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  • 1
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    (Table 2) Bacteriohopanepolyol biomarkers in surface sediments of the Congo fan (2008)
    PANGAEA
    Details
    Publication Date: 2024-02-02
    Keywords: Adenosylhopane, per unit mass total organic carbon; Aminotriol, per unit mass total organic carbon; Carbon, organic, total; Depth, bottom/max; DEPTH, sediment/rock; Depth, top/min; Eastern Niger fan; Elevation of event; Event label; GeoB4901-2; GeoB4909-7; GeoB4913-4; GeoB4917-2; Latitude of event; Longitude of event; M41/1; Meteor (1986); MUC; MultiCorer; Non-nitrogen containing bacteriohopanepolyol biomarkers, per unit mass total organic carbon; Non-nitrogen containing bacteriohopanepolyol biomarkers cyclitol ether, per unit mass total organic carbon; northern Congo fan; off Angola; off Gabun; PROFILUR; PROFILUR Lander
    Type: Dataset
    Format: text/tab-separated-values, 23 data points
    Location Call Number Limitation Availability
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    DATA PANGAEA
  • 2
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    Bacteriohopanepolyol biomarkers of sediments from the Congo fan (2008)
    PANGAEA
    In:  Supplement to: Cooke, M P; Talbot, Helen M; Wagner, Thomas (2008): Tracking soil organic carbon transport to continental margin sediments using soil-specific hopanoid biomarkers: A case study from the Congo fan (ODP site 1075). Organic Geochemistry, 39(8), 965-971, https://doi.org/10.1016/j.orggeochem.2008.03.009
    Details
    Publication Date: 2024-02-02
    Description: The transport and deposition of terrestrially derived organic matter (TOM) into the ocean is an important but poorly constrained aspect of the modern global carbon cycle. A preliminary study of Late Quaternary sediments from the Congo deep sea fan (ODP leg 175, site 1075, 2 km water depth) and four surface samples from associated cores has confirmed the presence of proposed soil-specific bacteriohopanepolyol biomarkers (BHPs) including adenosylhopane, in samples to a depth of 89 m. Concentrations of soil marker BHPs are high in the upper sediment section (to 49 m) and the closest related surface sample (4913), supporting the case for these molecular markers as novel proxies for soil organic carbon (SOC) supply via riverine transport and subsequent burial. Distinct peaks for the markers at about 21, 34 and 60 m below surface level tentatively imply that the rate of TOM discharge from tropical Africa significantly increased at these times, possibly associated with periods of reduced soil stability in the Congo catchment.
    Keywords: 175-1075; Benguela Current, South Atlantic Ocean; COMPCORE; Composite Core; Eastern Niger fan; GeoB4901-2; GeoB4909-7; GeoB4913-4; GeoB4917-2; Joides Resolution; Leg175; M41/1; Meteor (1986); MUC; MultiCorer; northern Congo fan; Ocean Drilling Program; ODP; off Angola; off Gabun; PROFILUR; PROFILUR Lander
    Type: Dataset
    Format: application/zip, 2 datasets
    Location Call Number Limitation Availability
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    DATA PANGAEA
  • 3
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    (Table 3) Bacteriohopanepolyol biomarkers in ODP Site 175-1075 (2008)
    PANGAEA
    Details
    Publication Date: 2024-02-02
    Keywords: 175-1075; 2-Methyl non-nitrogen containing bacteriohopanepolyol biomarkers cyclitol ether, per unit mass total organic carbon; 32,35-Anhydro non-nitrogen containing bacteriohopanepolyol biomarkers, per unit mass total organic carbon; Adenosylhopane, per unit mass total organic carbon; AGE; Aminotetrol, per unit mass total organic carbon; Aminotriol, per unit mass total organic carbon; Benguela Current, South Atlantic Ocean; BHhexol cyclitol ether, per unit mass total organic carbon; BHpentol cyclitol ether, per unit mass total organic carbon; Carbon, organic, total; COMPCORE; Composite Core; DEPTH, sediment/rock; Joides Resolution; Leg175; Methyladenosylhopane, per unit mass total organic carbon; Non-nitrogen containing bacteriohopanepolyol biomarkers, per unit mass total organic carbon; Non-nitrogen containing bacteriohopanepolyol biomarkers cyclitol ether, per unit mass total organic carbon; Non-nitrogen containing bacteriohopanepolyol biomarkers glucosamine, per unit mass total organic carbon
    Type: Dataset
    Format: text/tab-separated-values, 195 data points
    Location Call Number Limitation Availability
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    DATA PANGAEA
  • 4
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    Distribution of polar membrane lipids in permafrost soils and sediments of a small high Arctic catchment (2010)
    In:  EPIC3Organic Geochemistry, 41(10), pp. 1130-1145
    Details
    Publication Date: 2019-07-17
    Repository Name: EPIC Alfred Wegener Institut
    Type: Article , isiRev
    Location Call Number Limitation Availability
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    PAPER (OA)
  • 5
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    The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain (2013)
    Rockefeller University Press
    Details
    Publication Date: 2013-01-15
    Description: B cell development requires tight regulation to allow for the generation of a diverse repertoire while preventing the development of autoreactive cells. We report, using N -ethyl- N -nitrosourea (ENU)–induced mutagenesis, the identification of a mutant mouse (chompB) with a block in early B cell development. The blockade occurs after the transitional 1 (T1) stage and leads to a decrease in mature B cell subsets and deficits in T cell–dependent antibody responses. Additionally, chompB mice have decreases in myeloid dendritic cells (DCs). The mutation was mapped to the intramembrane protease signal peptide peptidase-like 2a (Sppl2a), a gene not previously implicated in immune cell development. Proteomic analysis identified the invariant chain (CD74) as a key substrate of Sppl2a and suggests that regulated intramembrane proteolysis of CD74 by Sppl2a contributes to B cell and DC survival. Moreover, these data suggest that modulation of Sppl2a may be a useful therapeutic strategy for treatment of B cell dependent autoimmune disorders.
    Keywords: Lymphocyte Biology
    Print ISSN: 0022-1007
    Electronic ISSN: 1540-9538
    Topics: Medicine
    Published by Rockefeller University Press
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    PAPER CURRENT
  • 6
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    PDGFR antagonist regulates megakaryopoiesis [Cell Biology] (2012)
    National Academy of Sciences
    Details
    Publication Date: 2012-08-29
    Description: Molecules that control the lineage commitment of hematopoietic stem cells (HSCs) may allow the expansion of enriched progenitor populations for both research and therapeutic uses. In an effort to better understand and control the differentiation of HSCs to megakaryocytes, we carried out an image-based screen of a library of 50,000...
    Print ISSN: 0027-8424
    Electronic ISSN: 1091-6490
    Topics: Biology , Medicine , Natural Sciences in General
    Published by National Academy of Sciences
    Location Call Number Limitation Availability
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    PAPER CURRENT
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