In:
Frontiers in Public Health, Frontiers Media SA, Vol. 9 ( 2021-9-17)
Abstract:
Aim: We aimed to estimate the disease burden and risk factors attributable to ovarian cancer, and epidemiological trends at global, regional, and national levels. Methods: We described ovarian cancer data on incidence, mortality, and disability-adjusted life-years as well as age-standardized rates from 1990 to 2017 from the Global Health Data Exchange database. We also estimated the risk factors attributable to ovarian cancer deaths and disability-adjusted life-years. Measures were stratified by region, country, age, and socio-demographic index. The estimated annual percentage changes and age-standardized rates were calculated to evaluate temporal trends. Results: Globally, ovarian cancer incident, death cases, and disability-adjusted life-years increased by 88.01, 84.20, and 78.00%, respectively. However, all the corresponding age-standardized rates showed downward trends with an estimated annual percentage change of −0.10 (−0.03 to 0.16), −0.33 (−0.38 to −0.27), and −0.38 (−0.32 to 0.25), respectively. South and East Asia and Western Europe carried the heaviest disease burden. The highest incidence, deaths, and disability-adjusted life-years were mainly in people aged 50–69 years from 1990 to 2017. High fasting plasma glucose level was the greatest contributor in age-standardized disability-adjusted life-years rate globally as well as in all socio-demographic index quintiles and most Global Disease Burden regions. Other important factors were high body mass index and occupational exposure to asbestos. Conclusion: Our study provides valuable information on patterns and trends of disease burden and risk factors attributable to ovarian cancer across age, socio-demographic index, region, and country, which may help improve the rational allocation of health resources as well as inform health policies.
Type of Medium:
Online Resource
ISSN:
2296-2565
DOI:
10.3389/fpubh.2021.619581
DOI:
10.3389/fpubh.2021.619581.s001
DOI:
10.3389/fpubh.2021.619581.s002
DOI:
10.3389/fpubh.2021.619581.s003
DOI:
10.3389/fpubh.2021.619581.s004
DOI:
10.3389/fpubh.2021.619581.s005
DOI:
10.3389/fpubh.2021.619581.s006
DOI:
10.3389/fpubh.2021.619581.s007
DOI:
10.3389/fpubh.2021.619581.s008
DOI:
10.3389/fpubh.2021.619581.s009
DOI:
10.3389/fpubh.2021.619581.s010
DOI:
10.3389/fpubh.2021.619581.s011
DOI:
10.3389/fpubh.2021.619581.s012
DOI:
10.3389/fpubh.2021.619581.s013
DOI:
10.3389/fpubh.2021.619581.s014
DOI:
10.3389/fpubh.2021.619581.s015
DOI:
10.3389/fpubh.2021.619581.s016
Language:
Unknown
Publisher:
Frontiers Media SA
Publication Date:
2021
detail.hit.zdb_id:
2711781-9
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