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  • 1
    Electronic Resource
    Electronic Resource
    Long-term results of corneal wedge resections for the correction of high astigmatism (1990)
    Springer
    Documenta ophthalmologica 75 (1990), S. 263-273 
    Details
    ISSN: 1573-2622
    Keywords: Cornea ; astigmatism ; astigmatic correction ; wedge resection ; keratoplasty
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We retrospectively evaluated 41 corneal wedge resections, performed for the correction of high astigmatism in 40 patients who were spectacle and contact lens intolerant. Keratometric astigmatism decreased from an average of 11.7 diopters (range 5 to 22.5 D) preoperatively to 3.5 diopters (range 0 to 10 D) postoperatively, representing a mean reduction of 8.2D (range 0 to 16.5), or 70%. The length of follow-up averaged 11 months. Twenty-five, 15 and 9 cases had a follow-up of at least 3, 5 and 10 years, respectively. In 16 cases the keratometry readings remained stable over the years. However, in 1 case of Fuchs' endothelial dystrophy (follow-up 13 years) and 5 cases of keratoconus (follow-up 3, 4, 12, 13 and 14 years) the astigmatism gradually increased during the various follow-up periods. In 3 other cases the astigmatism gradually decreased over the years. Corneal wedge resection is an effective technique for managing high corneal astigmatism. The results remain stable over the years except in some patients with keratoconus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00164840
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  • 2
    Electronic Resource
    Electronic Resource
    Infectious crystalline keratopathy (1987)
    Springer
    Documenta ophthalmologica 67 (1987), S. 95-103 
    Details
    ISSN: 1573-2622
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In seven patients white branched crystalline opacities, which grew very slowly, were seen in the corneal stroma. They were associated with very little inflammatory activity, so that the clinical picture at first did not suggest an infectious etiology. Pathological examination, however, demonstrated colonies of bacteria between intact corneal lamellae. On bacterial examination gram-positive commensals were mainly found. All the patients described so far were found to be taking corticosteroids regularly, sometimes in combination with antibiotics. The immunosuppression brought about by corticosteroids is probably an important factor in the development of these crystalline opacities. The therapy for this infectious crystalline keratopathy is difficult and lengthy. It consists of local bactericidal antibiotics and the lowest possible dosage of corticosteroids, if necessary combined with a partial lamellar keratectomy and removal of the affected corneal tissue by fraising.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00142703
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  • 3
    Electronic Resource
    Electronic Resource
    Causes of high astigmatism after penetrating keratoplasty (1993)
    Springer
    Documenta ophthalmologica 85 (1993), S. 21-34 
    Details
    ISSN: 1573-2622
    Keywords: Astigmatism ; Astigmatism correction ; Cornea ; Penetrating keratoplasty ; Wound healing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We retrospectively evaluated the factors which might have caused excessive corneal astigmatism after penetrating keratoplasty (PKP) in 29 eyes, in which surgical correction of astigmatism was indicated. In 18 eyes high astigmatism (5 diopters or more) existed before suture removal probably due to graft elevation (3×), wound dehiscence (3×), wound configuration abnormalities such as ovality/overcut (8×), and a thin recipient cornea (2×). The cause was unknown in 2 eyes. In 19 eyes the astigmatism considerably increased after all sutures were removed; astigmatism increased an average of 8.8 diopters (range, 5 to 16.5 D). Ten of these 19 patients showed graft elevation, despite the fact that the sutures were only removed after an average 22.9 months. In 3 other patients the astigmatism gradually increased over the years, long after suture removal; two of these showed graft elevation. The study demonstrates the possible instability of keratoplasty wounds, the change in astigmatism after suture removal, and the late apparently spontaneous changes in astigmatism after PKP in some eyes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01268097
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  • 4
    Electronic Resource
    Electronic Resource
    Mersilene (Polyester), a new suture for penetrating keratoplasty (1992)
    Springer
    Documenta ophthalmologica 82 (1992), S. 89-101 
    Details
    ISSN: 1573-2622
    Keywords: Keratometric astigmatism ; Mersilene suture ; Nylon suture ; Penetrating keratoplasty ; Suture adjustment ; Scanning electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Mersilene (polyester monofilament) seems to be suitable for penetrating keratoplasty because it is strong, shows no degradation by ultraviolet light, is insoluble, so that it can be left in situ, and offers the possibility of regulating postoperative astigmatism by suture adjustment. In 12 patients penetrating keratoplasty was performed with the combined interrupted/running suturing technique, using eight interrupted nylon 10-0 sutures and one running Mersilene 11-0 suture. The results were compared with those of 25 patients in whom eight interrupted nylon 10-0 sutures and one running nylon 11-0 suture were used. Six months after penetrating keratoplasty, no differences could be found between the two groups in keratometric astigmatism, visual acuity or slitlamp findings. In three patients postoperative adjustment of the running Mersilene suture reduced astigmatism by 50, 90 and 100% respectively. In an animal study the behaviour of Mersilene in the cornea was evaluated by slitlamp examination, histology and electron-microscopy. The tissue response to Mersilene was minimal. Considering the resemblance to nylon in clinical findings, minimal tissue response, lack of biodegradation and possibility of regulating postoperative astigmatism by suture adjustment, Mersilene seems to be a suitable material for penetrating keratoplasty.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00156998
