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  • 1
    Online Resource
    Online Resource
    Therapeutic Potential of Melatonin : 2nd Locarno Meeting on Neuroendocrinology, Locarno, May 1996. (1997)
    Basel :S. Karger AG,
    Details
    Keywords: Electronic books.
    Type of Medium: Online Resource
    Pages: 1 online resource (182 pages)
    Edition: 1st ed.
    ISBN: 9783318002287
    Series Statement: Frontiers of Hormone Research Series ; v.23
    URL: https://ebookcentral.proquest.com/lib/geomar/detail.action?docID=3016541
    Language: English
    Note: Intro -- Contents -- Preface -- Foreword -- The Pars tuberalis - A Pituitary Target for Melatonin -- The Nocturnal Melatonin Peak and the Photoperiodic Response -- Nuclear Signalling of Melatonin1 -- Expression ofMembraneMelatonin Receptor mRNA in Rat Thymus and Spleen1 -- Mechanisms of Action of Melatonin on the Human Immune System1 -- Melatonin Rhythm in Mice and Its Role in Autoimmune Diseases -- New T Helper Cell Opioid Cytokines as Mediators of the Immunological and Hematopoietic Action of Melatonin -- The Protective Effect of Melatonin in Viral and Bacterial Infections1 -- Cellular and Molecular Actions of Melatonin as an Antioxidant -- Melatonin Reduces the Expression of Excitotoxicity-Triggered Markers of Apoptosis1 -- Relationship between the Pineal Gland and Experimentally Induced Malignant Tumors -- Melatonin Suppression of Tumor Growth in vivo: A Novel Mechanism Involving Inhibition of Fatty Acid Uptake and Metabolism -- Modulation of Melatonin Secretion in Cancer Patients -- Association of Melatonin with Nuclear Grade and Estrogen Receptor Status in Human Breast Cancer -- Melatonin as a Modulator of Cancer Endocrine Therapy -- Presurgical Neuroimmunotherapy with Melatonin and Interleukin-2 in Cancer Patients -- Melatonin - Shutting Off the Wakefulness System -- Potential Therapeutic Effects of Melatonin -- Subject Index.
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  • 2
    Electronic Resource
    Electronic Resource
    Capacitance, transepidermal water loss and causal level of sebum in healthy subjects in relation to site, sex and age (1995)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of cosmetic science 17 (1995), S. 0 
    Details
    ISSN: 1468-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: To determine normal levels of transepidermal water loss (TEWL), capacitance and sebum according to different sex and age groups, 93 healthy subjects were studied at 14 different anatomical locations with three different instruments: the Evaporimeter EP 1, the Corneometer CM 820, and the Sebumeter SM 810, evaluating respectively the transepidermal water loss, the capacitance and the causal level of sebum. Differences depending on the anatomical site were noticed. Unlike the capacitance, the transepidermal water loss and the causal level of sebum significantly decreased according to age. Furthermore, in some sites, male subjects showed a significantly higher transepidermal water loss than females, while hydration of the horny layer expressed by the capacitance showed an opposite trend. Correlations between the above-mentioned skin parameters were calculated: a positive correlation between TEWL and hydration was observed only at plantar and palmar areas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1467-2494.1995.tb00111.x
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  • 3
    Electronic Resource
    Electronic Resource
    Seasonal influences on stratum corneum ceramide 1 fatty acids and the influence of topical essential fatty acids (1996)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of cosmetic science 18 (1996), S. 0 
    Details
    ISSN: 1468-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Ceramide 1 is the main repository of stratum corneum linoleic acid, and changes in the levels of ceramide 1 linoleate are associated with cutaneous abnormalities: essential fatty acid deficiency, atopic dermatitis and acne. We have previously reported seasonal variation in stratum corneum lipids where lipids, particularly ceramides, are very much reduced in winter which probably influences the appearance of skin xerosis in this season. However, investigations into the seasonal variation in ceramide 1 fatty acid levels and the effects of topical essential fatty acids on the composition of these lipid species have not been conducted in healthy subjects. We determined the composition of stratum corneum ceramide 1 esterified fatty acids in leg skin from Caucasian women in winter and summer and also investigated the effects of topical triglycerides rich in linoleic acid on stratum corneum ceramide 1 fatty acid levels in winter. A dramatic seasonal variation was observed. Whereas decreased levels of linoleic acid and some saturated fatty acids (C-15 and C-24) were observed in the winter months, increased levels of oleic acid were found. Nevertheless, it was possible to normalize the levels of stratum corneum ceramide 1 linoleate following topical application of formulations containing linoleic acid-rich triglycerides for 4 weeks. The reduction in ceramide 1 linoleate may lead to impaired stratum corneum function and increased susceptibility to skin xerosis in winter. However, by using formulations containing linoleic acid esters it is possible to correct these changes and possibly improve barrier resilience.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1467-2494.1996.tb00131.x
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  • 4
    Electronic Resource
    Electronic Resource
    Differences in performance, flesh composition and water output quality in relation to density and feeding levels in rainbow trout, Oncorhynchus mykiss (Walbaum), farming (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Aquaculture research 25 (1994), S. 0 
    Details
    ISSN: 1365-2109
