GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
Material
Publisher
Person/Organisation
Language
Years
FID
Subjects(RVK)
  • 1
    Online Resource
    Online Resource
    Added-value of texture analysis of ADC in predicting the survival of patients with 2018 FIGO stage IIICr cervical cancer treated by concurrent chemoradiotherapy
    Elsevier BV ; 2022
    In:  European Journal of Radiology Vol. 150 ( 2022-05), p. 110272-
    Details
    In: European Journal of Radiology, Elsevier BV, Vol. 150 ( 2022-05), p. 110272-
    Type of Medium: Online Resource
    ISSN: 0720-048X
    URL: Article
    DOI: 10.1016/j.ejrad.2022.110272
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2022
    detail.hit.zdb_id: 138815-0
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Natural variations in the P-type ATPase heavy metal transporter gene ZmHMA3 control cadmium accumulation in maize grains
    Oxford University Press (OUP) ; 2021
    In:  Journal of Experimental Botany Vol. 72, No. 18 ( 2021-09-30), p. 6230-6246
    Details
    In: Journal of Experimental Botany, Oxford University Press (OUP), Vol. 72, No. 18 ( 2021-09-30), p. 6230-6246
    Abstract: Cadmium (Cd) accumulation in maize grains is detrimental to human health. Developing maize varieties with low Cd content is important for safe consumption of maize grains. However, the key genes controlling maize grain Cd accumulation have not been cloned. Here, we identified one major locus for maize grain Cd accumulation (qCd1) using a genome-wide association study (GWAS) and bulked segregant RNA-seq analysis with a biparental segregating population of Jing724 (low-Cd line) and Mo17 (high-Cd line). The candidate gene ZmHMA3 was identified by fine mapping and encodes a tonoplast-localized heavy metal P-type ATPase transporter. An ethyl methane sulfonate mutant analysis and an allelism test confirmed that ZmHMA3 influences maize grain Cd accumulation. A transposon in intron 1 of ZmHMA3 is responsible for the abnormal amino acid sequence in Mo17. Based on the natural sequence variations in the ZmHMA3 gene of diverse maize lines, four PCR-based molecular markers were developed, and these were successfully used to distinguish five haplotypes with different grain Cd contents in the GWAS panel and to predict grain Cd contents of widely used maize inbred lines and hybrids. These molecular markers can be used to breed elite maize varieties with low grain Cd contents.
    Type of Medium: Online Resource
    ISSN: 0022-0957 , 1460-2431
    URL: Article
    DOI: 10.1093/jxb/erab254
    RVK:
    WA 15000
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2021
    detail.hit.zdb_id: 2976-2
    detail.hit.zdb_id: 1466717-4
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    MRI-based radiomics value for predicting the survival of patients with locally advanced cervical squamous cell cancer treated with concurrent chemoradiotherapy
    Springer Science and Business Media LLC ; 2022
    In:  Cancer Imaging Vol. 22, No. 1 ( 2022-12)
    Details
    In: Cancer Imaging, Springer Science and Business Media LLC, Vol. 22, No. 1 ( 2022-12)
    Abstract: To investigate the magnetic resonance imaging (MRI)-based radiomics value in predicting the survival of patients with locally advanced cervical squamous cell cancer (LACSC) treated with concurrent chemoradiotherapy (CCRT). Methods A total of 185 patients (training group: n  = 128; testing group: n  = 57) with LACSC treated with CCRT between January 2014 and December 2018 were retrospectively enrolled in this study. A total of 400 radiomics features were extracted from T2-weighted imaging, apparent diffusion coefficient map, arterial- and delayed-phase contrast-enhanced MRI. Univariate Cox regression and least absolute shrinkage and selection operator Cox regression was applied to select radiomics features and clinical characteristics that could independently predict progression-free survival (PFS) and overall survival (OS). The predictive capability of the prediction model was evaluated using Harrell’s C-index. Nomograms and calibration curves were then generated. Survival curves were generated using the Kaplan-Meier method, and the log-rank test was used for comparison. Results The radiomics score achieved significantly better predictive performance for the estimation of PFS (C-index, 0.764 for training and 0.762 for testing) and OS (C-index, 0.793 for training and 0.750 for testing), compared with the 2018 FIGO staging system (C-index for PFS, 0.657 for training and 0.677 for testing; C-index for OS, 0.665 for training and 0.633 for testing) and clinical-predicting model (C-index for PFS, 0.731 for training and 0.725 for testing; C-index for OS, 0.708 for training and 0.693 for testing) ( P   〈  0.05). The combined model constructed with T stage, lymph node metastasis position, and radiomics score achieved the best performance for the estimation of PFS (C-index, 0.792 for training and 0.809 for testing) and OS (C-index, 0.822 for training and 0.785 for testing), which were significantly higher than those of the radiomics score ( P   〈  0.05). Conclusions The MRI-based radiomics score could provide effective information in predicting the PFS and OS in patients with LACSC treated with CCRT. The combined model (including MRI-based radiomics score and clinical characteristics) showed the best prediction performance.
