In:
Eurosurveillance, European Centre for Disease Control and Prevention (ECDC), Vol. 25, No. 39 ( 2020-10-01)
Abstract:
We found that a single nucleotide polymorphism (SNP) in the nucleoprotein gene of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from a patient interfered with detection in a widely used commercial assay. Some 0.2% of the isolates in the EpiCoV database contain this SNP. Although SARS-CoV-2 was still detected by the other probe in the assay, this underlines the necessity of targeting two independent essential regions of a pathogen for reliable detection.
Type of Medium:
Online Resource
ISSN:
1560-7917
DOI:
10.2807/1560-7917.ES.2020.25.39.2001650
Language:
English
Publisher:
European Centre for Disease Control and Prevention (ECDC)
Publication Date:
2020
detail.hit.zdb_id:
2059112-3
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