediated Synthesis and Semisynthesis -- 3 Selected Examples of Peptide Syntheses -- 4 Appendix: A List of Syntheses Reported in 1993 -- 4.1 Natural Peptides, Proteins and Partial Sequences -- 4.2 Sequential Oligo- and Poly-peptides -- 4.3 Enzyme Substrates and Inhibitors -- 4.4 Conformation of Synthetic Peptides -- 4.5 Glycopeptides -- 4.6 Phosphopeptides and Related Compounds -- 4.7 Immunogenic Peptides -- 4.8 Miscellaneous Peptides -- 5 Purification Methods -- References -- 3 Analogue and Conformational Studies on Peptide Hormones and Other Biologically Active Peptides -- 1 Introduction -- 2 Peptidebackbone Modifications -- 2.1 [CSNHj-Thioamide Analogues -- 2.2 [NHCO]-Retro-inverso Analogues -- 2.3 [CH2NHj-Amino Methylene Analogues -- 2.4 [CH = m- and [CH2CH2]- Ethylenic and Carba Analogues -- 2.5 Phosphono-peptides -- 2.6 [SO2NH] Analogues -- 2.7 Miscellaneous Modifications -- 2.8 a,a-Dialkylated Glycine Analogues. , 3 Conformationally Restricted Cyclic and Bridged Analogues -- 3.1 Rings and Bridges formed via Amide Bonds -- 3.2 Bridges formed by Disulfide Bonds -- 3.3 Miscellaneous Bridges and PTurn Mimetics -- 4 Dehydroamino Acid Analogues -- 5 Enzyme Inhibitors -- 5.1 Angiotensin Converting Enzyme (ACE) Inhibitors -- 5.2 Statine and Hydroxyethylene-type Dipeptide Isosteres -- 5.3 Renin Inhibitors -- 5.4 HIV-1 Protease Inhibitors -- 5.5 Inhibitors of Other Proteases -- 6 Side Chain Interactions Studied by Residue Substitution or Deletion and Similar Modifications -- 6.1 Peptides with 'Opioid Characteristics' -- 6.2 Cholecystokinin Analogues -- 6.3 Angiotensin Analogues -- 6.4 Oxytocin and Vasopressin Analogues -- 6.5 Luteinising Hormone-releasing Hormone (LHRH) Analogues -- 6.6 Tachykinin Analogues -- 6.7 Somatostatin Analogues -- 6.8 Bradykinin Analogues -- 6.9 Miscellaneous Examples -- References -- 4 Cyclic, Modified and Conjugated Peptides -- 1 Introduction -- 2 Cyclic Peptides -- 2.1 General Considerations -- 2.2 Naturally Occurring Dioxopiperazines (Cyclic Dipeptides) -- 2.3 Other Dioxopiperazines -- 2.4 Cyclotripeptides and Cyclotetrapeptides -- 2.5 Cyclopentapeptides -- 2.6 Cyclohexapeptides -- 2.7 Cycloheptapeptides and Cyclooctapeptides -- 2.8 Cyclodecapeptides -- 2.9 Higher Cyclic Peptides -- 2.10 Peptides Containing Thiazole Type Rings -- 2.11 Cyclodepsipeptides -- 2.12 Cyclic Peptides Containing 'Other' Non-protein Ring Components -- 3 Modified and Conjugated Peptides -- 3.1 Phosphopeptides -- 3.2 Glycopeptide Antibiotics -- 3.3 Glycopeptides -- 3.4 Lipopeptides -- 3.5 Oligonucleotide Peptide Conjugate -- References -- 5 Current Trends in Protein Research -- 1 Introduction -- 2 Water and Proteins -- 3 Protein Folds -- 4 New Protein Folds -- 5 Protein Folding and Protein Stability -- 6 New Protein Structures -- 6.1 Elongation Factors. , 6.2 Protein-Nucleic Acid Complexes -- 6.3 Receptor Protein Complex -- 6.4 Visual Protein -- 6.5 Muscle Proteins -- 6.6 Kinases -- 6.7 Proteases -- 6.8 Lipases -- 6.9 b-Lactamases -- 6.10 Other Enzymes -- 6.11 Enzymes Acting on Carbohydrates -- 6.12 Parasitic Enzymes -- 6.13 Immunoglobulins -- 6.14 ChaperonePeptide Complex -- 7 Protein Engineering -- 7.1 Antibody Engineering -- 8 Summary -- References -- 6 b-Lactam