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  • 1
    Keywords: Entrepreneurship. ; Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (333 pages)
    Edition: 1st ed.
    ISBN: 9789811966644
    Series Statement: Microorganisms for Sustainability Series ; v.42
    DDC: 660.62
    Language: English
    Note: Intro -- Foreword -- Preface -- Contents -- Series Editor, Editors and Contributors -- Chapter 1: Microbiology-Based Entrepreneurship -- 1.1 Introduction -- 1.2 Microbiological Entrepreneurship -- 1.3 Microbiology´s Scope and Importance -- 1.4 Diagnostics -- 1.5 Biosafety -- 1.6 Hybrid Career Paths -- 1.7 Microbiology for Self-Employment and Self-Productivity -- 1.8 Conclusion -- References -- Chapter 2: Mass Multiplication, Production Cost Analysis and Marketing of Protease -- 2.1 Introduction -- 2.2 Mass Microbial Protease Production Technology -- 2.2.1 Microorganisms and Source -- 2.2.2 Bioprocesses for Protease Production -- 2.2.3 Solid-State Fermentation (SSF) -- 2.2.4 Submerged Fermentation -- 2.3 Analysis of the Protease Production Cost -- 2.4 Application of Protease -- 2.5 Detergent Industry -- 2.6 Food Industry -- 2.7 Leather Industry -- 2.8 Medical Field -- 2.9 Chemical Industry -- 2.10 Miscellaneous Applications -- 2.11 Market Trend of Protease -- 2.12 Conclusion -- References -- Chapter 3: Mass Multiplication, Production Cost Analysis and Marketing of Xylanase -- 3.1 Introduction -- 3.2 Source of Xylanase Production -- 3.3 Influencing Factors on Xylanase Production -- 3.4 Bacterial Xylanase Production Using SmF -- 3.5 Fungal Xylanase Production Using SSF -- 3.6 Analysis of the Xylanase Production Cost -- 3.7 Application and Market Trend of Xylanase -- 3.8 Conclusion -- References -- Chapter 4: Mass Multiplication, Production Cost Analysis, and Marketing of Cellulase -- 4.1 Introduction -- 4.2 Cellulase: Classification and Mode of Action -- 4.3 Source of Cellulase Production -- 4.4 Mass Production of Cellulase -- 4.4.1 Submerged Fermentation (SmF) -- 4.4.2 Solid-State Fermentation (SSF) -- 4.4.3 Fermentation Conditions -- 4.5 Analysis of the Cellulase Production Cost -- 4.6 Applications -- 4.6.1 Paper and Pulp Industry. , 4.6.2 Textile Industry -- 4.6.3 Laundry and Detergents -- 4.6.4 Food and Feed Industry -- 4.6.5 Agriculture Sector -- 4.6.6 Medical Sector -- 4.6.7 Biofuel -- 4.7 Market Trend of Cellulase -- 4.8 Conclusion -- References -- Chapter 5: Mass Multiplication, Production Cost Analysis and Marketing of Pectinase -- 5.1 Introduction -- 5.2 Pectinases -- 5.3 Classification of Pectinases -- 5.3.1 Protopectinase -- 5.3.2 Pectin Esterase (PE, De-esterase) -- 5.3.3 Depolymerising Enzyme -- 5.4 Pectin -- 5.5 Sources of Pectinases -- 5.5.1 Bacteria -- 5.5.2 Fungus -- 5.6 Insect -- 5.7 Strategies for Mass Cultivation to Enhance the Production -- 5.8 Fermentation Strategies -- 5.9 Immobilisation Strategies -- 5.10 Genetic Modification Strategies -- 5.11 Microbial Pectinase for Large-Scale Production -- 5.12 Cost Analysis Factors in Pectinase Production -- 5.12.1 Usage of Alternative Substrates -- 5.12.2 Agro-industrial Waste -- 5.13 Fruit and Vegetable Waste -- 5.14 Algal Biomass -- 5.15 Application and Market Demand -- 5.16 Conclusion -- References -- Chapter 6: Production, Cost Analysis, and Marketing of Citric Acid -- 6.1 Introduction -- 6.2 Uses -- 6.3 Commercial Strain -- 6.4 Fermentation -- 6.5 Submerged Fermentation -- 6.6 Surface Fermentation -- 6.7 Liquid Surface Fermentation -- 6.8 Solid Surface Fermentation -- 6.9 Fermentation Media -- 6.9.1 Carbon Source -- 6.9.2 Nitrogen Source -- 6.9.3 Phosphorus Source -- 6.10 Trace Elements -- 6.11 pH -- 6.12 Aeration -- 6.13 Temperature -- 6.14 Recovery and Extraction -- 6.15 Cost Analysis of Citric Acid Production -- 6.16 Marketing of Citric Acid -- 6.17 Conclusion -- References -- Chapter 7: Production, Cost Analysis and Marketing of Lactic Acid -- 7.1 Introduction -- 7.2 The Fermentation Processes -- 7.3 Microorganisms Used for the Production of Lactic Acid -- 7.4 Raw Material Used -- 7.5 Downstream Process. , 7.5.1 Clarification -- 7.5.2 Purification and Concentration -- 7.5.3 Packaging -- 7.5.4 Downtime Management -- 7.6 Cost Analysis -- 7.7 Safety and Administrative Issues During Microbial Fermentation -- 7.8 Uses of Lactic Acid -- 7.9 Conclusion -- References -- Chapter 8: Production, Cost Analysis, and Marketing of Acetic Acid (Vinegar) -- 8.1 Introduction -- 8.1.1 Vinegar -- 8.1.2 Application of Vinegar -- 8.1.3 Factors Affecting the Production of Vinegar -- 8.1.4 Methods -- 8.1.4.1 The Orleans Method -- 8.1.4.2 The Generator Method -- 8.1.4.3 Submerged Fermentation -- 8.2 Technological Details -- 8.3 Vinegar Production Process -- 8.3.1 Raw Materials Preparation -- 8.3.2 Preparation of Starter Culture/Inoculum Media -- 8.3.2.1 Maintenance of Master/Mother Culture -- 8.3.2.2 Preparation of Starter Culture -- 8.3.3 Mass Multiplication -- 8.3.4 Alcoholic Fermentation -- 8.3.5 Acetic Acid Fermentation -- 8.3.5.1 Maturation/Aging -- 8.3.5.2 Ultrafiltration and Pasteurization -- 8.3.6 Bottling and Packaging -- 8.3.7 Marketing -- 8.4 Project Details -- 8.5 Financial Aspects -- 8.5.1 Fixed Capital (Table 8.6) -- 8.5.2 Working Capital -- 8.5.2.1 Recurring Expenses per Annum (Table 8.11) -- 8.5.2.2 Laboratory Media and Chemicals -- 8.5.2.3 Raw Materials Including Packaging Materials -- 8.5.2.4 Utilities -- 8.5.2.5 Working Capital (Tables 8.16, 8.17, and 8.18) -- 8.5.2.6 Income of 42 Ton/60,000 Bottle Selling of Vinegar -- References -- Chapter 9: Mass Multiplication, Production Cost Analysis and Marketing of Polyhydroxyalkanoates (PHAs) -- 9.1 Introduction -- 9.1.1 General -- 9.2 PHA Production -- 9.2.1 PHA Productivity and Bacterial Fermentation -- 9.2.2 Influence of Carbon Source on PHAs Production -- 9.2.3 Influence of Nitrogen Source on PHAs Production -- 9.3 PHA Production Cost Analysis -- 9.4 Marketing and Positioning of PHAs -- 9.5 Conclusion. , References -- Chapter 10: Small, Large-Scale Production and Cost-Benefit Analysis and Marketing of Agar from Gelidium -- 10.1 Introduction -- 10.2 Agar -- 10.2.1 Gelidium -- 10.2.2 Taxonomic Details of Gelidium Amansii -- 10.3 Small- and Large-Scale Production of Agar -- 10.3.1 Extraction of Agar from Seaweed -- 10.3.2 Cultivation of Seaweed -- 10.3.3 Main Seaweed Cultivation Techniques -- 10.3.3.1 Line Cultivation -- 10.3.3.2 Net Farming -- 10.3.3.3 Tank or Pond Farming -- 10.3.3.4 Minor or Experimental Methods -- 10.4 Cost and Market Analysis -- 10.4.1 Agar Market Overview -- 10.4.2 Agar Market Segment -- 10.4.3 Agar Market Opportunities -- 10.4.4 Agar Market: Growth Dynamics -- 10.4.5 Agar Market