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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of pineal research 5 (1988), S. 0 
    ISSN: 1600-079X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The adult dog pineal gland was studied with the electron microscope. Pineal connective tissue spaces were poorly developed and showed capillaries with nonfenestrated endothelial cells. Two cell types, pinealocytes and astrocytes, could be identified in pineal parenchyma. Dog pinealocytes showed microtubules, centrioles, occasional cilia, and well-developed Golgi complexes. These cells showed thin processes with bulbous endings packed with vesicles. Astrocytes were characterized by the presence of numerous filaments. Their processes finished forming a glial layer bordering connective tissue spaces. The presence of myelinated and unmyelinated nerve fibers was also described.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of pineal research 8 (1990), S. 0 
    ISSN: 1600-079X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The ultrastructure of the dog pineal gland from the first postnatal day to the seventh month is described. In the first postnatal stages, pineal parenchyma only shows immature proliferative cells with abundant cytoplasmic glycogen. Nerve fibers are seen in the pineal connective tissue spaces. The differentiation of the dog pineal cell types begins in the first postnatal week. Both pinealocytes and pigmented cells are first seen on the fourth postnatal day. The pineal astrocytes are observed on the tenth day. Immature cells are still found in the pineal gland of 1 mo-old dogs. The differentiation of the dog pineal cell types is completed by the second postnatal month.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of pineal research 1 (1984), S. 0 
    ISSN: 1600-079X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The pineal gland of rats 12–28 months old was studied with light and electron microscopes. All pineal components exhibited regressive changes of different intensity with age. In type I pinealocytes, there was a marked increase in dense bodies as well as the occasional appearance of wide cell profiles full of vesicles. Type II pinealocytes showed nuclear infoldings and cytoplasmic deposits of lipofuscin. Pineal stroma displayed an increase in connective tissue fibers, both collagen and oxytalan, as well as remains of basement membranes and other materials of unknown nature. Calcareous concretions were also found, mostly in the pineal capsule. All regressive changes were more intense with increasing age.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-0568
    Keywords: Pituitary gland ; Pars distalis ; Folliculo-stellate cell ; Marginal cell ; Vimentin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The occurrence of vimentin, a specific intermediate filament protein, has been studied by an indirect immunoperoxidase method in the anterior pituitary gland of adult rats, cats and rabbits of both sexes. In the three species studied, the immunoreaction product was detected in the cytoplasm of stellate-shaped cells scattered throughout the pars distalis. These stellate cells showed long cytoplasmic processes which could be seen between the secretory cells, and occasionally, encircling them. These processes sometimes reach the vasculo-connective septa. The marginal cells lining the anterior layer of the hypophyseal cleft of the rat and the cat pituitary glands also showed a positive immunoreaction. Finally, cyst or follicle-like structures lined by immunostained cells with basal processes could be observed in the anterior lobe of the rat, but not in that of the rabbit or the cat. These findings support the previously held view that folliculo-stellate cells and marginal cells of the anterior pituitary gland have a common nature and suggest that these cell types might be derived from glial neuroectodermic cells.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 200 (1981), S. 491-500 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The embryonic development of the albino rat pineal gland has been studied from day 13 of development until birth. The first pineal anlage appears as a midline evagination of the diencephalic roof, which soon adopts a tubular morphology. At 17 days, the disappearance of the pineal recess begins, along with the transformation of the gland into a solid organ. The latter is mainly achieved by an infolding and thickening of the dorsal recess wall, from which derives most of the future pineal parenchyma. Blood vessels are mainly derived from the vessels found in the dorsal surface of the pineal gland.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 220 (1988), S. 424-428 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Immunoperoxidase methods for the demonstration of three glial antigens, vimentin, glial fibrillary acidic protein, and S-100 protein, were applied to routine-fixed paraffin sections of rat pineal gland. A pre-embedding electron microscope immunoperoxidase method was also used to study the ultrastructural localization of S-100 protein in pineal cells. Light and electron microscopic results showed the presence of these antigenic glial markers in the second pineal cell type. The term glial cell is proposed for the second of parenchymatous cell in rat pineal gland.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 199 (1981), S. 543-553 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The ultrastructure of the albino rat embryo pineal gland was studied from day 13 of development through birth. In the first stages (13-16.5 days of development) the pineal evagination presents a barely differentiated epithelium. From 17 days onward the transformation of the pineal gland from a tubular evagination into a compact organ occurs. The obliteration of the recess takes place by means of two mechanisms: (a) multiple foldings of the epithelium which determine an approximation and fusion of the walls of the recess, and (b) occupation of the lumen by cells extruded from the pineal epithelium. Embryos of 18-21 days of gestation still show remains of the pineal recess.Frm day 16.5 onward elements of the pineal parenchyma have been found outside the pineal epithelium contour. They contact with the mesenchymal cells without a basal lamina separating both elements.Day 20 marks the beginning of recognizable differentiation of pineal cellular types. However, in the newborn rat these types are not yet clearly established.
    Additional Material: 14 Ill.
    Type of Medium: Electronic Resource
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