Chemistry -- 1 Introduction -- 2 New Natural Products -- 3 Biosynthesis -- 3.1 Penicillin and Cephalosporin Biosynthesis -- 3.2 Clavam Biosynthesis -- 3.3 Carbapenem Biosynthesis -- 3.4 Tabtoxin Biosynthesis -- 4 Penicillins and Cephalosporins -- 5 Clavulanic Acid, Oxapenams and Oxapenems -- 6 Penems -- 7 Carbapenems, Carbapenams, Carbacephems and Related Systems -- 7.1 Carbapenems and Carbapenams -- 7.2 Carbacephems -- 8 Azetidin-2-ones -- 8.1 Reactions in which One Bond is Formed -- 8.2 Reactions in which Two Bonds are Formed -- 8.2.1 [3 + 11] Additions -- 8.2.2 [2 + 2] Additions -- 8.3 Chemistry of Azetidin-2-ones -- 8.4 Further Uses of Azetidin-2-0nes -- 9 Major Structural Variants -- 10 Mechanistic Studies, Mode of Action, Degradation and New Applications -- Appendix -- Penicillins and Cephalosporins -- Penems -- Clavulanic Acid, Oxapenams and Oxapenems -- Carbapenems, Carbapenams, Carbacephems and Related Systems -- Aze tidin-2-ones -- Major Structural Variations -- Mechanistic Studies, Mode of Action, Degradation and New Applications -- References.

Note: Amino Acids, Peptides and Proteins -- Contents -- Chapter 1 Amino Acids -- 1 Introduction -- 2 Textbooks and Reviews -- 3 Naturally Occurring Amino Acids -- 3.1 Isolation of Amino Acids from Natural Sources -- 3.2 Occurrence of Known Amino Acids -- 3.3 New Naturally Occurring Amino Acids -- 3.4 New Amino Acids from Hydrolysates -- 4 Chemical Synthesis and Resolution of Amino Acids -- 4.1 General Methods for the Synthesis of α-Amino Acids -- 4.2 Asymmetric Synthesis of α-Amino Acids -- 4.3 Synthesis of Protein Amino Acids and Other Naturally Occurring α-Amino Acids -- 4.4 Synthesis of α-Alkyl Analogues of Protein Amino Acids -- 4.5 Synthesis of α-Amino Acids Carrying Alkyl Side-Chains, and Cyclic Analogues -- 4.6 Models for Prebiotic Synthesis of Amino Acids -- 4.7 Synthesis of α-Alkoxy α-Amino Acids and Analogous α-Heteroatom-substituted α-Amino Acids -- 4.8 Synthesis of α-(ω-Halogeno-alkyl) α-Amino Acids -- 4.9 Synthesis of α-(ω-Hydroxyalkyl) α-Amino Acids -- 4.10 Synthesis of α-(ω-Amino-alkyl) α-Amino Acid -- 4.11 Synthesis of α-Amino Acids Carrying Unsaturated Aliphatic Side-Chains -- 4.12 Synthesis of α-Amino Acids with Aromatic or Heteroaromatic Groupings in Side-Chains -- 4.13 Synthesis of α-Amino Acids Carrying Sulfur- or Selenium-containing Side-Chains -- 4.14 Synthesis of α-Amino Acids Carrying Phosphorus Functional Groups in Side-Chains -- 4.15 Synthesis of Isotopically-Labelled Amino Acids -- 4.16 Synthesis of β-Amino Acids and Higher Homologous Amino Acids -- 4.17 Resolution of DL-Amino Acids -- 5 Physico-Chemical Studies of Amino Acids -- 5.1 X-Ray Crystal Structure Analysis of Amino Acids and Their Derivatives -- 5.2 Nuclear Magnetic Resonance Spectrometry -- 5.3 Optical Rotatory Dispersion and Circular Dichroism -- 5.4 Mass Spectrometry -- 5.5 Other Spectroscopic Studies of Amino Acids. , 5.6 Other Physico-chemical Studies of Amino Acids -- 5.7 Molecular Orbital Calculations for Amino Acids -- 6 Chemical Studies of Amino Acids -- 6.1 Racemization -- 6.2 General Reactions of Amino Acids -- 6.3 Specific Reactions of Amino Acids -- 6.4 Effects of Electromagnetic Radiation on Amino Acids -- 