In:
European Journal of Organic Chemistry, Wiley, Vol. 2010, No. 2 ( 2010-01), p. 326-332
Abstract:
Efficient methods have been developed for the direct synthesis of amides from aldehydes and a straightforward route to propiolamidines using cyclopentadienyl‐free rare‐earth metal amides [{(CH 2 SiMe 2 ){(2,6‐ i Pr 2 C 6 H 3 )N} 2 }Ln{N(SiMe 3 ) 2 }(THF)] [Ln = Yb ( 1 ), Y ( 2 ), Dy ( 3 ), Sm ( 4 ), Nd ( 5 )] as versatile catalysts. The results indicate that in the direct synthesis of amides from aldehydes the catalysts have the activity order 2 〉 1 3 4 5 . These methods have the advantage of easy preparation of the catalysts, low catalyst loading, high conversion of substrates to products, mild reaction conditions, and compatibility with a wide range of substrates.
Type of Medium:
Online Resource
ISSN:
1434-193X
,
1099-0690
DOI:
10.1002/ejoc.v2010:2
DOI:
10.1002/ejoc.200901015
Language:
English
Publisher:
Wiley
Publication Date:
2010
detail.hit.zdb_id:
1410000-9
detail.hit.zdb_id:
1475010-7
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