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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 40 (1985), S. 0 
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Three cases of acute acalculous cholecystitis are reported in patients with multisystem failure following major long-bone trauma. The diagnosis should be suspected in any such patient who develops septicaemia from an unidentified site. A high index of suspicion should be maintained, especially in patients who are sedated or in receipt of mechanical ventilation of the lungs and in whom physical signs may be minimal or absent.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Intensive care medicine 23 (1997), S. 969-974 
    ISSN: 1432-1238
    Keywords: Key words Propofol ; Sedation ; Intensive care ; Tolerance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: To evaluate the possible development of tolerance in patients sedated with propofol in intensive care for more than 5 days. Design: An open within patient non-comparative pilot study. Setting: The intensive care unit of a hospital in the UK. Patients: Twenty-three patients who were expected to need sedation with propofol for more than 5 days were included; of these, 11 were sedated continuously for between 5 and 10 days. Interventions: Propofol was infused continuously at about 0.5–4 mg/kg per h to provide sedation at level 3 on the Ramsay scale (drowsy or asleep, responds easily to commands). Alfentanil was infused at a rate of about 0.5 μg/kg per min. Measurements and results: Patients with a statistically significant increase in both infusion rate and blood concentration were considered to show tolerance, those that required an increasing infusion rate and constant (or decreasing) blood concentration were said to show increased clearance, and those that required constant (or decreasing) infusion rates and blood concentrations were classed as showing no tolerance. Of the 11 patients who were sedated for more than 5 days, three showed tolerance and three showed increased clearance while five showed no tolerance. The desired sedation level was achieved for the majority of the time for patients sedated between 5 and 10 days (mean 73–90 %). There was some suggestion of a relationship between improving health (decreasing APACHE II scores) and the need for increased infusions of propofol. Conclusions: Although there were insufficient data to reach firm conclusions, the possibility of some relationship between the increasing need for propofol and improving condition in patients needing longer term intensive care cannot be ruled out.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-2242
    Keywords: Combining ability ; Host plant resistance Maize ; Fall armyworm ; Southwestern corn borer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The fall armyworm, Spodoptera frugiperda (J. E. Smith), and southwestern corn borer, Diatraea grandiosella Dyar, are major insect pests of maize, Zea mays L., in the southern USA. Both insects feed extensively on leaves of plants in the whorl stage of growth. A diallel cross of seven inbred lines with different levels of susceptibility to leaf feeding damage in the field was evaluated in a laboratory bioassay for fall armyworm and southwestern corn borer larval growth. Diets were prepared from lyophilized leaf tissue of field-grown plants of the inbred lines and their 21 F1 hybrids. One inbred line, Tx601, exhibited heavy leaf damage in field tests but showed moderate resistance in the laboratory bioassay. Both general and specific combining ability were highly significant sources of variation in the inheritance of fall armyworm and south-western corn borer larval growth in the laboratory bioassay. Tx601 showed excellent general combining ability for reduced larval growth of both species.
    Type of Medium: Electronic Resource
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