ISSN:
1546-1718
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Medicine
Notes:
[Auszug] The MDM2 protein negatively regulates -L the activity of the p53 tumour suppressor by binding its transcriptional activation domain1,2. In fact, the early embryonic lethality seen in mdm2 null embryos is due to an inability to inactivate p53, and is completely rescued by the absence of p53 (refs ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/ng0897-336
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