7 Analytical Methods -- 7.1 Introduction -- 7.2 Gas-Liquid Chromatography -- 7.3 Thin-Layer Chromatography -- 7.4 High Performance Liquid Chromatography -- 7.5 Fluorimetric Analysis -- 7.6 Other Analytical Methods -- 7.7 Assays for Specific Amino Acids -- References -- Chapter 2 Peptide Synthesis -- 1 Introduction -- 2 Methods -- 2.1 α-Amino-group Protection -- 2.2 Carboxyl-group Protection -- 2.3 Side-chain Protection -- 2.4 Disulfide Bond Formation -- 2.5 Peptide Bond Formation -- 2.6 Solid-phase Peptide Synthesis -- 2.7 Enzyme-mediated Synthesis and Semi-synthesis -- 2.8 Miscellaneous Reactions Related to Peptide Synthesis -- 3 Appendix: A List of Syntheses Reported Mainly in 1994 -- 3.1 Natural Peptides, Proteins, and Partial Sequences -- 3.2 Sequential Oligo- and Poly-peptides -- 3.3 Enzyme Substrates and Inhibitors -- 3.4 Conformation of Synthetic Peptides -- 3.5 Glycopeptides -- 3.6 Phosphopeptides and Related Compounds -- 3.7 Immunogenic Peptides -- 3.8 Nucleopeptides -- 3.9 Miscellaneous Peptides -- 3.10 Purification Methods -- References -- Chapter 3 Analogue and Conformational Studies on Peptide Hormones and Other Biologically Active Peptides -- 1 Introduction -- 2 Peptide-backbone Modifications -- 2.1 ψ[NHCO]-Retro-inverso Analogues -- 2.2 ψ[CH2NH]-Amino Methylene and ψ[CH20]-Ether Analogues -- 2.3 ψ[CH = CH] Isosteres and Related Analogues -- 2.4 Phosphorus Containing Peptide Bond Isosteres -- 2.5 Sulfur Containing Peptide Bond Isosteres -- 2.6 Ketone Containing Isosteres -- 2.7 Hydrazine, Hydrazone and Related Isosteres. , 2.8 α,α-Dialkylated Glycine Analogues -- 2.9 Dehydroamino Acid Analogues -- 2.10 Miscellaneous Modifications -- 3 Conformationally Restricted Cyclic and Bridged Analogues -- 3.1 Rings and Bridges Formed via Amide Bonds -- 3.2 Bridges Formed by Disulfide Bonds -- 3.3 Helices and Helix Inducers -- 3.4 β-Turn Mimetics Miscellaneous Bridges -- 4 Amino Acids with Modified Side-chains -- 5 Enzyme Inhibitors -- 5.1 Renin Inhibitors -- 5.2 HIV-1 Protease Inhibitors -- 5.3 Inhibitors or Other Protease Enzymes -- 5.3.1 Serine Protease Inhibitors -- 5.3.2 Cysteine Pro tease Inhibitors -- 5.3.3 Metalloprotease Inhibitors -- 5.4 RGD Containing Peptides and Analogues -- 5.5 Miscellaneous Enzyme Inhibitors -- 6 Side Chain Interactions Studied by Residue Substitution or Deletion and Similar Modifications -- 6.1 Peptides with 'Opioid Characteristics' -- 6.2 Cholecystokinin Analogues -- 6.3 Angiotensin Analogues -- 6.4 Oxytocin and Vasopressin Analogues -- 6.5 Thrombin Binding Peptides -- 6.6 Tachykinin Analogues -- 6.7 Somatostatin Analogues -- 6.8 Bradykinin Analogues -- 6.9 Miscellaneous Examples -- References -- Chapter 4 Cyclic, Modified and Conjugated Peptides -- 1 Introduction -- 2 Cyclic Peptides -- 2.1 General Considerations -- 2.2 Dioxopiperazines (Cyclic Dipeptides) -- 2.3 Cyclotetrapeptides -- 2.4 Cyclopentapep tides -- 2.5 Cyclohexapeptides -- 2.6 Cycloheptapeptides and Cyclooctapeptides -- 2.7 Higher Cyclic Peptides -- 2.8 Peptides Containing Thiazole/Oxazole Rings -- 2.9 Cyclodepsipeptides -- 2.10 Cyclic Peptides Containing 'Other' Non-Protein Ring Components -- 3 Modified and Conjugated Peptides -- 3.l Phosphopeptides -- 3.2 