    Type of Medium: Online Resource
    ISSN: 1470-7330
    URL: Article
    DOI: 10.1186/s40644-022-00474-2
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2104862-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Exploring the relevance between load-bearing capacity and surface friction behavior based on a layered hydrogel cartilage prototype
    Springer Science and Business Media LLC ; 2024
    In:  Friction Vol. 12, No. 8 ( 2024-08), p. 1757-1770
    Details
    In: Friction, Springer Science and Business Media LLC, Vol. 12, No. 8 ( 2024-08), p. 1757-1770
    Abstract: Cartilage is well lubricated over a lifetime and this phenomenon is attributed to both of the surface hydration lubrication and the matrix load-bearing capacity. Lubricious hydrogels with a layered structure are designed to mimic cartilage as potential replacements. While many studies have concentrated on improving surface hydration to reduce friction, few have experimentally detected the relationship between load-bearing capacity of hydrogels and their interface friction behavior. In this work, a bilayer hydrogel, serving as a cartilage prototype consisted of a top thick hydrated polymer brush layer and a bottom hydrogel matrix with tunable modulus was designed to investigate this relationship. The coefficient of friction (COF, μ ) is defined as the sum of interfacial component ( μ Int ) and deformation/hysteresis component ( μ Hyst ). The presence of the top hydration layer effectively dissipates contact stress and reduces the interface interaction ( μ Int ), leading to a stable and low COF. The contribution of mechanical deformation ( μ Hyst ) during the sliding shearing process to COF can be significantly reduced by increasing the local mechanical modulus, thereby enhancing the load-bearing capacity. These results show that the strategy of coupling surface hydration layer with a high load-bearing matrix can indeed enhance the lubrication performance of hydrogel cartilage prototypes, and implies a promising routine for designing robust soft matter lubrication system and friction-control devices.
    Type of Medium: Online Resource
    ISSN: 2223-7690 , 2223-7704
    URL: Article
    DOI: 10.1007/s40544-023-0846-3
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2024
    detail.hit.zdb_id: 2787589-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    Gene-Indexed Mutations in Maize
    Elsevier BV ; 2018
    In:  Molecular Plant Vol. 11, No. 3 ( 2018-03), p. 496-504
    Details
    In: Molecular Plant, Elsevier BV, Vol. 11, No. 3 ( 2018-03), p. 496-504
    Type of Medium: Online Resource
    ISSN: 1674-2052
    URL: Article
    DOI: 10.1016/j.molp.2017.11.013
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2018
    detail.hit.zdb_id: 2457758-3
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    Successive Redox‐Reaction‐Triggered Interface Radical Polymerization for Growing Hydrogel Coatings on Diverse Substrates
    Wiley ; 2022
    In:  Angewandte Chemie Vol. 134, No. 39 ( 2022-09-26)
    Details
    In: Angewandte Chemie, Wiley, Vol. 134, No. 39 ( 2022-09-26)
    Abstract: Growing lubricating hydrogel coatings in controllable manners on diverse material surfaces demonstrates promising applications. Here, a surface modification method is reported for in situ growing hydrogel coatings onto surfaces of diverse substrates in the absence of UV assistance. It is performed by decorating substrates with a universal mussel‐inspired synthetic adhesive with catechol groups. Upon being immersed in reaction solution, these groups can assist substrate bonding and in situ capture and reduce Fe 3+ into Fe 2+ for decomposing S 2 O 8 2− into SO 4 − ⋅ catalytically at the interface to initiate interface polymerization of monomers. As a result, hydrogel coatings with controllable thickness could be grown on surfaces of arbitrary substrates to change their surface characteristics regardless of materials size, category, geometry and transparency, implying considerable potential in surface engineering.