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract. The aim of this research was lo evaluate the effect of density and feeding level (initially 8 or 16kg/m3 and 1·3% or 2% of present biomass respectively) on productive traits, meat composition and water quality output in farmed rainbow trout, Oncorhynchus mykiss (Walbaum). Individual fish growth shows significant differences in relation to density and feeding level; feed conversion rate is positively Influenced by the lower feeding level and low rearing density. At low density, specific growth rate, protein efficiency ratio and coefficient of variation of individual final weights are more favourable than at high density. Dry matter and lipid composition of meat are positively affected by feeding level; whereas no differences are recorded on the amino acid and fatty acid profiles. Water quality shows differences due to density (NO3 and NH4+) and feeding level (NO2, NH4+ and P).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2109.1994.tb00728.x
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  • 5
    Electronic Resource
    Electronic Resource
    In vivo assessment of n-alkyl-sulfate-induced skin irritation by means of non-invasive methods (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Skin research and technology 4 (1998), S. 0 
    Details
    ISSN: 1600-0846
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background/aims: Sodium lauryi sulfate (SLS) is the most frequently used model for studying in vivo irritation. It is also one of the most frequent surfactants in soap preparations and cosmetic emulsions. To investigate the irritant potential of sodium salts of n-alkyl sulfates with different carbon chain length (n=8, 12, 14), we applied these substances on the volar forearm of 10 healthy human volunteers aged 24 to 35 years.Methods: To allow the equal solubilization of the surfactants, we used a 0.2% solution (w/v). A colorimeter to assess erythema, an evaporimeter to assess transepidermal water loss (TEWL) and a corneometer to evaluate skin hydration were employed to estimate the effects of the chemicals on the skin. Evaluations were performed at baseline, 24, 48 and 72 h.Results: TEWL had increased at 24 h: SLS showed the highest increase, followed by octyl and tetradecyl sulfate. Skin hydration was reduced for the three substances, and a slight increase in redness was noticed. TEWL and hydration values at different times of assessment enabled the ranking of n-alkyl sulfates in the following order: lauryi sulfate, tetradecyl sulfate and octyl sulfate.Conclusions: We could not prove a direct correlation between barrier impairment, skin dehydration and surfactant-induced inflammation, as evaluated by color measurements. This discrepancy suggests that the irritation potential of n-alkyl sulfates at the dermal level differs from their action on skin barrier.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0846.1998.tb00109.x
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  • 6
    Electronic Resource
    Electronic Resource
    Lettuce anaphylaxis: identification of a lipid transfer protein as the major allergen (2003)
    Oxford, UK : Munksgaard International Publishers
    Allergy 58 (2003), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background:  Allergy to plant-derived foods is associated with birch pollinosis in central and northern Europe. Symptoms elicited are usually limited to the oropharyngeal system. By contrast, in the Mediterranean area, allergy to the same foods manifests more frequently with systemic reactions caused by nonspecific lipid transfer proteins (nsLTP), independently of an associated pollinosis.Objective:  We sought to investigate the pattern of immunoglobulin E (IgE) binding protein bands implicated in lettuce allergy, in particular the presence of an nsLTP.Methods:  Consecutive lettuce allergic patients were selected. Determination of serum-specific IgE, immunoblot, and inhibition experiments were performed in order to study the pattern of IgE binding proteins and the potential cross-reactivity to pollens. Inhibition studies with recombinant allergens were conducted to identify the lettuce allergens. The major allergen was subjected to N-terminal amino acid sequencing.Results:  Fourteen patients were diagnosed as being allergic to lettuce. All were sensitized to Platanus pollen. Ten of them showed specific IgE to a lettuce protein of 9-kDa. The IgE binding to this protein was completely inhibited by the cherry-LTP and peach extract. The N-terminal sequence of the 9-kDa protein showed a high degree of amino acid sequence identity to other nsLTPs. A clear partial cross-reactivity was observed between lettuce-LTP and Platanus-pollen extract.Conclusions:  An LTP has been demonstrated to be a major allergen in patients suffering from lettuce allergy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1398-9995.2003.00097.x
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  • 7
    Electronic Resource
    Electronic Resource
    Release of Extracellular Matrix Components by Bovine Bone Endothelial Cells in Continuous Culture
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 190 (1993), S. 502-508 
    Details
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1006/bbrc.1993.1076
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  • 8
    Electronic Resource
    Electronic Resource
    Isolation of a new ligand-carrying casein fragment from bovine mammary gland microsomes
    Amsterdam : Elsevier
    FEBS Letters 305 (1992), S. 189-191 
    Details
    ISSN: 0014-5793
    Keywords: Casein ; Mammary gland, β-Lactoglobulin ; Retinol transport
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0014-5793(92)80664-3
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  • 9
    Electronic Resource
    Electronic Resource
    A new dispersion relation for Kaon-Nucleon scattering - II. K-matrix parametrization of the low-energy region
    Amsterdam : Elsevier
    Nuclear Physics, Section B 70 (1974), S. 116-124 
    Details
    ISSN: 0550-3213
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0550-3213(74)90361-7
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  • 10
    Electronic Resource
    Electronic Resource
    A new dispersion relation for kaon-nucleon scattering I. Constant scattering length parametrization of the low-energy region
    Amsterdam : Elsevier
    Nuclear Physics, Section B 42 (1972), S. 607-619 
    Details
    ISSN: 0550-3213
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0550-3213(72)90501-9
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