Glycopeptide Antibiotics -- 3.3 Glycopeptides -- 3.4 Lipopeptides -- 3.5 Nucleoside-Oligonucleotide Conjugates -- 3.6 Miscellaneous Conjugates -- References -- Chapter 5 Metal Complexes of Amino Acids and Peptides -- 1 Introduction. , 2 Amino Acid Complexes -- 2.1 Crystal and Molecular Structures -- 2.2 Synthesis -- 2.3 Reactions/Structures in Solution -- 2.4 Formation Constants -- 3 Peptide Complexes -- 3.1 Synthesis, Structure and Reactivity -- 3.2 Formation Constants, Species in Solution -- References -- Chapter 6 Current Trends in Protein Research -- 1 Introduction -- 2 Protein Folding -- 2.1 Theoretical Approaches -- 2.2 Practical Approaches -- 3 Protein Motifs -- 3.1 pH Domain -- 3.2 Cysteine Knots -- 3.3 Leucine-rich Sequences -- 4 Metal Containing Proteins -- 4.1 Zinc Containing Proteins -- 4.1.1 Zinc Metalloproteinases -- 4.2 Iron Containing Proteins -- 4.2.1 Haem Protein Cytochrome f -- 4.2.2 Cytochrome P450 -- 4.2.3 Haem Peroxidases -- 4.2.4 Flavocytochrome c Sulfide Dehydrogenase -- 4.3 Dinuclear Iron Centre Proteins -- 5 Protein-Nucleic Acid Interactions -- 5.1 Methyltransferases -- 5.2 Restriction Endonucleases -- 5.3 E. coli Ada Protein -- 5.4 DNA and RNA Polymerases -- 5.5 DNA Topoisomerases -- 5.6 DNA Gyrase -- 6 Nucleic Acid Related Proteins -- 6.1 GTPases -- 6.2 ATPase -- 6.3 Nucleotide Synthesis Enzymes -- 6.3.1 Glutamine S-Phosphoribosyl 1-Pyrophosphate Aminotransferase -- 6.3.2 Ribonucleotide Reductase -- 6.3.3 Thymidylate Synthase -- 6.3.4 Phosphoribosyltransferase Enzymes -- 6.4 Ribosomal Proteins -- 7 Lipases -- 7.1 Lipid-Transfer Protein -- 8 Receptor Structure -- 8.1 Receptor/Cytokine Structures -- 8.2 Cell Adhesion Molecules -- 8.3 Glucose/Galactose Receptor -- 8.4 Aspartate Receptor -- 9 Protein Phosphatases -- 10 Other Protein Structures -- 10.1 Acetyl-CoA Carboxylase -- 10.2 D-Alanine: D-Alanine Ligase -- 10.3 Catechol O-Methyl Transferase -- 10.4 Cellobiohydrolase I -- 10.5 Dethiobiotin Synthetase -- 10.6 Farnesyl Diphosphate Synthase -- 10.7 β-Galactosidase -- 10.8 Haemoglutinin -- 10.9 Hevamine -- 10.10 Inositol Polyphosphate 1-Phosphatase. , 10.11 Interleukin- 1β Converting Enzyme -- 10.12 Glucose-6-phosphate Dehydrogenase -- 10.13 Citrate Synthase -- 11 Summary -- References.

Note: Amino Acids, Peptides and Proteins -- CONTENTS -- Preface -- Amino acids -- Introduction -- Naturally occuring amino acids -- Chemical synthesis and resolution of amino acids -- Physical and stereochemical studies of amino acids -- Chemical studies of amino acids -- Analytical methods -- Peptide synthesis -- Introduction -- Methods -- Appendix: A list of syntheses in 2003-2004 -- Analogue and conformational studies on peptides, hormones and other biologically active peptides -- Introduction -- Peptide backbone modifications and peptide mimetics -- Cyclic peptides -- Biologically active peptides -- Enzyme inhibitors -- Phage library leads -- Protein-protein interaction inhibitors: SH2 and SH3 domain ligands -- Cyclic, modified and conjugated peptides -- Introduction -- Cyclic peptides -- Modified and conjugated peptides -- Miscellaneous structures -- Metal complexes of amino acids and peptides -- Introduction -- Amino acid complexes -- Peptide complexes.