Trends -- 10.4.6 Agar Market Challenge -- 10.4.7 Agar Market: Regional Assessment -- 10.4.8 Production Cost Analysis -- 10.5 Future Perspective of the Seaweed Industry -- 10.6 Conclusion -- References -- Chapter 11: Mass Production of Valuable Pro-Vitamin a Pigment from a Microbe, Cost Analysis and Targeting It for Health Benefi... -- 11.1 Introduction -- 11.2 Different Sources of Natural Pigments -- 11.2.1 Plants -- 11.2.1.1 Chlorophyll -- 11.2.1.2 Carotenoids -- 11.2.1.3 Anthocyanins -- 11.2.1.4 Flavonoids -- 11.2.2 Minerals -- 11.2.3 Animal -- 11.2.4 Microbial and Fungal Origin -- 11.2.4.1 Crucial Factors for Pigment Production by Microorganisms -- 11.3 Importance of Natural Pigments over Synthetic Pigments -- 11.4 Production of Natural Pigments by Microbial Fermentation -- 11.4.1 Type of Fermentation -- 11.4.1.1 Solid-State Fermentation -- 11.4.1.2 Submerged Fermentation (SmF)/Liquid Fermentation (LF) -- 11.4.1.3 Different Modes of Operation of Submerged Fermentation for Microbial Pigment Production -- 11.4.1.4 Factors Influencing SSF and SMF -- Microorganism -- Temperature -- pH -- Aeration Rate -- Particle Size -- Agitation/Mixing. , Design of Bioreactors -- 11.4.2 Isolation and Identification of Pigment-Producing Microbe -- 11.4.2.1 Screening and Strain Development -- Sample Collection -- Isolation, Selection, and Screening of Microbes -- Primary Screening -- Secondary Screening -- 11.4.3 Bacterial Identification through Gene Sequencing Technique and Strain-Level Analysis -- 11.4.4 Genome Database and Phylogenetic Analysis -- 11.5 Strain Development of Microbe Using Metabolic Engineering -- 11.6 Process Optimization to Obtain High Yield Pigment Production -- 11.6.1 Statistical Approach for Microbial Pigment Production Optimization -- 11.7 Downstream Processing of Microbial Pigment -- 11.7.1 Alternative Method for VOCs Pigment Extraction -- 11.8 Characterization and Quantification of Carotenoids -- 11.9 Production of Microbial Pigment at Industrial Scale -- 11.10 Stability of Extracted Microbial Pigment -- 11.11 Applications of Carotenoids through Delivery System -- 11.11.1 Conventional Emulsions -- 11.11.2 Multilayer Emulsions -- 11.11.3 Solid-Lipid Particles (SLPs) -- 11.11.4 Liposomes -- 11.12 Applications of Carotenoid in Different Industry So Far -- 11.12.1 Food Industry -- 11.12.2 Pharmaceutical Industry -- 11.12.3 Cosmetics Industry -- 11.13 Cost Analysis for Microbial Pigment Production -- 11.14 Marketing of Microbial Carotenoid Pigment -- 11.15 Conclusion -- References -- Chapter 12: Pseudomonas Species-Derived Chitinase Mass Multiplication, Production Cost Analysis, and Marketing: As a Biocontro... -- 12.1 Introduction -- 12.2 General Characteristics of Pseudomonas Species -- 12.3 Chitinase and Its Role -- 12.4 Methods for the Mass Multiplication of Pseudomonas species -- 12.5 Formulation Development -- 12.5.1 Different Methods of Extraction of Chitinase from Bacteria (Pseudomonas Species) -- 12.6 Liquid Fermentation of Chitinase Enzyme. , 12.7 Solid-State Fermentation and Submerged Fermentation.
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  • 2
    Online Resource
    Online Resource
    Singapore : Springer Nature Singapore | Singapore : Imprint: Springer
    Keywords: Industrial microbiology. ; Microbiology—Technique. ; Microbiology.
