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  • 1
    Online Resource
    Online Resource
    Predictive role of presenting symptoms and clinical findings in idiopathic intracranial hypertension
    Elsevier BV ; 2019
    In:  Journal of the Neurological Sciences Vol. 399 ( 2019-04), p. 89-93
    Details
    In: Journal of the Neurological Sciences, Elsevier BV, Vol. 399 ( 2019-04), p. 89-93
    Type of Medium: Online Resource
    ISSN: 0022-510X
    URL: Article
    DOI: 10.1016/j.jns.2019.02.006
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2019
    detail.hit.zdb_id: 1500645-1
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  • 2
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    Dialysis headache in patients undergoing peritoneal dialysis and hemodialysis
    Informa UK Limited ; 2015
    In:  Renal Failure Vol. 37, No. 2 ( 2015-02-07), p. 241-244
    Details
    In: Renal Failure, Informa UK Limited, Vol. 37, No. 2 ( 2015-02-07), p. 241-244
    Type of Medium: Online Resource
    ISSN: 0886-022X , 1525-6049
    URL: Article
    DOI: 10.3109/0886022X.2014.982486
    Language: English
    Publisher: Informa UK Limited
    Publication Date: 2015
    detail.hit.zdb_id: 2015459-8
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  • 3
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    Hemodialysis-related headaches
    National Library of Serbia ; 2007
    In:  Military Medical and Pharmaceutical Journal of Serbia Vol. 64, No. 5 ( 2007), p. 319-323
    Details
    In: Military Medical and Pharmaceutical Journal of Serbia, National Library of Serbia, Vol. 64, No. 5 ( 2007), p. 319-323
    Abstract: Uvod/Cilj. Hemodijaliza (HD) je terapijska procedura, koja se primenjuje sa ciljem delimicne korekcije homeostatskih poremecaja i prevencije pojave komplikacija uremije u terminalnoj fazi bubrezne insuficijencije. Cilj rada bio je da se utvrde i analiziraju ucestalost pojave i karakteristike glavobolja kod bolesnika koji su hronicno leceni hemodijalizama. Metode. Ispitivanjem su bila obuhvacena 143 bolesnika, 50 zena i 93 muskarca, na hronicnom lecenju HD. Anketiranje bolesnika obavljeno je uz koriscenje upitnika, uradjenog prema dijagnostickim kriterijumima Medjunarodne klasifikacije glavobolja (MKG) iz 2004. godine. Izdvojene su dve grupe bolesnika: oni koji nisu imali glavobolju i oni sa ponavljanim glavoboljama. Bolesnici sa ponavljanim glavoboljama podeljeni su na podgrupe: bolesnici kod kojih se glavobolja javljala i pre zapocinjanja lecenja HD i bolesnici kod kojih se glavobolja prvi put javila sa zapocinjanjem lecenja HD hemodijalizna glavobolja (HDG). U grupi bolesnika sa glavoboljama analizirane su karakteristike glavobolja prema kojima je postavljena dijagnoza glavobolja, kao i uticaj HD na glavobolju. Kod bolesnika sa HDG opisane su karakteristike ovih glavobolja. Bolesnici sa glavoboljama uporedjivani su sa grupom bolesnika bez glavobolja i to prema: polu i zivotnoj dobi, osnovnoj bolesti koja je dovela do terminalne faze bubrezne slabosti, prosecnom trajanju lecenja HD, vrednostima arterijskog krvnog pritiska u toku HD i serumskim vrednostima hemoglobina, ureje, kreatinina, natrijuma i kalijuma. Podaci su statisticki uporedjivani. Rezultati. Od 143 ispitana bolesnika, 27 (18,9%) je imalo ponavljane glavobolje. Nije nadjena statisticki znacajna razlika izmedju grupe bolesnika sa glavoboljama i grupe bolesnika bez glavobolja u odnosu na pol, zivotno doba, prosecno trajanje lecenja HD, osnovnu bolest, koja je i dovela do terminalnog stadijuma bubrezne insuficijencije, kao i srednje vrednosti serumske ureje, kreatinina, natrijuma i kalijuma. Uocena je statisticki znacajna razlika srednjih vrednosti sistolnog krvnog pritiska izmedju navedenih grupa bolesnika (p = 0,029). Statisticka znacajnost nije nadjena za srednje vrednosti dijastolnog krvnog pritiska. Kod 19 (13,3%) bolesnika glavobolja je postojala i pre zapocinjanja lecenja HD. Kod vise od polovine ovih bolesnika HD nije dovela do promena karakteristika glavobolje. Kod osam (5,6%) bolesnika dijagnostikovana je HDG prema dijagnostickim kriterijumima MKG iz 2004. godine. Ova glavobolja, prema rezultatima naseg ispitivanja pokazuje uniforman obrazac: javlja se vecinom kod muskaraca, skoro iskljucivo tokom cetvrtog sata dijalize, traje krace od cetiri sata, uglavnom je lokalizovana obostrano u prednjim partijama glave, jakog je intenziteta, pulsirajuceg kvaliteta i bez udruzenih simptoma. Zakljucak. Hemodijalizne glavobolje predstavljaju poseban entitet, ne samo zato sto su povezane sa HD, vec i stoga sto su kod svih ispitivanih bolesnika kod kojih su se pojavile pokazale veoma slicne karakteristike. Otkrivanje patofizioloskog mehanizma njihovog nastanka znacajno bi uticalo na kvalitet zivota bolesnika koji se lece primenom hemodijalize. .
