In:
Advanced Materials Research, Trans Tech Publications, Ltd., Vol. 581-582 ( 2012-10), p. 7-10
Abstract:
4-Aryl-hexahydroquinolines prepared by Hantzsch reaction from aromatic aldehydes obtained from lignin had been proved to be excellent antioxidant property. In view of polyhydroquinoline containing similarities in structure to the biologically important compound, 1,4-dihydropyridine, their antihypertensive activities were herein determined in spontaneously hypertensive rats (SHRs) during different time. The results show that those compounds possessing excellent antioxidant activity exhibit good antihypertensive property, and the compound containing syringyl moiety exhibit better antihypertensive activity than that containing guaiacyl moiety. This study suggests that those compounds may serve as promising agents for cure hypertension and free radical-related diseases.
Type of Medium:
Online Resource
ISSN:
1662-8985
DOI:
10.4028/www.scientific.net/AMR.581-582
DOI:
10.4028/www.scientific.net/AMR.581-582.7
Language:
Unknown
Publisher:
Trans Tech Publications, Ltd.
Publication Date:
2012
detail.hit.zdb_id:
2265002-7
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