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  • 1
    Electronic Resource
    Electronic Resource
    The reliability of Tc-99m-DMSA scintigraphy in obstructive uropathy: is late scanning at 24 hours necessary? (1986)
    Springer
    World journal of urology 3 (1986), S. 253-255 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Differential kidney function is usually studied by quantification of relative renal uptake at 2–4 h after injection of the radiopharmaceutical99mTc-dimercaptosuccinic acid (DMSA). The outcome of this measurement, however, may be unreliable in cases of obstructive uropathy. The obstructed kidney may retain the radiopharmaceutical in the dilated system, which may lead to relatively high values for functioning cortical mass. In this situation, determination of the split kidney function at 24 h instead of 4 h after application of99mTc-DMSA has been advocated. In order to compare results at 4 h and 24 h an investigation was performed in 8 patients with obstructive renal disease present for more than 2 weeks, and in 7 patients who did not suffer from obstruction. In these 15 patients the differential function measured at 4 h and at 24 h was the same. From our results we conclude that overestimation of the function of an obstructed kidney by99mTc-DMSA scanning at 4 h is not a major problem. According to the literature, however, in cases of acute obstruction or “complicated” obstruction with stones or infection,99mTc-DMSA scintigraphy can underestimate the potential function of the obstructed kidney.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00632188
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  • 2
    Electronic Resource
    Electronic Resource
    Measurement of synovial inflammation in rheumatoid arthritis with technetium 99m labelled human polyclonal immunoglobulin G (1991)
    Springer
    European journal of nuclear medicine 18 (1991), S. 119-123 
    Details
    ISSN: 1619-7089
    Keywords: Technetium 99m human immunoglobulin ; Polyclonal human immunoglobulin (HIG) ; Rheumatoid arthritis scintigraphy ; Inflammation scintigraphy ; Scintigraphic quantitation of synovitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The ability of technetium 99m labelled nonspecific, polyclonal human immunoglobulin G (99mTc-IgG) scintigraphy to depict and quantify synovial inflammation was studied in patients with rheumatoid arthritis (RA). Eight patients with clinically active synovitis were injected with 350 MBq 99mTc-IgG, and imaging took place 4 h later. This resulted in excellent images of inflamed synovium. Significant correlations were observed between individual joint uptake on the scan and scores for joint pain (n=316, p〈0.001), joint swelling (n = 300, p 〈 0.001) or the average of pain and swelling (n = 300, p 〈 0.001). These results suggest that 99mTc-IgG scintigraphy may provide an objective, non-invasive test to detect and measure synovitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00175915
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Measurement of synovial inflammation in rheumatoid arthritis with technetium 99m labelled human polyclonal immunoglobulin G (1991)
    Springer
    European journal of nuclear medicine 18 (1991), S. 119-123 
    Details
    ISSN: 1619-7089
    Keywords: Technetium 99m human immunoglobulin ; Polyclonal human immunoglobulin (HIG) ; Rheumatoid arthritis scintigraphy ; Inflammation scintigraphy ; Scintigraphic quantitation of synovitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The ability of technetium 99m labelled nonspecific, polyclonal human immunoglobulin G (99mTc-IgG) scintigraphy to depict and quantify synovial inflammation was studied in patients with rheumatoid arthritis (RA). Eight patients with clinically active synovitis were injected with 350 MBq99mTc-IgG, and imaging took place 4 h later. This resulted in excellent images of inflamed synovium. Significant correlations were observed between individual joint uptake on the scan and scores for joint pain (n=316,p〈0.001), joint swelling (n = 300,p 〈 0.001) or the average of pain and swelling (n = 300,p 〈 0.001). These results suggest that99mTc-IgG scintigraphy may provide an objective, non-invasive test to detect and measure synovitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00950757
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    The acute effects of intravenous nisoldipine on left ventricular function 24 to 72 hours after uncomplicated acute myocardial infarction (1988)
    Springer
    Cardiovascular drugs and therapy 2 (1988), S. 673-678 
    Details
    ISSN: 1573-7241
    Keywords: nisoldipine ; acute myocardial infarction ; left ventricular function ; radionuclide angiography ; echocar-diography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The acute effects on left ventricular function of nisoldipine were studied in six patients 56±12 hours (range 44 to 72 hours) after the onset of uncomplicated acute myocardial infarction. Nisoldipine was administered as a 4.5 μg/kg intravenous bolus over 3 minutes followed by an infusion of 0.2 μg/kg during 60 minutes. Radionuclide angiography and two-dimensional echocardiography were performed before and during infusien with nisoldipine. The left ventricular ejection fraction increased significantly from 38%±10% to 49%±10% (P=0.028) during nisoldipine infusion. Regional wall motion index was determined both by radionuclide and by two-dimensional echocardiography and showed a significant change during nisoldipine infusion from 1.9±0.3 to 1.5±0.3 (p=0.028, radionuclide angiography) and from 0.7±0.2 to 0.3±0.2 (p=0.043, two dimensional echocardiography). Heart rate increased significantly from 78±12 min-1 to 92±13 min-1 (p=0.028), but mean double product did not change significantly during nisoldipine infusion. It is concluded that nisoldipine significantly improves global and regional left ventricular function in patients shortly after acute myocardial infarction. This beneficial effect may, however, be partially offset by an increase in heart rate. Since mean double product did not change, it is suggested that nisoldipine may improve coronary blood flow in patients with acute myocardial infarction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00054208
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    Paper (German National Licenses)
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