Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
British journal of dermatology
95 (1976), S. 0
ISSN:
1365-2133
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
We have investigated lymphocyte subpopulations (six different markers) and T cell functions (mitogen responses and serum thymic factor determination) in twenty patients with psoriasis compared with thirty-five healthy subjects. Normal results were found for B cell markers, but significantly lower numbers of T cells were assessed by E-rosettes and anti HTLA serum. Mitogen responses were normal for PHA but depressed after Con A and PWM stimulation. Lastly, thymic factor levels were significantly higher in psoriasis than in normal subjects of the same age.These findings could be in favour of a T cell subpopulation defect involved in an auto-immune pathogenesis of psoriasis.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1365-2133.1976.tb07017.x
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