ISSN:
1542-474X
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
QT dispersion (QTd) represents the inhomogeneity of ventricular repolarization and has been reported to predict ventricular tachyarrhythmias in postmyocardial infarction patients. This study investigates the short-term effect of percutaneous transluminal coronary angioplasty (PTCA) on QTd in patients with coronary artery disease (CAD) and no history of previous myocardial infarction.〈section xml:id="abs1-2"〉〈title type="main"〉MethodsIn 84 angina patients (65 men and 19 women, mean age, 58.3 ± 9.0 years) who underwent successful PTCA of a single coronary artery, ECG was recorded in baseline, immediate, 1 day, and 1 month after PTCA for measurement of QTd and corrected QTd (c-QTd).〈section xml:id="abs1-3"〉〈title type="main"〉ResultsPTCA was performed at the left anterior descending artery (LAD) in 56, left circumflex artery (LCx) in 12, and right coronary artery (RCA) in 16 patients. QTd (c-QTd) at baseline, immediately, 1 day, and 1 month following PTCA was 51.3 ± 4.2 (50.7 ± 4.1), 54.2 ± 4.5 (52.8 ± 4.5), 47.7 ± 4.3 (48.5 ± 4.8), and 36.3 ± 4.5 (37.5 ± 4.6) ms, respectively. QTd and c-QTd significantly decreased at 1 month following PTCA. The difference was more prominent in patients with LAD lesion than LCx or RCA lesion, independent of gender, severity of stenosis, and use of beta-blocker.〈section xml:id="abs1-4"〉〈title type="main"〉ConclusionsQTd decreases in CAD patients with no history of myocardial infarction at 1 month following successful PTCA. This suggests that PTCA facilitates a favorable recovery from inhomogeneous repolarization due to myocardial ischemia. This finding calls for long-term follow-up of QTd and risk of ventricular tachyarrhythmias and sudden death following successful PTCA.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1542-474X.1999.tb00059.x
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