Description: Negative Cerium (Ce) anomalies are observed in chondrite-normalized Rare Earth Element patterns from various volcanic arc suites. These anomalies are well defined in volcanic rocks from the Mariana arc and have been interpreted as the result of addition of subducted sediments to the arc magma sources. This study combines 143Nd/144Nd and 138Ce/142Ce isotope measurements in Mariana volcanic rocks that have Ce anomalies ranging from 0.97 to 0.90. The dataset includes sediments sampled immediately before subduction at the Mariana Trench (Sites 801 and 802 of ODP Leg 129) and primitive basalts from the Southern Mariana Trough (back-arc basin). Binary mixing models between the local depleted mantle and an enriched end-member using both types of sediment (biosiliceous and volcaniclastic) found in the sedimentary column in front of the arc are calculated. Marianas arc lavas have Ce and Nd isotopic compositions that require〈2.5% of a sediment component derived from the volcaniclastics. With this proportion of sediment, most of the Ce/Ce* range measured in lavas is reproduced. Thus, this study confirms that the origin of the Ce anomalies in the Mariana arc magmas can be principally attributed to recycling of trench sediments through active subduction. The participation of a component derived from biosiliceous sediments does not explain the Ce-Nd isotope composition of the lavas because the involved proportion is too high (up to 8%) in comparison to results obtained from other geochemical proxys. Using this end-member, the modeled Ce anomalies are also too high (0.91–0.84) in comparison to those measured in lavas. Various processes and conditions are able to generate Ce anomalies: oxygen fugacity, residual mineral phases, partial melting, fractional crystallization and tropical weathering. Their influence in the case of Mariana volcanic arc magmas seems to be very limited but partial melting effect may explain the lowest measured Ce/Ce* values. Magmatic processes cannot be definitely ruled out in producing Ce anomalies in other arc system environments. Additional experimental data, however, are needed for a better understanding of the behavior of cerium relative to its neighboring elements. Also, this study highlights the importance of using local depleted mantle and sediments to model the isotopic compositions of arc lavas.