In:
United European Gastroenterology Journal, Wiley, Vol. 9, No. 5 ( 2021-06), p. 626-634
Abstract:
Summarise the established knowledge on this subject Mesenteric artery stenoses are prevalent (6%–29%), but as a result of the compensatory capacity of the mesenteric circulation, the incidence of chronic mesenteric ischaemia (CMI) is 9.2 per 100,000 Early risk stratification could facilitate the diagnostic trajectory of chronic mesenteric ischaemia in order to triage patients that do or do not need a further diagnostic workup The mesenteric artery calcium score (MACS) identifies CMI patients with a sensitivity of 88% and can be obtained from both non‐contrast enhanced and contrast enhanced computed tomography (CT) The score chart by van Dijk et al. might guide subsequent treatment decisions in patients with a clear suspicion of chronic mesenteric ischaemia, but requires an arterial contrast enhanced computed tomography angiography (CTA) What are the significant and/or new findings of this study? A CT‐based score chart composed of the variables weight loss, postprandial abdominal pain, cardiovascular disease, and MACS, showed excellent discrimination between patients with and without CMI The actual CMI risk was 2.1% in the predicted low‐risk group (0–4 points) of the MACS score chart and 39.1% in the increased risk group (5–10 points) of the MACS score chart The near‐perfect negative predictive value (97.9%) and sensitivity (97.8%) of the MACS score chart suggests that a score of ≤4 points virtually rules out CMI, while no patients are misclassified In this independent cohort the CTA‐based score chart by van Dijk et al. was confirmed to have an excellent discriminative ability to guide treatment decisions in patients with suspected CMI
Type of Medium:
Online Resource
ISSN:
2050-6406
,
2050-6414
Language:
English
Publisher:
Wiley
Publication Date:
2021
detail.hit.zdb_id:
2728585-6
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