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  • 1
    Publication Date: 2018-06-05
    Description: Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins, Published online: 04 June 2018; doi:10.1038/s41589-018-0082-8 Potent pan-Atg8 or GABARAP-selective inhibitory peptides derived from giant neuronal ankyrin-B and -G effectively block autophagy in cell cultures and in C. elegans spatiotemporally.
    Print ISSN: 1552-4450
    Electronic ISSN: 1552-4469
    Topics: Biology , Chemistry and Pharmacology
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  • 2
    Publication Date: 2015-03-24
    Description: Results are presented from a series of numerical studies designed to investigate the atmospheric boundary layer structure, ambient wind, and pollutant source location and their impacts on the wind field and pollutant distribution within the built-up areas of Shenyang, China. Two models, namely, Open Source Field Operation and Manipulation (OpenFOAM) software package and Weather Research and Forecasting (WRF) model, are used in the present study. Then the high resolution computational fluid dynamics (CFD) numerical experiments were performed under the typical simulated atmospheric boundary conditions. It was found that the atmospheric boundary structure played a crucial role in the pollution within the building cluster, which determined the potential turbulent diffusion ability of the atmospheric surface layer; the change of the ambient wind direction can significantly affect the dispersion pattern of pollutants, which was a more sensitive factor than the ambient wind speed; under a given atmospheric state, the location of the pollution sources would dramatically determine the pollution patterns within built-up areas. The WRF-CFD numerical evaluation is a reliable method to understand the complicated flow and dispersion within built-up areas.
    Print ISSN: 1687-9309
    Electronic ISSN: 1687-9317
    Topics: Geosciences , Physics
    Published by Hindawi
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