    Type of Medium: Online Resource
    ISSN: 0042-8450 , 2406-0720
    URL: Article
    DOI: 10.2298/VSP0705319D
    Language: English
    Publisher: National Library of Serbia
    Publication Date: 2007
    detail.hit.zdb_id: 2169819-3
    SSG: 15,3
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  • 4
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    The burden and health care use of patients with migraine and tension-type headache in post-conflict area of Serbia
    SAGE Publications ; 2022
    In:  Cephalalgia Vol. 42, No. 9 ( 2022-08), p. 910-917
    Details
    In: Cephalalgia, SAGE Publications, Vol. 42, No. 9 ( 2022-08), p. 910-917
    Abstract: The aim of the present study was to assess the burden and health care use of adult patients with migraine and tension type headache in a post-conflict area of Serbia. Methods This cross-sectional study was conducted on a representative sample of adults, living in predominantly Serb communities on the Kosovo and Metohija territory. The required data was obtained through a survey, utilizing a culturally-adapted questionnaire. The study sample comprised of 1,062 adults. Results In the year preceding the study, 49.7% of included subjects suffering from migraines and 27.5% of those experiencing tension type headache sought medical assistance for their condition. The majority (88.5%) of the respondents utilized non steroid antiinfammatory drugs as analgesic, while 14.2% used prophylactic treatment. Migraine sufferers reported losing on average 11.1 days in a 3-month period, while those experiencing tension type headache lost 4.7 days (p  〈  0.001) due to headaches, preventing them from partaking in professional, family and social activities. On headache-free days, 24.5% of the respondents were anxious or tense in anticipation of a headache onset, while 30% did not feel that the headache had completely resolved. Moreover, 11.5% of the sample reported never or rarely feeling in control of the headache, while 20% of the respondents were of view that their headaches were not taken seriously by their employer and co-workers and rarely discuss them. Adverse effect of headaches on education is more frequently noted by migraine sufferers than those experiencing tension type headache (p = 0.001), and this disparity persists in relation to career (p  〈  0.001) and family planning (p = 0.001). Conclusions In Kosovo and Metohija, primary headaches exert a profound influence on the affected individuals and their community, and thus require recognition as one of the priorities of social initiatives aimed at the enhancement of public health.