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  • 5
    Electronic Resource
    Electronic Resource
    Long-term results of corneal transplantations in keratoconus patients (1985)
    Springer
    Documenta ophthalmologica 59 (1985), S. 93-97 
    Details
    ISSN: 1573-2622
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In this retrospective study all 86 corneal transplantations performed for keratoconus in the Rotterdam Eye Hospital between 1969 and 1978 were included. Sixtyseven perforating and 19 lamellar corneal grafts had been performed. The average follow-up was 59 months. Immune reactions occurred 12 times in 11 eyes with a perforating corneal graft (16%); in no case did this lead to permanent opacities in the graft. The visual result of the perforating graft is in general better than that of the lamellar graft. A lamellar graft is indicated, in our opinion, when the risk of trauma is high and the opportunities for follow-up insufficient, and when the peripheral cornea is markedly thin. In most cases we prefer a perforating graft because the results are better.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00162016
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  • 6
    Electronic Resource
    Electronic Resource
    Silico-acrylate contact lenses for extended wear (1986)
    Springer
    Documenta ophthalmologica 61 (1986), S. 313-317 
    Details
    ISSN: 1573-2622
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Extended wear contact lenses (EWCL) have been successfully used for the correction of aphakia. Disadvantages of soft EWCL are lens precipitates, lens loss and failure to correct higher astigmatic errors. Silico-acrylate rigid EWCL with high oxygen transmissibility have been used in this study to correct aphakia and higher astigmatic errors. Fourteen eyes were fitted with Boston IV lenses and observed for a mean of 6.5 months. All patients tolerated the rigid EWCL well without important complications. One patient discontinued lens wear because of discomfort without obvious clinical abnormalities. Rigid silico-acrylate EWCL are a reliable alternative for soft EWCL and are in some cases to be preferred to soft EWCL.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00142358
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  • 7
    Electronic Resource
    Electronic Resource
    Unusual deposits in the superficial corneal stroma following combined use of topical corticosteroid and beta-blocking medication (1991)
    Springer
    Documenta ophthalmologica 78 (1991), S. 169-175 
    Details
    ISSN: 1573-2622
    Keywords: Corneal calcinc precipitates ; epithelial defects ; steroids ; timolol
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Clinical observation of eight patients with superficial stromal precipitation of calcium phosphate is presented. In all cases the predisposing factors for the formation of these depositions were: epithelial defects and the combined use of topical dexamethason phosphate or prednisolon phosphate with topical beta-blocking agents. In two patients the medication that gave rise to these precipitates was used without preservatives, suggesting that the medication itself and not the preservatives contribute to the deposits. Discontinuance of simultaneous administration of the steroids and beta-blocking agents prevented further formation of precipitates. The authors suggest an interaction between simultaneously given steroid and betablocking agents, giving rise to calcium phosphate precipitates when an epithelial defect is present which allows easy access to the superficial corneal stroma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00165677
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  • 8
    Electronic Resource
    Electronic Resource
    Effect of donor cornea preservation in tissue culture and in McCarey-Kaufmann medium on corneal graft rejection and visual acuity (1991)
    Springer
    Documenta ophthalmologica 78 (1991), S. 273-278 
    Details
    ISSN: 1573-2622
    Keywords: Corneal preservation ; penetrating keratoplasty
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a retrospective study the rate of rejection and clouding of the donor cornea for other reasons was investigated in 230 penetrating keratoplasties performed between 1984–1986. Donor corneas were stored in McCarey-Kaufmann Medium (MK) at 4 °C or in a modified Minimal Essential Medium (MEM) at 31 °C. No statistical differences in rejection rate, cloudiness due to other causes or visual acuity was found between MEM- and MK-stored donor corneas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00165691
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  • 9
    Electronic Resource
    Electronic Resource
    Pseudophakic endophthalmitis (1992)
    Springer
    Documenta ophthalmologica 82 (1992), S. 109-114 
    Details
    ISSN: 1573-2622
    Keywords: Antimicrobial resistance ; Intravitreal antibiotics ; Pseudophakic endophthalmitis ; Staphylococcus epidermidis ; Vitrectomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We performed a retrospective study on 45 patients admitted to the Rotterdam Eye Hospital and the Ophthalmic Department of the Academic Medical Center in Amsterdam with pseudophakic endophthalmitis. Vitreous loss during cataract extraction was associated with a significantly increased risk of postoperative endophthalmitis when compared with uncomplicated cataract extraction (p 〈 0.0001). The incidence of pseudophakic endophthalmitis in diabetic patients was not significantly higher as compared to non-diabetic patients. Vitrectomy in the treatment of postoperative endophthalmitis did not improve the final visual acuity, probably because of selection bias. Methiciliin and cephazolin, used intravitreally against gram-positive organisms, failed to provide a good coverage for endophthalmitis due to Staphylococcus epidermidis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00157000
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  • 10
    Electronic Resource
    Electronic Resource
    Libri novi (1981)
    Springer
    Documenta ophthalmologica 52 (1981), S. 199-201 
    Details
    ISSN: 1573-2622
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01675206
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