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  • 1
    Publication Date: 2016-03-03
    Description: Longitudinal qPCR monitoring of nucleophosmin 1 mutations after allogeneic hematopoietic stem cell transplantation to predict AML relapse Bone Marrow Transplantation 51, 466 (March 2016). doi:10.1038/bmt.2015.296 Authors: E Xue, C Tresoldi, E Sala, A Crippa, B Mazzi, R Greco, C Messina, M G Carrabba, M T Lupo Stanghellini, S Marktel, C Corti, J Peccatori, M Bernardi, F Ciceri & L Vago
    Print ISSN: 0268-3369
    Electronic ISSN: 1476-5365
    Topics: Medicine
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  • 2
    Publication Date: 2020-12-15
    Description: The seismic sequence that occurred in the Abruzzo Apennines near L’Aquila (Italy) in April 2009 caused extensive damage and a large number of casualties (more than 300). The earthquake struck an area in the Italian Apennines chain where several faults, belonging to adjacent seismotectonic domains, create a complex tectonic regime resulting from the interaction among regional stress buildup, local stress changes caused by individual earthquakes, and viscous-elastic stress relaxation. Understanding such complex interaction in the Apennines can lead to a large step forward in the seismic risk mitigation in Italy. The Abruzzo earthquake has been very well recorded by interferometric synthetic aperture radar (InSAR) data, much better than the first Italian earthquake ever recorded by satellites, namely, the 1997 Umbria–Marche earthquake. ENVISAT (ENVIronmental SATellite) data for the Abruzzo earthquake are, in fact, very clear and allow an accurate reconstruction of the faulting mechanism. We present here an accurate inversion of vertical deformation data obtained by ENVISAT images, aimed to give a detailed reconstruction of the fault geometry and slip distribution. The resulting fault models are then used to compute, by a suitable theoretical model based on the elastic dislocation theory, the stress changes induced on the neighboring faults. The correlation of the subsequent mainshocks and aftershocks of the Abruzzo sequence with the volumes undergoing increasing Coulomb stress clearly evidence the triggering effect of coseismic stress changes on further seismicity. Moreover, this analysis put in evidence which seismotectonic domains have been more heavily charged by stress released by the Abruzzo mainshocks. The most important faults significantly charged by the Abruzzo sequence belong to the Sulmona and Avezzano tectonic domains. Taking into account the average regional stress buildup in the area, the positive Coulomb stress changes caused by this earthquake can be seen as anticipating the next earthquakes in the neighboring domains of 15–20 yr.
    Description: Published
    Description: 2340–2354
    Description: JCR Journal
    Description: restricted
    Keywords: Earthquakes of April 2009 ; 04. Solid Earth::04.07. Tectonophysics::04.07.99. General or miscellaneous
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 3
    Publication Date: 2022-06-14
    Description: An innovative approach to seismic hazard assessment is illustrated that, based on the available knowledge of the physical properties of the Earth structure and of seismic sources, on geodetic observations, as well as on the geophysical forward modeling, allows for a time-dependent definition of the seismic input. According to the proposed approach, a fully formalized system integrating Earth Observation data and new advanced methods in seismological and geophysical data analysis is currently under development in the framework of the Pilot Project SISMA, funded by the Italian Space Agency. The synergic use of geodetic Earth Observation data (EO) and Geophysical Forward Modeling deformation maps at the national scale complements the space- and time-dependent information provided by real-time monitoring of seismic flow (performed by means of the earthquake prediction algorithms CN and M8S) and permits the identification and routine updating of alerted areas. At the local spatial scale (tens of km) of the seismogenic nodes identified by pattern-recognition analysis, both GNSS (Global Navigation Satellite System) and SAR (Synthetic Aperture Radar) techniques, coupled with expressly developed models for interseismic phase, allow us to retrieve the deformation style and stress evolution within the seismogenic areas. The displacement fields obtained from EO data provide the input for the geophysical modeling, which eventually permits to indicate whether a specific fault is in a “critical state.” The scenarios of expected ground motion (shakemaps) associated with the alerted areas are then defined by means of full waveforms modeling, based on the possibility to compute synthetic seismograms by the modal summation technique (neo-deterministic hazard assessment). In this way, a set of deterministic scenarios of ground motion, which refer to the time interval when a strong event is likely to occur within the alerted area, can be defined both at national and at local scale. The considered integrated approach opens new routes in understanding the dynamics of fault zones as well as in modeling the expected ground motion. The SISMA system, in fact, provides tools for establishing warning criteria based on deterministic and rigorous forward geophysical models and hence allows for a well-controlled real-time prospective testing and validation of the proposed methodology over the Italian territory. The proposed approach complements the traditional probabilistic approach for seismic hazard estimates, since it supplies routinely updated information useful in assigning priorities for timely mitigation actions and hence it is particularly relevant to Civil Defense purposes.
    Description: Published
    Description: 1179–1198
    Description: 2T. Deformazione crostale attiva
    Description: JCR Journal
    Keywords: seismic hazard ; earth observation ; GPS ; DInSAR ; earthquake prediction ; ground shaking scenarios ; seismic input
    Repository Name: Istituto Nazionale di Geofisica e Vulcanologia (INGV)
    Type: article
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  • 4
    Publication Date: 2020-02-12
    Keywords: 550 - Earth sciences
    Type: info:eu-repo/semantics/conferenceObject
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