    Description / Table of Contents: 1.Microbiology Based Entrepreneurship -- 2. Mass multiplication, production cost analysis and marketing of protease -- 3. Mass multiplication, production cost analysis and marketing of xylanase -- 4. Mass multiplication, production cost analysis and marketing of cellulase -- 5. Mass multiplication, production cost analysis and marketing of pectinase -- 6. Production, cost analysis, and marketing of Citric acid -- 7. Production, cost analysis and Marketing of Lactic acid -- 8. Production, cost analysis and marketing of acetic acid (vinegar) -- 9. Mass Multiplication, Production Cost Analysis and Marketing of Polyhydroxyalkanoates (PHAs) -- 10. Small, large-scale production and cost-benefit analysis and marketing of agar from Gelidium -- 11. Mass production of valuable pro-vitamin A pigment from a microbe, cost analysis and targeting it for health benefiting purpose -- 12. Pseudomonas species derived chitinase mass multiplication, production cost analysis, and marketing: as a biocontrol agent for crop protection -- 13. Production, cost analysis and marketing of Bio-organic Liquid Fertilizers and Plant Nutrition Enhancer -- 14. Production, cost analysis and marketing of agricultural effective microorganisms -- 15. Production, cost analysis and marketing of biogas -- 16. Mass Production and Marketing of Compost Caterpillar Fungus Cordyceps sinensis -- 17. Mass Production Methods, Market and Applications of Chitosan & Chitin Oligomer as a Biostimulant -- 18. Mass Multiplication and Production Cost Analysis and Marketing of Phosphate Solubilizing Microorganisms (PSM) -- 19. Large scale production and Business plan for Novel Corona Vaccine.
    Type of Medium: Online Resource
    Pages: 1 Online-Ressource(XXI, 323 p. 1 illus.)
    Edition: 1st ed. 2022.
    ISBN: 9789811966644
    Series Statement: Microorganisms for Sustainability 42
    Language: English
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical & experimental allergy 19 (1989), S. 0 
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Pneumococcus has been shown to bind to epithelial cells of the nasopharynx and lung, and to endothelial cells of the peripheral vasculature. To characterize bacterial elements required for attachment to these cell types, a library of genetically altered pneumococci with defects in exported proteins was screened for the loss of attachment to glycoconjugates representative of the nasopharyngeal cell receptor, type II lung cells (LC) and human endothelial cells (EC). A mutant was identified which showed a greater than 70% loss in the ability to attach to all cell types. This mutant also showed decreased adherence to the glycoconjugates containing the terminal sugar residues GalNAcβ1-3Gal, GalNAcβ1-4Gal and the carbohydrate GlcNAc, which are proposed components of the pneumococcal receptors specific to the surfaces of LC and EC. Analysis of the locus altered in this mutant revealed a gene, spxB, that encodes a member of the family of bacterial pyruvate oxidases which decarboxylates pyruvate to acetyl phosphate plus H2O2 and CO2. This mutant produced decreased concentrations of H2O2 and failed to grow aerobically in a chemically defined medium, unless supplemented with acetate which presumably restores acetyl phosphate levels by the action of acetate kinase, further suggesting that spxB encodes a pyruvate oxidase. The addition of acetate to the growth medium restored the adherence properties of the mutant indicating a link between the enzyme and the expression of bacterial adhesins. A defect in spxB corresponded to impaired virulence of the mutant in vivo. Compared to the parent strain, an spxB mutant showed reduced virulence in animal models for nasopharyngeal colonization, pneumonia, and sepsis. We propose that a mutation in spxB leads to down-regulation of the multiple adhesive properties of pneumococcus which, in turn, may correlate to diminished virulence in vivo
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Pneumococci adhere to but fail to enter resting human endothelial cells but can be visualized inside an intracellular compart-ment upon inflammatory activation of the cells3. To determine whether activation affords penumococci a specific route of ...
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Kay and his colleagues [1] have suggested that the neutrophil high molecular weight chemotactic factor (NCF) found in the serum of patients suffering from a variety of allergic diseases is mainly derived from mast cells and is therefore an indicator of mast cell activation. We have studied some of the properties of NCF obtained from patients with atopic extrinsic asthma and compared it withN-formyl-1-methionyl-1-leucyl-1-phenylalanine (FMLP), a chemotactic peptide [2]. A number of differences between FMLP and NCF were observed. In contrast to FMLP, checkerboard analysis showed that NCF caused random migration of neutrophils. In addition microscopic analysis of neutrophil locomotion in response to FMLP demonstrated the characteristic pseudopod formation. Furthermore, it was found that in contrast to FMLP, NCF did not cause the release of lysosomal enzymes from cytochalasin B-treated neutrophils. These results suggest that NCF has chemokinetic rather than chemotactic properties.
    Type of Medium: Electronic Resource
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