    Type of Medium: Online Resource
    ISSN: 0044-8249 , 1521-3757
    URL: Issue
    URL: Article
    DOI: 10.1002/ange.v134.39
    DOI: 10.1002/ange.202209741
    RVK:
    VA 2100
    RVK:
    VN 5020
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 506609-8
    detail.hit.zdb_id: 1479266-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 7
    Online Resource
    Online Resource
    Genome-wide selection signatures detection in Shanghai Holstein cattle population identified genes related to adaption, health and reproduction traits
    Springer Science and Business Media LLC ; 2021
    In:  BMC Genomics Vol. 22, No. 1 ( 2021-10-15)
    Details
    In: BMC Genomics, Springer Science and Business Media LLC, Vol. 22, No. 1 ( 2021-10-15)
    Abstract: Over several decades, a wide range of natural and artificial selection events in response to subtropical environments, intensive pasture and intensive feedlot systems have greatly changed the customary behaviour, appearance, and important economic traits of Shanghai Holstein cattle. In particular, the longevity of the Shanghai Holstein cattle population is generally short, approximately the 2nd to 3rd lactation. In this study, two complementary approaches, integrated haplotype score (iHS) and runs of homozygosity (ROH), were applied for the detection of selection signatures within the genome using genotyping by genome-reduced sequence data from 1092 cows. Results In total, 101 significant iHS genomic regions containing selection signatures encompassing a total of 256 candidate genes were detected. There were 27 significant |iHS| genomic regions with a mean |iHS| score  〉  2. The average number of ROH per individual was 42.15 ± 25.47, with an average size of 2.95 Mb. The length of 78 % of the detected ROH was within the range of 1–2 MB and 2–4 MB, and 99 % were shorter than 8 Mb. A total of 168 genes were detected in 18 ROH islands (top 1 %) across 16 autosomes, in which each SNP showed a percentage of occurrence  〉  30 %. There were 160 and 167 genes associated with the 52 candidate regions within health-related QTL intervals and 59 candidate regions within reproduction-related QTL intervals, respectively. Annotation of the regions harbouring clustered |iHS| signals and candidate regions for ROH revealed a panel of interesting candidate genes associated with adaptation and economic traits, such as IL22RA1, CALHM3, ITGA9, NDUFB3, RGS3, SOD2, SNRPA1, ST3GAL4, ALAD, EXOSC10 , and MASP2 . In a further step, a total of 1472 SNPs in 256 genes were matched with 352 cis -eQTLs in 21 tissues and 27 trans -eQTLs in 6 tissues. For SNPs located in candidate regions for ROH, a total of 108 cis -eQTLs in 13 tissues and 4 trans -eQTLs were found for 1092 SNPs. Eighty-one eGenes were significantly expressed in at least one tissue relevant to a trait ( P value  〈  0.05) and matched the 256 genes detected by iHS. For the 168 significant genes detected by ROH, 47 gene-tissue pairs were significantly associated with at least one of the 37 traits. Conclusions We provide a comprehensive overview of selection signatures in Shanghai Holstein cattle genomes by combining iHS and ROH. Our study provides a list of genes associated with immunity, reproduction and adaptation. For functional annotation, the cGTEx resource was used to interpret SNP-trait associations. The results may facilitate the identification of genes relevant to important economic traits and can help us better understand the biological processes and mechanisms affected by strong ongoing natural or artificial selection in livestock populations.