    Type of Medium: Online Resource
    ISSN: 0333-1024 , 1468-2982
    URL: Article
    DOI: 10.1177/03331024221082061
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2019999-5
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  • 5
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    Cluster headache: pathophysiology, diagnosis and treatment
    Springer Science and Business Media LLC ; 2019
    In:  Journal of Neurology Vol. 266, No. 5 ( 2019-5), p. 1059-1066
    Details
    In: Journal of Neurology, Springer Science and Business Media LLC, Vol. 266, No. 5 ( 2019-5), p. 1059-1066
    Type of Medium: Online Resource
    ISSN: 0340-5354 , 1432-1459
    URL: Article
    DOI: 10.1007/s00415-018-9007-4
    RVK:
    XA 10000
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2019
    detail.hit.zdb_id: 1421299-7
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  • 6
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    Is the female sex associated with an increased risk for long-term cognitive decline after the first-ever lacunar stroke? Prospective study on small vessel disease cohort
    Frontiers Media SA ; 2023
    In:  Frontiers in Neurology Vol. 13 ( 2023-1-12)
    Details
    In: Frontiers in Neurology, Frontiers Media SA, Vol. 13 ( 2023-1-12)
    Abstract: Sex is a significant determinant of survival and functional outcome after stroke. Long-term cognitive outcome after acute lacunar stroke in the context of sex differences has been rarely reported. Methods A cohort of small vessel disease (SVD) patients presenting with first-ever acute lacunar stroke and normal cognitive status has been evaluated 4 years after the qualifying event for the presence of cognitive impairment (CI) with a comprehensive neuropsychological battery. Differences in baseline clinical and neuroimaging characteristics were compared between sexes in relation to cognitive status. Results A total of 124 female and 150 male patients were analyzed. No difference was detected between the groups regarding age ( p = 0.932) or frequency of common vascular risk factors ( p & gt; 0.1 for all). At the baseline assessment, women had more disabilities compared to men with a mean modified Rankin scale (mRS) score of 2.5 (1.5 in men, p & lt; 0.0001). Scores of white matter hyperintensities (WMH) of presumed vascular origin and a total number of lacunes of presumed vascular origin on brain MRI were higher in women compared to men ( p & lt; 0.0001 for all). As many as 64.6% of patients had CI of any severity on follow-up, women more frequently (77.4%) than men (54.0%; p & lt; 0.0001). Univariate logistic regression analysis showed that female sex, higher NIHSS and mRS scores, presence of depression, and increasing WMH severity were associated with an increased risk for CI. Multivariate regression analysis indicated that only depression (OR 1.74, 95%CI 1.25–2.44; p = 0.001) and WMH severity (OR 1.10, 95%CI 1.03–1.17; p = 0.004) were independently associated with the CI. Conclusion At the long-term follow-up, women lacunar stroke survivors, compared to men, more frequently had CI in the presence of more severe vascular brain lesions, but this association was dependent on the occurrence of depression and severity of WMH, and could not be explained by differences in common vascular risk factors.
    Type of Medium: Online Resource
    ISSN: 1664-2295
    URL: Article
    DOI: 10.3389/fneur.2022.1052401
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2023
    detail.hit.zdb_id: 2564214-5
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  • 7
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    Idiopathic Intracranial Hypertension – Pathophysiology Based on Case Series
    Walter de Gruyter GmbH ; 2016
    In:  Acta Facultatis Medicae Naissensis Vol. 33, No. 3 ( 2016-09-1), p. 199-209
    Details
    In: Acta Facultatis Medicae Naissensis, Walter de Gruyter GmbH, Vol. 33, No. 3 ( 2016-09-1), p. 199-209
    Abstract: According to the definition, idiopathic intracranial hypertension (IIH) is a pathological state characterized by an increase in intracranial pressure; however, there are no obvious intracranial pathological processes. The pathophysiology of this disorder is not clear, although there are many reports related to it. We present an overview of possible etiopathogenetic mechanisms, clinical presentations and therapeutic interventions from a series of patients hospitalized with the clinical picture and final diagnosis of idiopathic intracranial hypertension (IIH). All data were collected from the moment of IIH diagnosis as well as three months later. The obtained data showed that IIH is a disease that primarily affects obese women in early and midlife. The positive correlation between values of cerebrospinal fluid pressure and body mass index was observed. The disorders of sexual hormones were identified as a possible etiology for IIH female patients. Headache, papilloedema, decreased visual acuity, vertigo and cranial nerve palsy were identified as the most prevalent IIH clinical presentations. The existence of stenosis and hypoplasia of the sigmoid and transverse sinus were confirmed only in one third of IIH patients. Pharmacotherapy combined with weight loss was efficacious in a large number of patients. In this series, there were no short-term consequences of IIH. The results suggest the importance of early and accurate looking for IIH in obese early and midlife women with any hormonal imbalances having a variety of neurological expression, mostly presented as headaches and visual disturbances. Early detection of IIH might influence the timely treatment and prevent far-reaching and severe clinical consequences.