    Type of Medium: Online Resource
    ISSN: 1471-2164
    URL: Article
    DOI: 10.1186/s12864-021-08042-x
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2041499-7
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 8
    Online Resource
    Online Resource
    In vitro adsorption mechanism of acrylamide by lactic acid bacteria
    Elsevier BV ; 2019
    In:  LWT Vol. 100 ( 2019-02), p. 119-125
    Details
    In: LWT, Elsevier BV, Vol. 100 ( 2019-02), p. 119-125
    Type of Medium: Online Resource
    ISSN: 0023-6438
    URL: Article
    DOI: 10.1016/j.lwt.2018.10.058
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2019
    detail.hit.zdb_id: 1140230-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 9
    Online Resource
    Online Resource
    DataSheet1.docx
    Frontiers Media SA ; 2022
    In:  Frontiers in Genetics Vol. 13 ( 2022-9-5)
    Details
    In: Frontiers in Genetics, Frontiers Media SA, Vol. 13 ( 2022-9-5)
    Abstract: The aim of this study was to investigate the genetic parameters and genetic architectures of six milk production traits in the Shanghai Holstein population. The data used to estimate the genetic parameters consisted of 1,968,589 test-day records for 305,031 primiparous cows. Among the cows with phenotypes, 3,016 cows were genotyped with Illumina Bovine SNP50K BeadChip, GeneSeek Bovine 50K BeadChip, GeneSeek Bovine LD BeadChip v4, GeneSeek Bovine 150K BeadChip, or low-depth whole-genome sequencing. A genome-wide association study was performed to identify quantitative trait loci and genes associated with milk production traits in the Shanghai Holstein population using genotypes imputed to whole-genome sequences and both fixed and random model circulating probability unification and a mixed linear model with rMVP software. Estimated heritabilities (h2) varied from 0.04 to 0.14 for somatic cell score (SCS), 0.07 to 0.22 for fat percentage (FP), 0.09 to 0.27 for milk yield (MY), 0.06 to 0.23 for fat yield (FY), 0.09 to 0.26 for protein yield (PY), and 0.07 to 0.35 for protein percentage (PP), respectively. Within lactation, genetic correlations for SCS, FP, MY, FY, PY, and PP at different stages of lactation estimated in random regression model were ranged from -0.02 to 0.99, 0.18 to 0.99, 0.04 to 0.99, 0.04 to 0.99, 0.01 to 0.99, and 0.33 to 0.99, respectively. The genetic correlations were highest between adjacent DIM but decreased as DIM got further apart. Candidate genes included those related to production traits ( DGAT1 , MGST1 , PTK2 , and SCRIB ), disease-related ( LY6K , COL22A1 , TECPR2 , and PLCB1 ), heat stress–related ( ITGA9 , NDST4 , TECPR2 , and HSF1 ), and reproduction-related ( 7SK and DOCK2 ) genes. This study has shown that there are differences in the genetic mechanisms of milk production traits at different stages of lactation. Therefore, it is necessary to conduct research on milk production traits at different stages of lactation as different traits. Our results can also provide a theoretical basis for subsequent molecular breeding, especially for the novel genetic loci.
    Type of Medium: Online Resource
    ISSN: 1664-8021
    URL: Article
    URL: Article
    DOI: 10.3389/fgene.2022.940650
    DOI: 10.3389/fgene.2022.940650.s001
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2606823-0
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 10
    Online Resource
    Online Resource
    Robust Super‐Lubricity for Novel Cartilage Prototype Inspired by Scallion Leaf Architecture
    Wiley ; 2024
    In:  Advanced Functional Materials Vol. 34, No. 16 ( 2024-04)
    Details
    In: Advanced Functional Materials, Wiley, Vol. 34, No. 16 ( 2024-04)
    Abstract: The simultaneous achievement ‐under physiologically high contact pressures‐ of ultra‐low friction, nearly zero surface wear, and long lifetime in the development of human cartilage prosthetics is still a big challenge. In this work, inspired by the unique lubrication mechanism of scallion leaves resulting from the synergy of oriented surface micro‐topography and mucus hydration, a novel layered soft hydrogel as cartilage prototype is developed by chemically embedding thick hydrophilic polyelectrolyte brush chains into the sub‐surface of a high strength anisotropic hydrogel bulk. It exhibits an anisotropic polymer network with unique mechanical properties (tensile strength: 8.3 to 23.7 MPa; elastic modulus 20.0 to 30.0 MPa), anisotropic hydrated surface texture, super‐lubricity, and excellent wear resistance. Thydrogel architecture can exhibit low coefficient of friction (COF) less than ≈0.01 under a wide range of contact stresses (0.2 to 2.4 MPa) and maintain cartilage‐like long‐lasting (50k sliding cycles) robust super‐lubricity (COF ≈ 0.006) and nearly‐zero wear under high contact pressure (≈2.4 MPa) condition. Theoretical underpinning reveals how multiscale surface anisotropy, mechanics, and hydration regulate super‐low friction generation. This work provides a novel design paradigm for the fabrication of robust soft materials with extraordinary lubricity as implantable prototypes and coatings.
    Type of Medium: Online Resource
    ISSN: 1616-301X , 1616-3028
    URL: Issue
    URL: Article
    DOI: 10.1002/adfm.v34.16
    DOI: 10.1002/adfm.202310271
    Language: English
    Publisher: Wiley
    Publication Date: 2024
    detail.hit.zdb_id: 2029061-5
    detail.hit.zdb_id: 2039420-2
    SSG: 11
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...