    Type of Medium: Online Resource
    ISSN: 2217-2521
    URL: Article
    DOI: 10.1515/afmnai-2016-0021
    Language: Unknown
    Publisher: Walter de Gruyter GmbH
    Publication Date: 2016
    detail.hit.zdb_id: 2577892-4
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  • 8
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    Dysphasia and Other Higher Cortical Dysfunctions During the Migraine Aura—a Systematic Review of Literature
    Springer Science and Business Media LLC ; 2020
    In:  Current Pain and Headache Reports Vol. 24, No. 2 ( 2020-02)
    Details
    In: Current Pain and Headache Reports, Springer Science and Business Media LLC, Vol. 24, No. 2 ( 2020-02)
    Type of Medium: Online Resource
    ISSN: 1531-3433 , 1534-3081
    URL: Article
    DOI: 10.1007/s11916-020-0836-3
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2020
    detail.hit.zdb_id: 2094180-8
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  • 9
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    Subcortical Volume Changes in Migraine with Aura
    XMLink ; 2019
    In:  Journal of Clinical Neurology Vol. 15, No. 4 ( 2019), p. 448-
    Details
    In: Journal of Clinical Neurology, XMLink, Vol. 15, No. 4 ( 2019), p. 448-
    Type of Medium: Online Resource
    ISSN: 1738-6586 , 2005-5013
    URL: Article
    DOI: 10.3988/jcn.2019.15.4.448
    Language: English
    Publisher: XMLink
    Publication Date: 2019
    detail.hit.zdb_id: 2500489-X
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  • 10
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    Plasminogen activator inhibitor-1 in the evolution of stroke
    National Library of Serbia ; 2004
    In:  Srpski arhiv za celokupno lekarstvo Vol. 132, No. 5-6 ( 2004), p. 143-147
    Details
    In: Srpski arhiv za celokupno lekarstvo, National Library of Serbia, Vol. 132, No. 5-6 ( 2004), p. 143-147
    Abstract: Ispitivana je fibrinoliticka aktivnosty akutnom periodu mozdanog udara posmatranjem nivoa inhibitora 1 aktivatora plazminogena (RAI), kao jednog od indikatora fibrinoliticke aktivnosti. S obzirom na ulogu PAI-1 u procesima aterogeneze i trombogeneze, odredjivan je nivo PAI-1 u plazmi kod 59 bolesnika (do 50 godina) sa aterotromboticnim mozdanim udarom (potvrdjen kompjuterizovanom tomografijom, odnosno magnetnom rezonancijom mozga) od 12.do24. casa (I analiza) i 30. dana od pocetka mozdanog udara (II analiza) i uporedjivan sa nivoom PAI-1 u plazmi ispitanika kontrolne grupe (57 zdravih ispitanika), koji je bio2,86?0,70 U/ml. Ustanovljeno je da je PAI-1 statisticki znacajno povisenu akutnom stanju mozdanog udara (I analiza:PAI-1=4,10?1,40 U/ml ,p〈0,001; II analiza:PAI-1=3,64?0,90U/ml,p〈0,001), odnosno snizena je fibrinoliticka aktivnost, posebno prvog dana od mozdanog udara, koja se u potpunosti ne popravlja ni posle 30 dana. Nije utvrdjena razlika u ponasanju PAI-1 izmedju podgrupa sa infarktom i lakunarnom ishemijom mozga (p〉0,05), kao ni izmedju bolesnika zenskog i muskog pola (p〉0,05). Uz znacajno povecanje vrednosti fibrinogena (4,65?1,00g/l; u kontrolnoj grupi 2,83?0,64 g/l, p〈0,001), ustanovljeno je i znacajno povecanje nivoa triglicerida (2,04?0,76 mmol/l; u kontrolnoj grupi 1,38+0,54 mmol/l, p〈0,001) i lipoproteina(a) (0,405?0,290 g/l; u kontrolnoj grupi 0,172?0,140 d/1, p〈0,001). Povecane vrednosti PAI-1, odnosno smanjena fibrinoliticka aktivnost ukazuju na mogucu ulogu snizene fibrinoliticke aktivnosti u patogenezi ishemijskog mozdanog udara, odnosno na rizik od ponovnog ishemijskog dogadjaja, koji je najveci neposredno po zavrsetku akutne faze i postepeno opada narednih nekoliko nedelja.
    Type of Medium: Online Resource
    ISSN: 0370-8179 , 2406-0895
    URL: Article
    DOI: 10.2298/SARH0406143J
    Language: English
    Publisher: National Library of Serbia
    Publication Date: 2004
    detail.hit.zdb_id: 2577665-4
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